| O1;O2;1 | 
                RUSPBB207;71.48;1 | 
                RN0001 | 
                rmlA | 
                glucose-1-phosphate thymidylyltransferase | 
                RmlA | 
                Glc-1-P | 
                dTDP-D-Glc | 
                dTDP-L-Rha | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-L-Rha | 
                SynPath0001 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;2 | 
                RUSPBB207;71.48;2 | 
                RN0002 | 
                rmlB | 
                dTDP-d-glucose-4,6-dehydratase | 
                RmlB | 
                dTDP-D-Glc | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-L-Rha | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-L-Rha | 
                SynPath0001 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;3 | 
                RUSPBB207;71.48;3 | 
                RN0003 | 
                rmlC | 
                dTDP-4-keto-6-deoxy-d-glucose 3,5-epimerase | 
                RmlC | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-6-deoxy-L-lyxo-hexos-4-ulose | 
                dTDP-L-Rha | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-L-Rha | 
                SynPath0001 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;4 | 
                RUSPBB207;71.48;4 | 
                RN0004 | 
                rmlD | 
                dTDP-6-deoxy-l-mannose-dehydrogenase  | 
                RmlD | 
                dTDP-6-deoxy-L-lyxo-hexos-4-ulose | 
                dTDP-L-Rha | 
                dTDP-L-Rha | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-L-Rha | 
                SynPath0001 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;5 | 
                RUSPBB207;71.48;5 | 
                RN0001 | 
                rmlA | 
                glucose-1-phosphate thymidylyltransferase | 
                RmlA | 
                Glc-1-P | 
                dTDP-D-Glc | 
                dTDP-6d-L-Rha | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-6d-L-Rha | 
                SynPath0002 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;6 | 
                RUSPBB207;71.48;6 | 
                RN0002 | 
                rmlB | 
                dTDP-d-glucose-4,6-dehydratase | 
                RmlB | 
                dTDP-D-Glc | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-6d-L-Rha | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-6d-L-Rha | 
                SynPath0002 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;7 | 
                RUSPBB207;71.48;7 | 
                RN0003 | 
                rmlC | 
                dTDP-4-keto-6-deoxy-d-glucose 3,5-epimerase | 
                RmlC | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-6-deoxy-L-lyxo-hexos-4-ulose | 
                dTDP-6d-L-Rha | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-6d-L-Rha | 
                SynPath0002 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;8 | 
                none;8 | 
                RN0005 | 
                t11 | 
                none | 
                T11 | 
                dTDP-6-deoxy-L-lyxo-hexos-4-ulose | 
                dTDP-6d-L-Rha | 
                dTDP-6d-L-Rha | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-6d-L-Rha | 
                SynPath0002 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;9 | 
                RUSPBB207;71.48;9 | 
                RN0001 | 
                rmlA | 
                glucose-1-phosphate thymidylyltransferase | 
                RmlA | 
                Glc-1-P | 
                dTDP-D-Glc | 
                dTDP-D-Fuc3NAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc3NAc | 
                SynPath0003 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;10 | 
                RUSPBB207;71.48;10 | 
                RN0002 | 
                rmlB | 
                dTDP-d-glucose-4,6-dehydratase | 
                RmlB | 
                dTDP-D-Glc | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-D-Fuc3NAc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc3NAc | 
                SynPath0003 | 
                
                    
                     
                    
                 | 
            
            
            
                | O2;O5;11 | 
                655;WP5-S18-ESBL-07;11 | 
                RN0006 | 
                fdtA | 
                dTDP-6-deoxy-hex-4-ulose isomerase | 
                FdtA | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-6-deoxy-D-xylohex-3-ulose | 
                dTDP-D-Fuc3NAc | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc3NAc | 
                SynPath0003 | 
                
                    
                     
                    
                 | 
            
            
            
                | O2;O50;12 | 
                655;WP5-S18-ESBL-07;12 | 
                RN0007 | 
                fdtB | 
                dTDP-6-deoxy-d-xylo-hex-3-ulose aminase | 
                FdtB | 
                dTDP-6-deoxy-D-xylohex-4-ulose | 
                dTDP-D-Fuc3N | 
                dTDP-D-Fuc3NAc | 
                step4 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc3NAc | 
                SynPath0003 | 
                
                    
                     
                    
                 | 
            
            
            
                | O2;O50;13 | 
                655;WP5-S18-ESBL-07;13 | 
                RN0008 | 
                fdtC | 
                dTDP-d-Fuc3N acetylase | 
                FdtC | 
                dTDP-6-deoxy-D-xylohex-3-ulose | 
                dTDP-D-Fuc3NAc | 
                dTDP-D-Fuc3NAc | 
                step5-End | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc3NAc | 
                SynPath0003 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;14 | 
                RUSPBB207;71.48;14 | 
                RN0001 | 
                rmlA | 
                glucose-1-phosphate thymidylyltransferase | 
                RmlA | 
                Glc-1-P | 
                dTDP-D-Glc | 
                dTDP-D-Qui3NAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui3NAc | 
                SynPath0004 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;15 | 
                RUSPBB207;71.48;15 | 
                RN0002 | 
                rmlB | 
                dTDP-d-glucose-4,6-dehydratase | 
                RmlB | 
                dTDP-D-Glc | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-D-Qui3NAc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui3NAc | 
                SynPath0004 | 
                
                    
                     
                    
                 | 
            
            
            
                | O65;O71;16 | 
                E8V1A;B024ch;16 | 
                RN0009 | 
                qdtA | 
                dTDP-4-oxo-6-deoxy-d-glucose3,4-oxoisomerase | 
                QdtA | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-3-oxo-6-deoxy-d-glucose | 
                dTDP-D-Qui3NAc | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui3NAc | 
                SynPath0004 | 
                
