LOCUS       AB812085               20197 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli genes for O-antigen biosynthetic locus, partial
            sequence, strain: Su3972-41.
ACCESSION   AB812085
VERSION     AB812085.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 20197)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-APR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..20197
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="Su3972-41"
                     /db_xref="taxon:562"
                     /note="serogroup:O54"
     gene            <1..892
                     /gene="wcaM"
     CDS             <1..892
                     /gene="wcaM"
                     /codon_start=2
                     /transl_table=11
                     /product="colanic acid biosynthesis protein"
                     /protein_id="BAQ02111.1"
                     /translation="RQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDHVI
                     ERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGTDCRQLIHVENGKHF
                     VIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGKYL
                     SIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKPQHLF
                     MRNIKVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNERGQSSVDIDR
                     VNHHIVNVEKINFRLPERRE"
     gene            1055..1960
                     /gene="galF"
     CDS             1055..1960
                     /gene="galF"
                     /note="O054_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ02112.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2332..3417
                     /gene="rmlB"
     CDS             2332..3417
                     /gene="rmlB"
                     /note="O054_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ02113.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     DVSDSERYVFEHADICDAAVMARVFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDGDKKNSFRFHHISTDEVYGDLPHPDEVNNTEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KTLPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKISRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRQ"
     gene            3417..4316
                     /gene="rmlD"
     CDS             3417..4316
                     /gene="rmlD"
                     /note="O054_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ02114.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNSAAHTAVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHY
                     STDYVFPGTGEIPWQEADATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAS
                     GTTTWHDYAALVFEEARKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            4374..5249
                     /gene="rmlA"
     CDS             4374..5249
                     /gene="rmlA"
                     /note="O054_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ02115.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPTPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDAAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNGVVEMAKNLKPSARGELEITDINRIYMEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDSEQVKVLAEPL
                     KKNAYGQYLIKLTQG"
     gene            5253..6311
                     /gene="wzy"
     CDS             5253..6311
                     /gene="wzy"
                     /note="O054_05"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="BAQ02116.1"
                     /translation="MESLFIYFFVTMVLIVFTCFFKHNNNILIIVCSAILSVTYGLRV
                     GIGNDYEQYNNIFNAINYNSYSAIEPTFILLSRLLEQYDYGFNYLMAIYAFVTFFLCY