                    
                     
                    
                 | 
            
            
            
                | O5;O65;17 | 
                ECO5_196;HT2012ST03;17 | 
                RN0010 | 
                qdtB | 
                dTDP-3-oxo-6-deoxy-d-glucose aminase | 
                QdtB | 
                dTDP-3-oxo-6-deoxy-d-glucose | 
                dTDP-D-Quip3N | 
                dTDP-D-Qui3NAc | 
                step4 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui3NAc | 
                SynPath0004 | 
                
                    
                     
                    
                 | 
            
            
            
                | O5;O65;18 | 
                ECO5_196;HT2012ST03;18 | 
                RN0011 | 
                qdtC | 
                dTDP-d-Qui3N acetylase | 
                QdtC | 
                dTDP-D-Quip3N | 
                dTDP-D-Qui3NAc | 
                dTDP-D-Qui3NAc | 
                step5-End | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui3NAc | 
                SynPath0004 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;19 | 
                RUSPBB207;71.48;19 | 
                RN0001 | 
                rmlA | 
                glucose-1-phosphate thymidylyltransferase | 
                RmlA | 
                Glc-1-P | 
                dTDP-D-Glc | 
                dTDP-D-Fuc4NAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc4NAc | 
                SynPath0005 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;20 | 
                RUSPBB207;71.48;20 | 
                RN0002 | 
                rmlB | 
                dTDP-d-glucose-4,6-dehydratase | 
                RmlB | 
                dTDP-D-Glc | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                dTDP-D-Fuc4NAc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc4NAc | 
                SynPath0005 | 
                
                    
                     
                    
                 | 
            
            
            
                | O10;21 | 
                SAX-C46;NS-NP007;21 | 
                RN0012 | 
                fdfA | 
                aminotransferase | 
                FdfA | 
                dTDP-6-deoxy-D-xylo-hexos-4-ulose | 
                undefined | 
                dTDP-D-Fuc4NAc | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc4NAc | 
                SynPath0005 | 
                
                    
                     
                    
                 | 
            
            
            
                | O10;22 | 
                SAX-C46;NS-NP007;22 | 
                RN0013 | 
                fdfB | 
                acetyltransferase | 
                FdfB | 
                undefined | 
                dTDP-D-Fuc4NAc | 
                dTDP-D-Fuc4NAc | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fuc4NAc | 
                SynPath0005 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;23 | 
                RUSPBB207;71.48;23 | 
                RN0001 | 
                rmlA | 
                glucose-1-phosphate thymidylyltransferase | 
                RmlA | 
                Glc-1-P | 
                dTDP-D-Glc | 
                dTDP-D-Qui4NAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui4NAc | 
                SynPath0006 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;24 | 
                RUSPBB207;71.48;24 | 
                RN0002 | 
                rmlB | 
                dTDP-d-glucose-4,6-dehydratase | 
                RmlB | 
                dTDP-D-Glc | 
                dTDP-D-Glc4O | 
                dTDP-D-Qui4NAc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui4NAc | 
                SynPath0006 | 
                
                    
                     
                    
                 | 
            
            
            
                | O7;O39;25 | 
                IBS44;upec-221;25 | 
                RN0014 | 
                vioA | 
                aminotransferase | 
                VioA | 
                dTDP-D-Glc4O | 
                dTDP-D-Qui4N | 
                dTDP-D-Qui4NAc | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui4NAc | 
                SynPath0006 | 
                
                    
                     
                    
                 | 
            
            
            
                | O7;O39;26 | 
                IBS44;upec-221;26 | 
                RN0015 | 
                vioB | 
                N-acetyltransferase | 
                VioB | 
                dTDP-D-Qui4N | 
                dTDP-D-Qui4NAc | 
                dTDP-D-Qui4NAc | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Qui4NAc | 
                SynPath0006 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;27 | 
                RUSPBB207;71.48;27 | 
                RN0001 | 
                rmlA | 
                glucose-1-phosphate thymidylyltransferase | 
                RmlA | 
                Glc-1-P | 
                dTDP-D-Glc | 
                dTDP-D-Fucf | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fucf | 
                SynPath0007 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O2;28 | 
                RUSPBB207;71.48;28 | 
                RN0002 | 
                rmlB | 
                dTDP-d-glucose-4,6-dehydratase | 
                RmlB | 
                dTDP-D-Glc | 
                dTDP-D-Glc4O | 
                dTDP-D-Fucf | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fucf | 
                SynPath0007 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;29 | 
                none;29 | 
                RN0016 | 
                fcfA | 
                C-4 reductase | 
                FcfA | 
                dTDP-D-Glc4O | 
                dTDP-D-Fuc | 
                dTDP-D-Fucf | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fucf | 
                SynPath0007 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;30 | 
                none;30 | 
                RN0017 | 
                fcfB | 
                mutase | 
                FcfB | 
                dTDP-D-Fuc | 
                dTDP-D-Fucf | 
                dTDP-D-Fucf | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-dTDP-D-Fucf | 
                SynPath0007 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;31 | 
                none;31 | 
                RN0018 | 
                manA | 
                phosphomannose isomerase | 
                ManA | 
                Fru-6-P | 
                D-Man-6-P | 
                GDP-L-Fuc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Fuc | 
                SynPath0008 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O7;32 | 
                RHB39-C23;NCTC11105;32 | 
                RN0019 | 
                manB | 
                phosphomannomutase | 
                ManB | 
                D-Man-6-P | 
                D-Man-1-P | 
                GDP-L-Fuc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Fuc | 
                SynPath0008 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O7;33 | 
                RHB39-C23;NCTC11105;33 | 
                RN0020 | 
                manC | 
                mannose-1-phosphate guanylyltransferase | 
                ManC | 
                D-Man-1-P | 
                GDP-D-Man | 
                GDP-L-Fuc | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Fuc | 
                SynPath0008 | 
                
                    
                     
                    
                 | 
            
            
            
                | O11;O36;34 | 
                HVH 121 (4-6877826);S56CTX;34 | 
                RN0021 | 
                gmd | 
                 GDP-mannose-4,6-dehydratase | 
                Gmd | 
                GDP-Man | 
                GDP-4-keto-6-D-deoxymannose | 
                GDP-L-Fuc | 
                step4 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Fuc | 
                SynPath0008 | 
                
                    
                     
                    
                 | 
            
            
            
                | O11;O36;35 | 
                HVH 121 (4-6877826);S56CTX;35 | 
                RN0022 | 
                fcl | 
                GDP-l-fucose synthetase | 
                Fcl | 
                GDP-4-keto-6-D-deoxymannose | 
                GDP-L-Fuc | 
                GDP-L-Fuc | 
                step5-End | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Fuc | 
                SynPath0008 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;36 | 
                none;36 | 
                RN0018 | 
                manA | 
                phosphomannose isomerase | 
                ManA | 
                Fru-6-P | 
                D-Man-6-P | 
                GDP-L-Col | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Col | 
                SynPath0009 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O7;37 | 
                RHB39-C23;NCTC11105;37 | 
                RN0019 | 
                manB | 
                phosphomannomutase | 
                ManB | 
                D-Man-6-P | 
                D-Man-1-P | 
                GDP-L-Col | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Col | 
                SynPath0009 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O7;38 | 
                RHB39-C23;NCTC11105;38 | 
                RN0020 | 
                manC | 
                mannose-1-phosphate guanylyltransferase | 
                ManC | 
                D-Man-1-P | 
                GDP-D-Man | 
                GDP-L-Col | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Col | 
                SynPath0009 | 
                
                    
                     
                    
                 | 
            
            
            
                | O11;O36;39 | 
                HVH 121 (4-6877826);S56CTX;39 | 
                RN0021 | 
                gmd | 
                 GDP-mannose-4,6-dehydratase | 
                Gmd | 
                GDP-Man | 
                GDP-4-keto-6-D-deoxymannose | 
                GDP-L-Col | 
                step4 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Col | 
                SynPath0009 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;40 | 
                none;40 | 
                RN0023 | 
                colA | 
                GDP-4-keto-6-deoxy-d-mannose 3-dehydrase | 
                ColA | 
                GDP-4-keto-6-D-deoxy-D-Man | 
                GDP-4-keto-3,6-D-dideoxy-D-Man | 
                GDP-L-Col | 
                step5 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Col | 
                SynPath0009 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;41 | 
                none;41 | 
                RN0024 | 
                colB | 
                GDP-colitose synthase | 
                ColB | 
                GDP-4-keto-3,6-D-dideoxy-D-Man | 
                GDP-L-Col | 
                GDP-L-Col | 
                step6-End | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-L-Col | 
                SynPath0009 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;42 | 
                none;42 | 
                RN0018 | 
                manA | 
                phosphomannose isomerase | 
                ManA | 
                Fru-6-P | 
                D-Man-6-P | 
                GDP-D-Rha | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha | 
                SynPath0010 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O7;43 | 
                RHB39-C23;NCTC11105;43 | 
                RN0019 | 
                manB | 
                phosphomannomutase | 
                ManB | 
                D-Man-6-P | 
                D-Man-1-P | 
                GDP-D-Rha | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha | 
                SynPath0010 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O7;44 | 
                RHB39-C23;NCTC11105;44 | 
                RN0020 | 
                manC | 
                mannose-1-phosphate guanylyltransferase | 
                ManC | 
                D-Man-1-P | 
                GDP-D-Man | 
                GDP-D-Rha | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha | 
                SynPath0010 | 
                
                    
                     
                    
                 | 
            
            
            
                | O11;O36;45 | 
                HVH 121 (4-6877826);S56CTX;45 | 
                RN0021 | 
                gmd | 
                GDP-mannose-4,6-dehydratase | 
                Gmd | 
                GDP-Man | 
                GDP-4-keto-6-D-deoxymannose | 
                GDP-D-Rha | 
                step4 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha | 
                SynPath0010 | 
                
                    
                     
                    
                 | 
            
            
            
                | O99;46 | 
                HUB1;E-1246;46 | 
                RN0025 | 
                rmd | 
                oxidoreductase | 
                Rmd | 
                GDP-4-keto-6-D-deoxymannose | 
                GDP-D-Rha | 
                GDP-D-Rha | 
                step5-End | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha | 
                SynPath0010 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;47 | 
                none;47 | 
                RN0018 | 
                manA | 
                phosphomannose isomerase | 
                ManA | 
                Fru-6-P | 
                D-Man-6-P | 
                GDP-D-Rha4NAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha4NAc | 
                SynPath0011 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O7;48 | 
                RHB39-C23;NCTC11105;48 | 
                RN0019 | 
                manB | 
                phosphomannomutase | 
                ManB | 
                D-Man-6-P | 
                D-Man-1-P | 
                GDP-D-Rha4NAc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha4NAc | 
                SynPath0011 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O7;49 | 
                RHB39-C23;NCTC11105;49 | 
                RN0020 | 
                manC | 
                mannose-1-phosphate guanylyltransferase | 
                ManC | 
                D-Man-1-P | 
                GDP-D-Man | 
                GDP-D-Rha4NAc | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha4NAc | 
                SynPath0011 | 
                