                     MGIRKYNIYPYVPLLMFSTGFIFFVDNQVRQALATSFFIYYMRFISTREFGKYLICVI
                     ISTIFMHFSSAVLLLAYFVTRKRINGVVWILLLLFAYILMKLDVVHTVLSNIISMVPY
                     YSELYLQRFNDISLNVTGSGLGVLFWLIIAVFIVIFNQKNDDVIVFNLFIIGTIINTI
                     FINYDIFERVSFYFIYLRFILLAIIFKKIMFRNNVNFMLCGILITLTVFFTSYEVIND
                     ANKHGVVPLRFIYLDTEV"
     CDS             6314..7132
                     /note="O054_06"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ02117.1"
                     /translation="MDKIAVIMSVYNGDLPQNVELAIDSILNQRYKNYKLFIMIDGPV
                     AQNILMILRKYEQEPAIEIYSRDINKGLATSLNELIDIIKSKNDYNFIARMDSDDESL
                     PDRFCEQINYLQKAPHIDVVGSFCHEFGAEFALDIKRVPLEHEELKKYTLYKCPFIHP
                     TVMFRISVFNDAQIRYPTNTKLSEDLALWFLLLSRGYKFANIDKVLLNYRIDDATLSR
                     RSGVKKAFSEMNIRFLYSLKMKNFSVFIYSLILIRGVLALCPLKLKKIVYKKFR"
     CDS             7129..7905
                     /note="O054_07"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ02118.1"
                     /translation="MRKRVVYTAIFGGYDNLIDPKEIDKSVDYICFTDDKNIKSHKWN
                     VIYVKTDEEIDKAKLNRHYKFFPHLYFSEYEESLYLDGNIEIVSERISEAFDIALNDS
                     DISIPRHTERNCIYEEANTCLELGKGNSEKIKEQIEFYKHSDYPENNGLFENNVIFRK
                     HNTQAIIKLMEEWHDAISIFSARDQLSLCFLMWKNSICCKEFSWGPKKSNRFFKIRFH
                     RAEINNPFYKKIILYILLNKNIKWYYYTMSLIINKLKRMV"
     CDS             7902..8519
                     /note="O054_08"
                     /codon_start=1
                     /transl_table=11
                     /product="putative hydrolase"
                     /protein_id="BAQ02119.1"
                     /translation="MKKAIVDVCYTLYSRNTTFAFIDYVLLRKFNKKSYLANKYLKFF
                     LVGIGKIVKRDLYRRFYIRHLKGFKKIDLKELAQDFYYDVLDENKIKAVFSLLEKNKN
                     DYKFILCSASLDIIVEAIISNNYMFESKFYSSQLRFVDDVCEGVLDKDLLGYKHQHIG
                     EIDWVITDNKSDLELVKRAKTSTIIAKNKHVCFWNKNGIEVDIII"
     CDS             8516..9301
                     /note="O054_09"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ02120.1"
                     /translation="MIQILFFLPFVYTFTTRLNDRKKRIAWCFTYIIPVFMAFAYIMP
                     ENIGHNIIYFIMSILVIYSAYELGYFYNDAELIKKEDKPTLRLNLEQMIFYQKYRGFI
                     YCIRVVLITILCMAMVQLNYEIGISLILAVSIILITYVFYNSTRSKWNIPLYSFLVFI
                     RYFGIFIYFTSIKSLFYLWLAYPLCVTIEFMSKPRFKIPLYLVKNNTDLFRVYYYIVL
                     SFLLLLMNYKDCVPFFINLIVGYFFFFRTLTYFTISKKYRGVN"
     CDS             9301..10158
                     /note="O054_10"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ02121.1"
                     /translation="MKGYAAVIVTFYPDKEHVKSMYHALADQVEYIITVDNTPMHVME
                     TVQHDNNYKIYLGDNLGIATAQNVGLRKAIELGCKKCIIFDQDSIIPESICQTLGNDI
                     DTLNSMGMKVACIGPRINDILEKKIEKSKNEIKVVNNCFSVNQIIASGSLFNLEFLED
                     IGYMEDDLFIDAVDHEWCWRAKKNGYDVCISANIYMQHVIGIDRDNFLFWTYIVCSPI
                     RHYYQFRNSLLLLSRDYVPTKWKIKKCIEILFLPIIFSIKGPERMARLGYMIKGLLNG
                     LLGNVGRMR"
     gene            10155..11405
                     /gene="wzx"
     CDS             10155..11405
                     /gene="wzx"
                     /note="O054_11"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="BAQ02122.1"
                     /translation="MILAKVKNIYLVNKKIFESISYLAIIQMVAMILTFLTYPYLIKV
                     LGLGLYGKIMLSQAVVSYVAIFVNFGFNISAAKSASEKINKPEQLNEICSAIIIAKTL
                     IWLFITFIYVICILQFVPDNKNKVLYLSAYTLTFNEFLVCQWFYQAIEELKIIATLSI
                     ISKVTNVILIFLLVKSPSNYYFVSLITGGAYFFTGVYSILHMFRHHIKFVVPSISVII
                     NVTKDSFNLFLTSAIIAIKNKLDVILIGAFISSEMVAIYDFAQKILNILLLPITIISN