                    
                     
                    
                 | 
            
            
            
                | O11;O36;50 | 
                HVH 121 (4-6877826);S56CTX;50 | 
                RN0021 | 
                gmd | 
                 GDP-mannose-4,6-dehydratase | 
                Gmd | 
                GDP-D-Man | 
                GDP-4-keto-6-D-deoxymannose | 
                GDP-D-Rha4NAc | 
                step4 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha4NAc | 
                SynPath0011 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;51 | 
                none;51 | 
                RN0026 | 
                perA | 
                GDP-perosamine synthetase | 
                PerA | 
                GDP-4-keto-6-D-deoxymannose | 
                GDP-D-Rha4N | 
                GDP-D-Rha4NAc | 
                step5 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha4NAc | 
                SynPath0011 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;52 | 
                none;52 | 
                RN0027 | 
                perB | 
                GDP-perosamine N-acetyltransferase | 
                PerB | 
                GDP-D-Rha4N | 
                GDP-D-Rha4NAc | 
                GDP-D-Rha4NAc | 
                step6-End | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-D-Rha4NAc | 
                SynPath0011 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;53 | 
                none;53 | 
                RN0028 | 
                galU | 
                 UTP-glucose-1-phosphate uridylyltransferase  | 
                GalU | 
                Glc-1-P | 
                UDP-D-Glc | 
                UDP-D-Glc | 
                step1-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-Glc | 
                SynPath0012 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;54 | 
                none;54 | 
                RN0028 | 
                galU | 
                 UTP-glucose-1-phosphate uridylyltransferase  | 
                GalU | 
                Glc-1-P | 
                UDP-D-Glc | 
                UDP-D-Gal | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-Gal | 
                SynPath0013 | 
                
                    
                     
                    
                 | 
            
            
            
                | O22;O70;55 | 
                549;FWSEC0555;55 | 
                RN0029 | 
                galE | 
                UDP-glucose-4-epimerase | 
                GalE | 
                UDP-D-Glc | 
                UDP-D-Gal | 
                UDP-D-Gal | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-Gal | 
                SynPath0013 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;56 | 
                none;56 | 
                RN0028 | 
                galU | 
                 UTP-glucose-1-phosphate uridylyltransferase  | 
                GalU | 
                Glc-1-P | 
                UDP-D-Glc | 
                UDP-D-Galf | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-Galf | 
                SynPath0014 | 
                
                    
                     
                    
                 | 
            
            
            
                | O22;O70;57 | 
                549;FWSEC0555;57 | 
                RN0029 | 
                galE | 
                UDP-glucose-4-epimerase | 
                GalE | 
                UDP-D-Glc | 
                UDP-D-Gal | 
                UDP-D-Galf | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-Galf | 
                SynPath0014 | 
                
                    
                     
                    
                 | 
            
            
            
                | O16;O42;58 | 
                ER1821R;CETR2G40;58 | 
                RN0030 | 
                glf | 
                UDPgalactopyranose mutase | 
                Glf | 
                UDP-D-Gal | 
                UDP-D-Galf | 
                UDP-D-Galf | 
                step3-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-Galf | 
                SynPath0014 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;59 | 
                none;59 | 
                RN0028 | 
                galU | 
                 UTP-glucose-1-phosphate uridylyltransferase  | 
                GalU | 
                Glc-1-P | 
                UDP-D-Glc | 
                UDP-D-GlcA | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GlcA | 
                SynPath0015 | 
                
                    
                     
                    
                 | 
            
            
            
                | O101;O113;60 | 
                AR Bank #0346;blood-09-0249;60 | 
                RN0029 | 
                ugd | 
                UDP-glucose 6-dehydrogenase | 
                Ugd | 
                UDP-D-Glc | 
                UDP-D-GlcA | 
                UDP-D-GlcA | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GlcA | 
                SynPath0015 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;61 | 
                none;61 | 
                RN0028 | 
                galU | 
                 UTP-glucose-1-phosphate uridylyltransferase  | 
                GalU | 
                Glc-1-P | 
                UDP-D-Glc | 
                UDP-D-GalA | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalA | 
                SynPath0016 | 
                
                    
                     
                    
                 | 
            
            
            
                | O101;O113;62 | 
                AR Bank #0346;blood-09-0249;62 | 
                RN0029 | 
                ugd | 
                UDP-glucose 6-dehydrogenase | 
                Ugd | 
                UDP-D-Glc | 
                UDP-D-GlcA | 
                UDP-D-GalA | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalA | 
                SynPath0016 | 
                
                    
                     
                    
                 | 
            
            
            
                | O155;63 | 
                RHBSTW-00093;MS 115-1;63 | 
                RN0031 | 
                gla | 
                UDP-galacturonatenase | 
                Gla | 
                UDP-D-GlcA | 
                UDP-D-GalA | 
                UDP-D-GalA | 
                step3-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalA | 
                SynPath0016 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;64 | 
                none;64 | 
                RN0028 | 
                galU | 
                UTP-glucose-1-phosphate uridylyltransferase  | 
                GalU | 
                Glc-1-P | 
                UDP-D-Glc | 
                UDP-D-GalA6N | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalA6N | 
                SynPath0017 | 
                
                    
                     
                    
                 | 
            
            
            
                | O101;O113;65 | 
                AR Bank #0346;blood-09-0249;65 | 
                RN0029 | 
                ugd | 
                UDP-glucose 6-dehydrogenase | 
                Ugd | 
                UDP-D-Glc | 
                UDP-D-GlcA | 
                UDP-D-GalA6N | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalA6N | 
                SynPath0017 | 
                
                    
                     
                    
                 | 
            
            
            
                | O155;66 | 
                RHBSTW-00093;MS 115-1;66 | 
                RN0031 | 
                gla | 
                UDP-galacturonatenase | 
                Gla | 
                UDP-D-GlcA | 
                UDP-D-GalA | 
                UDP-D-GalA6N | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalA6N | 
                SynPath0017 | 
                
                    
                     
                    
                 | 
            
            
            
                | O65;67 | 
                E8V1A;B024ch;67 | 
                RN0032 | 
                wceT | 
                 | 
                WceT | 
                UDP-D-GalA | 
                UDP-D-GalA6N | 
                UDP-D-GalA6N | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalA6N | 
                SynPath0017 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;68 | 
                none;68 | 
                RN0028 | 
                galU | 
                 UTP-glucose-1-phosphate uridylyltransferase  | 
                GalU | 
                Glc-1-P | 
                UDP-D-Glc | 
                UDP-L-IdoA | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-IdoA | 
                SynPath0018 | 
                
                    
                     
                    
                 | 
            
            
            
                | O101;O113;69 | 
                AR Bank #0346;blood-09-0249;69 | 
                RN0029 | 
                ugd | 
                UDP-glucose 6-dehydrogenase | 
                Ugd | 
                UDP-D-Glc | 
                UDP-D-GlcA | 
                UDP-L-IdoA | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-IdoA | 
                SynPath0018 | 
                
                    
                     
                    
                 | 
            
            
            
                | O112ab;70 | 
                RHB18-C20;GZB8C114M;70 | 
                RN0033 | 
                gae | 
                C5-epimerase | 
                Gae | 
                UDP-D-GlcA | 
                UDP-L-IdoA | 
                UDP-L-IdoA | 
                step3-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-IdoA | 
                SynPath0018 | 
                
                    
                     
                    
                 | 
            
            
            
                | O118;O151;71 | 
                483;637;71 | 
                RN0034 | 
                rib | 
                ribulose 5-phosphate reductase/CDP-ribitol pyrophosphorylase | 
                Rib | 
                ribulose-5-P | 
                Ribitol-5-P | 
                CDP-D-Rib | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-CDP-D-Rib | 
                SynPath0019 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;72 | 
                none;72 | 
                RN0035 | 
                orf | 
                 | 
                Orf | 
                Ribitol-5-P | 
                CDP-D-Rib | 
                CDP-D-Rib | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-CDP-D-Rib | 
                SynPath0019 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;73 | 
                none;73 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-D-GlcNAc | 
                step1-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GlcNAc | 
                SynPath0020 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;74 | 
                none;74 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-D-ManNAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-ManNAc | 
                SynPath0021 | 
                
                    
                     
                    
                 | 
            
            
            
                | O1;O64;75 | 
                RUSPBB207;71.48;75 | 
                RN0037 | 
                mnaA | 
                UDP-Nacetylglucosamine-2-epimerase  | 
                MnaA | 
                UDP-D-GlcNAc | 
                UDP-D-ManNAc | 
                UDP-D-ManNAc | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-ManNAc | 
                SynPath0021 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;76 | 
                none;76 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-D-GalNAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAc | 
                SynPath0022 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O11;77 | 
                RHB39-C23;NCTC11105;77 | 
                RN0038 | 
                gne | 
                UDP-N-acetylglucosamine-4-epimerase | 
                Gne | 
                UDP-D-GlcNAc | 
                UDP-D-GalNAc | 
                UDP-D-GalNAc | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAc | 
                SynPath0022 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;78 | 
                none;78 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-D-GalNAcA | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAcA | 
                SynPath0023 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O11;79 | 
                RHB39-C23;NCTC11105;79 | 
                RN0038 | 
                gne | 
                UDP-N-acetylglucosamine-4-epimerase | 
                Gne | 
                UDP-D-GlcNAc | 
                UDP-D-GalNAc | 
                UDP-D-GalNAcA | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAcA | 
                SynPath0023 | 
                
                    
                     
                    
                 | 
            
            
            
                | O180;80 | 
                VREC0307;AG1;80 | 
                RN0039 | 
                gnaA | 
                UDP-GlcNAc 6-dehydrogenase | 
                GnaA | 
                UDP-D-GalNAc | 
                UDP-D-GalNAcA | 
                UDP-D-GalNAcA | 
                step3-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAcA | 
                SynPath0023 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;81 | 
                none;81 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-D-GalNAcAN | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAcAN | 
                SynPath0024 | 
                
                    
                     
                    
                 | 
            
            
            
                | O6;O11;82 | 
                RHB39-C23;NCTC11105;82 | 
                RN0038 | 
                gne | 
                UDP-N-acetylglucosamine-4-epimerase | 
                Gne | 
                UDP-D-GlcNAc | 
                UDP-D-GalNAc | 
                UDP-D-GalNAcAN | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAcAN | 
                SynPath0024 | 
                
                    
                     
                    
                 | 
            
            
            
                | O180;83 | 
                VREC0307;AG1;83 | 
                RN0039 | 
                gnaA | 
                UDP-GlcNAc 6-dehydrogenase | 
                GnaA | 
                UDP-D-GalNAc | 
                UDP-D-GalNAcA | 
                UDP-D-GalNAcAN | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAcAN | 
                SynPath0024 | 
                
                    
                     