                     ATFPRMNREKNKIFLKKIILVSFGLTFIYITFSELLLPYIMHYIFVVSHDSINITRLM
                     ILSAIFLSLSLPLAQNGLIVFNYTKLHLLGMLSTTALYIGIMALGYKCSLLTDVYYFV
                     YTSLILFAYEAFYRYSFCKWKRIL"
     gene            13220..13774
                     /gene="rmlC"
     CDS             13220..13774
                     /gene="rmlC"
                     /note="O054_12"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ02123.1"
                     /translation="MEQKMKVINTFINGLKIIEPQVHMDNRGFFLETYSEEKYCELIG
                     RELHFVQDNHSRSTKGVLRGLHFQSKHPQGKLVRVTRGIVFDVAVDLRINSQTFGKWF
                     GIILSEDNKRQLWLPEGFAHGFQVLSDIADFEYKCTDYYYPEFERTLLWNDADVNISW
                     PLALSIISEKDKRGHSLSEIKSYI"
     gene            13916..15322
                     /gene="gnd"
     CDS             13916..15322
                     /gene="gnd"
                     /note="O054_13"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ02124.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEEGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQSAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            15571..16737
                     /gene="ugd"
     CDS             15571..16737
                     /gene="ugd"
                     /note="O054_14"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ02125.1"
                     /translation="MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSP
                     IVDKEIEEYLASKDLNFRATTDKFDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIR
                     DVTEINPNAVMIIKSTIPVGFTESIKERFGVENVIFSPEFLREGKALYDNLHPSRIVI
                     GEQSERAERFAALLQEGAIKQDIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGVPVIV
                     YEPAMKEDDFFRSRVVRDLDAFKQEADVIISNRMSADLTDVADKVYTRDLFGND"
     CDS             complement(16803..17807)
                     /note="O054_15"
                     /codon_start=1
                     /transl_table=11
                     /product="putative nucleotide sugar epimerase"
                     /protein_id="BAQ02126.1"
                     /translation="MKFLVTGAAGFIGFYVSKRLLAAGHQVVGIDNLNDYYDVNLKQA
                     RLDLLKHDNFSFYKIDLADREKMAALFVDERFERVINLAAQAGVRYSLENPNAYADAN
                     LIGFLNILEGCRHNNIQHLLYASSSSVYGMNRKMPFSTDDSVDHPVSLYAATKKANEL
                     MAHTYSHLYGLPTTGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNFGKMKRDFT
                     YIDDIAEAIIRLQDVIPEKDPQWAVETGSPATSSAPYRVYNIGNSSPVELMDYINALE
                     EALGIEANKNMMPLQPGDVLETSADTKALYDVIGFKPETSVKEGVKNFVEWYRNFYKV
                     "
     gene            18159..19193
                     /gene="wzz"
     CDS             18159..19193
                     /gene="wzz"
                     /note="O054_16"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ02127.1"
                     /translation="MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLVVAKEKWTSTAIVTQPDVGQIAGYNNAINVIYGS
                     AAPKVSEIQSMLIGRFSTTFSALAETLDNQEEPEKLTIEPTVKNQSLPLAVSYVGETP
                     EGAQKQLAKYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQIQQTQDVTQDTMFLLGSEALEAMIKHEATRPLVFSSSYYQT
                     RQNLLDIDNLDVDKLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     gene            complement(19289..19900)
                     /gene="hisI"
     CDS             complement(19289..19900)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ02128.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNITPDCDNDTLLLLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSANPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
ORIGIN      