                    
                 | 
            
            
            
                | O35;84 | 
                KS-P035;NX-C100;84 | 
                RN0040 | 
                wbpS | 
                aminotransferase | 
                WbpS | 
                UDP-D-GalNAcA | 
                UDP-D-GalNAcAN | 
                UDP-D-GalNAcAN | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-GalNAcAN | 
                SynPath0024 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;85 | 
                none;85 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-L-FucNAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAc | 
                SynPath0025 | 
                
                    
                     
                    
                 | 
            
            
            
                | O3;O4;86 | 
                498;M-C45;86 | 
                RN0041 | 
                fnlA | 
                4,6-dehydratase, 3- and 5-epimerase | 
                FnlA | 
                UDP-D-GlcNAc | 
                UDP-4-keto-L-arabino-HexNAc | 
                UDP-L-FucNAc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAc | 
                SynPath0025 | 
                
                    
                     
                    
                 | 
            
            
            
                | O4;O12;87 | 
                upec-105;EC_50;87 | 
                RN0042 | 
                fnlB | 
                reductase | 
                FnlB | 
                UDP-4-keto-L-arabino-HexNAc | 
                UDP-L-PneNAc | 
                UDP-L-FucNAc | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAc | 
                SynPath0025 | 
                
                    
                     
                    
                 | 
            
            
            
                | O4;O12;88 | 
                upec-105;EC_50;88 | 
                RN0043 | 
                fnlC | 
                C-2 epimerase  | 
                FnlC | 
                UDP-L-PneNAc | 
                UDP-L-FucNAc | 
                UDP-L-FucNAc | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAc | 
                SynPath0025 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;89 | 
                none;89 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-L-FucNAm | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAm | 
                SynPath0026 | 
                
                    
                     
                    
                 | 
            
            
            
                | O3;O4;90 | 
                498;M-C45;90 | 
                RN0041 | 
                fnlA | 
                4,6-dehydratase, 3- and 5-epimerase | 
                FnlA | 
                UDP-D-GlcNAc | 
                UDP-4-keto-L-arabino-HexNAc | 
                UDP-L-FucNAm | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAm | 
                SynPath0026 | 
                
                    
                     
                    
                 | 
            
            
            
                | O4;O12;91 | 
                upec-105;EC_50;91 | 
                RN0042 | 
                fnlB | 
                reductase | 
                FnlB | 
                UDP-4-keto-L-arabino-HexNAc | 
                UDP-L-PneNAc | 
                UDP-L-FucNAm | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAm | 
                SynPath0026 | 
                
                    
                     
                    
                 | 
            
            
            
                | O4;O12;92 | 
                upec-105;EC_50;92 | 
                RN0043 | 
                fnlC | 
                C-2 epimerase  | 
                FnlC | 
                UDP-L-PneNAc | 
                UDP-L-FucNAc | 
                UDP-L-FucNAm | 
                step4 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAm | 
                SynPath0026 | 
                
                    
                     
                    
                 | 
            
            
            
                | O118;O145;93 | 
                483;637;93 | 
                RN0044 | 
                wbuX,wbuY,wbuZ | 
                aminotransferase | 
                WbuX,WbuY,WbuZ | 
                UDP-L-FucNAc | 
                UDP-L-FucNAm | 
                UDP-L-FucNAm | 
                step5-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-FucNAm | 
                SynPath0026 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;94 | 
                none;94 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-L-RhaNAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-RhaNAc | 
                SynPath0027 | 
                
                    
                     
                    
                 | 
            
            
            
                | O3;O4;95 | 
                498;M-C45;95 | 
                RN0041 | 
                fnlA | 
                4,6-dehydratase, 3- and 5-epimerase | 
                FnlA | 
                UDP-D-GlcNAc | 
                UDP-4-keto-L-arabino-HexNAc | 
                UDP-L-RhaNAc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-RhaNAc | 
                SynPath0027 | 
                
                    
                     
                    
                 | 
            
            
            
                | O3;O98;96 | 
                498;M-C45;96 | 
                RN0047 | 
                qnlA | 
                dTDP-4-dehydrorhamnose reductase | 
                QnlA | 
                UDP-4-keto-L-arabino-HexNAc | 
                UDP-L-RhaNAc | 
                UDP-L-RhaNAc | 
                step3-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-RhaNAc | 
                SynPath0027 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;97 | 
                none;97 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-L-QuiNAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-QuiNAc | 
                SynPath0028 | 
                
                    
                     
                    
                 | 
            
            
            
                | O3;O4;98 | 
                498;M-C45;98 | 
                RN0041 | 
                fnlA | 
                4,6-dehydratase, 3- and 5-epimerase | 
                FnlA | 
                UDP-D-GlcNAc | 
                UDP-4-keto-L-arabino-HexNAc | 
                UDP-L-QuiNAc | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-QuiNAc | 
                SynPath0028 | 
                
                    
                     
                    
                 | 
            
            
            
                | O3;O98;99 | 
                498;M-C45;99 | 
                RN0047 | 
                qnlA | 
                dTDP-4-dehydrorhamnose reductase | 
                QnlA | 
                UDP-4-keto-L-arabino-HexNAc | 
                UDP-L-RhaNAc | 
                UDP-L-QuiNAc | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-QuiNAc | 
                SynPath0028 | 
                
                    
                     
                    
                 | 
            
            
            
                | O98;O163;100 | 
                FWSEC0102;FWSEC0369;100 | 
                RN0048 | 
                qnlB | 
                C-2 epimerase  | 
                QnlB | 
                UDP-L-RhaNAc | 
                UDP-L-QuiNAc | 
                UDP-L-QuiNAc | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-QuiNAc | 
                SynPath0028 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;101 | 
                none;101 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-FucNAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-FucNAc | 
                SynPath0029 | 
                
                    
                     
                    
                 | 
            
            
            
                | O22;O45;102 | 
                549;FWSEC0555;102 | 
                RN0049 | 
                wbhS,wbhP | 
                UDP-d-GlcNAc 4,6-dehydratase | 
                WbhS,WbhP | 
                UDP-D-GlcNAc | 
                UDP-FucNAc | 
                UDP-FucNAc | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-FucNAc | 
                SynPath0029 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;103 | 
                none;103 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-D-ManNAc3NAcA | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-ManNAc3NAcA | 
                SynPath0030 | 
                
                    
                     
                    
                 | 
            
            
            
                | O180;104 | 
                VREC0307;AG1;104 | 
                RN0051 | 
                gnaA | 
                UDP-GlcNAc 6-dehydrogenase | 
                GnaA | 
                UDP-D-GlcNAc | 
                UDP-D-GlcNAcA | 
                UDP-D-ManNAc3NAcA | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-ManNAc3NAcA | 
                SynPath0030 | 
                
                    
                     
                    
                 | 
            
            
            
                | O180;105 | 
                VREC0307;AG1;105 | 
                RN0052 | 
                mndA,mndB,mndC,mndD | 
                oxidoreductase,acetyltransferase,aminotransferase,UDP-N-acetylglucosamine 2-epimerase | 
                MndA,MndB,MndC,MndD | 
                UDP-D-GlcNAcA | 
                UDP-D-ManNAc3NAcA | 
                UDP-D-ManNAc3NAcA | 
                step3-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-D-ManNAc3NAcA | 
                SynPath0030 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;106 | 
                none;106 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-L-RhaNAc3NAc | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-RhaNAc3NAc | 
                SynPath0031 | 
                
                    
                     
                    
                 | 
            
            
            
                | O109;107 | 
                AMSHJX01;G17;107 | 
                RN0056 | 
                weiP/wekE,weiQ/wekF,weiS/wekG,weiO | 
                aminotransferase,aminotransferase,dehydratase/epimerase,acetyltransferase | 
                WeiP/WekE,WeiQ/WekF,WeiS/WekG,WeiO | 
                UDP-D-GlcNAc | 
                UDP-L-RhaNAc3NAc | 
                UDP-L-RhaNAc3NAc | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-RhaNAc3NAc | 
                SynPath0031 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;108 | 
                none;108 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                UDP-L-RhaNAc3NFo | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-RhaNAc3NFo | 
                SynPath0032 | 
                
                    
                     
                    
                 | 
            
            
            
                | O119;109 | 
                AMSHJX01;G17;109 | 
                RN0057 | 
                weiP/wekE,weiQ/wekF,weiS/wekG,wekD | 
                aminotransferase,aminotransferase,dehydratase/epimerase,ormyltransferase | 
                WeiP/WekE,WeiQ/WekF,WeiS/WekG,WekD | 
                UDP-D-GlcNAc | 
                UDP-L-RhaNAc3NFo | 
                UDP-L-RhaNAc3NFo | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-UDP-L-RhaNAc3NFo | 
                SynPath0032 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;110 | 
                none;110 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                CMP-8eLeg5Ac7Ac | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-8eLeg5Ac7Ac | 
                SynPath0033 | 
                
                    
                     
                    
                 | 
            
            
            
                | O61;O108;111 | 
                F2_71;K45V1;111 | 
                RN0061 | 
                elg1,elg2,elg5,elg3,elg6,elg4,elg7 | 
                UDP-N-acetylglucosamine 4,6-dehydratase,aminotransferase,acetyltransferase,UDP-N-acetylglucosamine 2-epimerase,sugar-phosphate nucleotide transferase,N-acetyl-neuraminic acid synthetase,cytidylyl-transferase | 
                Elg1,Elg2,Elg5,Elg3,Elg6,Elg4,Elg7 | 
                UDP-D-GlcNAc | 
                CMP-8eLeg5Ac7Ac | 
                CMP-8eLeg5Ac7Ac | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-8eLeg5Ac7Ac | 
                SynPath0033 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;112 | 
                none;112 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                CMP-Leg5Ac7Ala | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-Leg5Ac7Ala | 
                SynPath0034 | 
                
                    
                     
                    
                 | 
            
            
            
                | O161;113 | 
                N40513;48521;113 | 
                RN0068 | 
                lea1,lea2,lea3,lea5,lea6,lea4,lea7 | 
                C6 dehydratase,aminotransferase,alanyltransferase,UDP-Nacetylglucosamine 2-epimerase,sugar-phosphate nucleotide transferase,N-acetylneuraminic acid synthetase,CMP-N-acetylneuraminic acid synthetase | 
                Lea1,Lea2,Lea3,Lea5,Lea6,Lea4,Lea7 | 
                UDP-D-GlcNAc | 
                CMP-Leg5Ac7Ala | 
                CMP-Leg5Ac7Ala | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-Leg5Ac7Ala | 
                SynPath0034 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;114 | 
                none;114 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                CMP-Pse5Ac7Ac | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-Pse5Ac7Ac | 
                SynPath0035 | 
                
                    
                     