        1 acgccaggga tttcataacc agattatcgg tgccaacatc accaattgta agttcagcga
       61 cttacaaggc gacgccattg aatggaacgt ggcaattaac gacagtgata ttttgatctc
      121 cgaccatgtc atcgagcgca tcaactgtac caacggcaaa atcaactggg gaatcggcat
      181 aggccttgcg ggaagtacct acgataataa ctacccggaa gaccaggcag tgaaaaactt
      241 tgtcgtggcg aatatcacgg ggacggattg tcggcagttg atacatgttg aaaatggtaa
      301 acattttgtt attcgtaata tcaaagcccg caatatcacg ccggatttca gtaagaaagc
      361 aggtattgat aacgccacag tcgctattta cggttgtgac aatttcgtga ttgataatat
      421 tgaaatgatt aatagcgccg ggatgttaat cggctatggg gtaattaaag gcaaatatct
      481 ctcgataccg caaaatttcc gagtgaataa tattcaactg gataataccc accttgctta
      541 caaattgcgc ggtatccaaa tctccgccgg gaatgctgtc tcctttgtgg cactgactaa
      601 cattgagatg aagcgtgcct cgctggagct tcacaataaa ccgcaacatc tttttatgcg
      661 aaatatcaaa gtgatgcagg aatcctctgt tggacccgca ttgagcatga acttcgacat
      721 gcgcaaagac gttcgcggcg tctttatggc gaaaaaagaa acactgctgt ctcttgcaaa
      781 tgttcatgcg gtgaatgaaa gagggcaaag ctccgtcgat atcgacaggg ttaatcacca
      841 tattgttaat gtggaaaaga ttaactttag attgccggaa cggagagagt agatttgcga
      901 ccattcctgg aaaaatggag ccatacttag gaacaatgct actgcaatcc acaacgaagc
      961 ggcgtaacat cacaagtaat tcagtaatca attcagggta attgatgctg gcgaaaaaaa
     1021 tcgaacaagc tataattcag caaccatttt acaggtggat gaaataatga cgaatttaaa
     1081 agcagttatt cctgtagcgg gtcttgggat gcatatgttg cctgccacta aggcgattcc
     1141 caaagagatg ctaccgatcg tcgacaagcc aatgattcag tatattgttg acgagattgt
     1201 ggctgcaggg atcaaagaaa tcctcctggt aactcatgcg tccaagaacg cggtcgaaaa
     1261 ccacttcgac acctcttatg aattagaatc tcttcttgag cagcgcgtga agcgtcaact
     1321 actggcggaa gttcagtcca tctgcccgcc gggcgtgacc attatgaacg tacgtcaggg
     1381 cgaaccttta ggtttaggtc actccatttt gtgtgcacga cccgccattg gtgacaaccc
     1441 atttgtcgtg gtgctgccag acgttgtgat cgacgacgcc agtgccgatc cgctgcgtta
     1501 caaccttgct gccatgattg cgcgtttcaa cgaaacgggc cgcagccagg tgctggcaaa
     1561 acgtatgccg ggtgacctct ctgaatactc cgtcattcag accaaagaac cgctggatcg
     1621 cgaaggcaaa gtcagccgca ttgttgaatt tatcgaaaaa ccggatcagc cgcagacgct
     1681 ggactcagac atcatggccg ttggtcgcta tgtgctttct gcagatattt ggccggaact
     1741 tgaacgcact cagcctggtg catgggggcg tattcagctg actgatgcca tcgctgaact
     1801 ggcgaaaaaa cagtccgttg atgccatgct gatgacaggt gacagctacg actgcggtaa
     1861 aaaaatgggt tatatgcaag cgttcgtgaa gtatgggctg cgcaacctga aagaaggggc
     1921 gaagttccgt aaaggcattg agaagctgtt aagcgaataa tgaaaatctg accggatgta
     1981 acggttgata agaaaattat aacggcagtg aagattcgtg gcgaaagtaa tttgttgcga
     2041 attttcctgc cgttgttata tataaacaat cagaataaca acgagttagc aataggattt
     2101 tagtcaaagt tttccaggat tttccttgtt tccagagcgg attggtaaga caattagcgt
     2161 ttgaattttt cgggtttagc gcgagtgggt aacgctcgtc acatcgtagg catgcatgca
     2221 gtgctctggt agctgtaaag ccaggggcgg tagcgtgcat taatacctct attaatcaaa
     2281 ctgagagctg cttatttcac agcatgctct gaagtaatat ggaataaaaa agtgaagata
     2341 cttgttactg gtggcgcagg atttattggt tctgctgtag ttcgtcacat tataaataat
     2401 acgcaggata gtgttgttaa tgtcgataaa ttaacgtacg ccggaaacct ggaatcactt
     2461 gctgatgttt ctgattccga acgctatgtt tttgaacatg cggatatttg cgatgcagct
     2521 gtaatggcac gggtttttgc tcagcatcag ccggatgcag tgatgcacct ggcagctgaa
     2581 agccatgttg accgttcaat tacaggccct gcggcattta ttgaaaccaa tattgttggt
     2641 acttatgtcc ttttagaggc cgctcggaat tactggtctg ctcttgatgg cgacaagaaa
     2701 aatagcttcc gttttcatca tatttctact gacgaagtct atggtgattt gcctcatcca
     2761 gatgaagtaa ataatacaga agaattaccc ttatttactg agacgacagc ttacgcgcca
     2821 agcagccctt attccgcatc caaagcatcc agcgatcatt tagtccgcgc gtggaaacgt