                    
                 | 
            
            
            
                | O136;115 | 
                8-3-DC15;08-00022;115 | 
                RN0075 | 
                psb1,psb2,psb4,psb6,psb3 | 
                C6 dehydratase/C5 epimerase,aminotransferase,nucleotidase,condensase,cytidylyltransferase | 
                Psb1,Psb2,Psb4,Psb6,Psb3 | 
                UDP-D-GlcNAc | 
                CMP-Pse5Ac7Ac | 
                CMP-Pse5Ac7Ac | 
                step2-End | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-Pse5Ac7Ac | 
                SynPath0035 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;116 | 
                none;116 | 
                RN0036 | 
                glmU | 
                UDP-N-acetyl-glucosamine pyrophosphorylase | 
                GlmU | 
                GlcNAc-1-P | 
                UDP-D-GlcNAc | 
                CMP-Neu5Ac | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-Neu5Ac | 
                SynPath0036 | 
                
                    
                     
                    
                 | 
            
            
            
                | O24;O56;117 | 
                VRES0558;FDAARGOS_1286;117 | 
                RN0080 | 
                nnaA | 
                UDP-N-acetylglucosamine-2-epimerase | 
                NnaA | 
                UDP-D-GlcNAc | 
                UDp-ManNAc | 
                CMP-Neu5Ac | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-Neu5Ac | 
                SynPath0036 | 
                
                    
                     
                    
                 | 
            
            
            
                | O24;O56;118 | 
                VRES0558;FDAARGOS_1286;118 | 
                RN0081 | 
                nnaB,nnaD | 
                N-acetylneuraminic acid synthetase,N-acetylneuraminic acid synthetase | 
                NnaB,NnaD | 
                UDp-ManNAc | 
                Neu5Ac | 
                CMP-Neu5Ac | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-Neu5Ac | 
                SynPath0036 | 
                
                    
                     
                    
                 | 
            
            
            
                | O24;O56;119 | 
                VRES0558;FDAARGOS_1286;119 | 
                RN0082 | 
                nnaC | 
                CMP-N-acetylneuraminic acid synthetase | 
                NnaC | 
                Neu5Ac | 
                CMP-Neu5Ac | 
                CMP-Neu5Ac | 
                step4-End | 
                Nucleotide-sugar biosynthesis | 
                S1-CMP-Neu5Ac | 
                SynPath0036 | 
                
                    
                     
                    
                 | 
            
            
            
                | O52;120 | 
                KTE171;1373;120 | 
                RN0083 | 
                gmhA | 
                Glyceromannoheptose-7-P isomerase | 
                GmhA | 
                Sedoheptulose-7-P | 
                D-Hep-7-P | 
                GDP-6d-D-manHe | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-6d-D-manHep | 
                SynPath0037 | 
                
                    
                     
                    
                 | 
            
            
            
                | O52;121 | 
                KTE171;1373;121 | 
                RN0084 | 
                hddA | 
                D-Heptose 7-phosphate kinase | 
                HddA | 
                D-Hep-7-P | 
                D-Hep-1,7-PP | 
                GDP-6d-D-manHe | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-6d-D-manHep | 
                SynPath0037 | 
                
                    
                     
                    
                 | 
            
            
            
                | O52;122 | 
                KTE171;1373;122 | 
                RN0085 | 
                gmhB | 
                D-Heptose 1,7-biphosphate phosphatase | 
                GmhB | 
                D-Hep-1,7-PP | 
                D-Hep-1-P | 
                GDP-6d-D-manHe | 
                step3 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-6d-D-manHep | 
                SynPath0037 | 
                
                    
                     
                    
                 | 
            
            
            
                | O52;123 | 
                KTE171;1373;123 | 
                RN0086 | 
                hddC | 
                D-Heptose 1-phosphate guanosyltransferase | 
                HddC | 
                D-Hep-1-P | 
                GDP-D-glycero-D-manno-Heptose | 
                GDP-6d-D-manHe | 
                step4 | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-6d-D-manHep | 
                SynPath0037 | 
                
                    
                     
                    
                 | 
            
            
            
                | O52;124 | 
                KTE171;1373;124 | 
                RN0087 | 
                dmhA,dmhB | 
                NAD-dependentepimerase/dehydratase | 
                DmhA | 
                GDP-D-glycero-D-manno-Heptose | 
                GDP-6d-D-manHep | 
                GDP-6d-D-manHe | 
                step5-End | 
                Nucleotide-sugar biosynthesis | 
                S1-GDP-6d-D-manHep | 
                SynPath0037 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;125 | 
                none;125 | 
                RN0088 | 
                neuC | 
                none | 
                NeuC | 
                UDP-GlcNAc | 
                UDP-ManNAc | 
                CMP-Neu5Ac | 
                step1 | 
                Nucleotide-sugar biosynthesis | 
                S2-CMP-Neu5Ac | 
                SynPath0038 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;126 | 
                none;126 | 
                RN0089 | 
                neuB | 
                none | 
                NeuB | 
                UDP-ManNAc | 
                Neu5Ac | 
                CMP-Neu5Ac | 
                step2 | 
                Nucleotide-sugar biosynthesis | 
                S2-CMP-Neu5Ac | 
                SynPath0038 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;127 | 
                none;127 | 
                RN0090 | 
                neuA | 
                none | 
                NeuA | 
                Neu5Ac | 
                CMP-Neu5Ac | 
                CMP-Neu5Ac | 
                step3-End | 
                Nucleotide-sugar biosynthesis | 
                S2-CMP-Neu5Ac | 
                SynPath0038 | 
                
                    
                     
                    
                 | 
            
            
            
                | none;128 | 
                none;128 | 
                RN0091 | 
                tagD | 
                none | 
                TagD | 
                Gro-1-P | 
                CDP-Gro | 
                CDP-Gro | 
                step1-End | 
                 | 
                S1-CDP-Gro | 
                SynPath0039 | 
                
                    
                     
                    
                 |