     2881 acctatggtt taccgaccat tgtgactaat tgctctaaca attatggtcc ttatcatttc
     2941 ccggaaaaat taattccact agtaattctt aatgctctgg aaggtaaaac attacctatt
     3001 tatggtaaag gggatcaaat tcgcgactgg ttgtatgttg aagatcatgc gcgtgcgtta
     3061 tataccgtcg taaccgaagg taaagcgggt gaaacttata acattggtgg acacaacgaa
     3121 aagaaaaaca tcgatgtagt gctcactatt tgtgatttgt tggatgagat tgtaccgaaa
     3181 gagaaatctt atcgtgagca aatcacttat gttgccgatc gtccgggaca cgatcgccgt
     3241 tatgcgattg atgctgagaa gattagccgc gaattgggat ggaaaccaca ggaaacgttt
     3301 gagagcggga ttcggaagac agtggaatgg tacctgtcca atacaaaatg ggttgataat
     3361 gttaaaagtg gtgcctatca atcgtggatt gaacagaact atgagggtcg ccagtaatga
     3421 atatcctcct ttttggcaaa acagggcagg taggttggga actacagcgt gctctggcac
     3481 ctctggggaa tttgattgct cttgatgttc actccactga ttactgtggt gattttagta
     3541 atcctgaagg tgtagctgaa accgtaagaa gcattcggcc tgatattatt gtcaactcag
     3601 ccgctcacac cgcagtagac aaagcagaat cagaaccgga gtttgcacaa ttacttaacg
     3661 cgacgagtgt cgaagcgatc gcgaaagcag ccaatgaagt cggcgcctgg gttattcact
     3721 actctactga ctacgtattt ccggggaccg gtgaaatacc atggcaggag gcggatgcaa
     3781 ccgcaccgct aaatgtttac ggtgaaacca agttagctgg agaaaaagca ttacaagagc
     3841 attgtgcgaa gcacctaatt ttccgtacca gctgggtcta tgcaggtaag ggaaataact
     3901 tcgccaaaac gatgttgcgt ctggcaaaag agcgtgaaga attagccgtt attaatgatc
     3961 agtttggtgc gccaacaggt gctgaactgc tggctgattg tacggcacat gccattcgtg
     4021 tggcactgaa taaaccagaa gtcgcaggct tgtaccatct ggtagccagt ggtaccacaa
     4081 cctggcacga ttatgctgcg ctggtttttg aagaggcacg aaaagcaggt attccccttg
     4141 cactcaacaa gctcaacgca gtaccaacaa cagcctatcc tacaccagct cgtcgtccac
     4201 ataactctcg ccttaataca gaaaaatttc agcagaactt tgcgcttgtc ttgcctgact
     4261 ggcaggttgg tgtgaaacga atgctcaacg aattatttac gactacagca atttaatagt
     4321 ttttgcatct tgttcgtgat ggtggagtaa gatgaattaa aaggaatgat gaaatgaaaa
     4381 cgcgtaaagg tattatttta gcgggcggtt ctggtacacg tctttatcct gtgactatgg
     4441 ctgtcagtaa acagctatta cctatttatg ataaaccgat gatctattac ccgctctcta
     4501 cactgatgtt agcgggtatt cgtgatattc tgattattag tacgccacag gatactcctc
     4561 gttttcaaca actgctgggt gacggtagcc agtgggggct aaatcttcag tacaaagtgc
     4621 aaccgactcc agatgggctt gcgcaggcat ttatcatcgg tgaagagttt atcggtggtg
     4681 atgattgtgc tttggttcta ggtgataaca tcttttacgg tcacgatctg ccgaagttaa
     4741 tggatgccgc tgttaacaaa gaaagtggtg caacggtatt tgcctatcac gttaatgatc
     4801 ctgaacgcta cggtgtcgta gagtttgata aaaacggtac ggcaattagc ctggaagaaa
     4861 aaccgttaca accaaagagt aattatgcgg taaccgggct ttatttctat gataacggcg
     4921 ttgtggaaat ggcgaaaaac cttaagcctt ctgcccgtgg tgaactagaa attaccgata
     4981 ttaaccgtat ctatatggag caggggcgtt tatccgttgc catgatggga cgtggttatg
     5041 catggctgga cacggggaca catcaaagtc ttattgaagc aagcaacttc attgcaacaa
     5101 ttgaagaacg tcaggggctg aaagtatcct gcccggaaga aattgcttac cgtaaaggat
     5161 ttattgattc tgagcaggtc aaagtattag ctgaaccgct gaaaaaaaat gcttatggtc
     5221 agtacttaat caaattgaca cagggataat aaatggaatc tctattcatt tatttttttg
     5281 ttacaatggt gttaattgtt tttacgtgtt tttttaaaca taataataat atattgataa
     5341 ttgtttgtag tgctatatta tctgttacat atgggctacg tgttggaata ggtaatgatt
     5401 atgaacaata caataacata ttcaacgcaa ttaattataa ctcctattct gcaatagaac
     5461 cgacatttat attgctatcc agattgctgg aacagtatga ttatggcttt aattatctaa
     5521 tggcaatata tgcgtttgtg actttttttc tttgttatat ggggataaga aaatataata
     5581 tctatcctta tgtgccattg ttaatgtttt ctaccggttt tatatttttt gtggataacc
     5641 aagtaaggca agcactggca acatcgtttt ttatctatta tatgcggttt atatcgacaa
     5701 gggaatttgg gaaatatttg atatgtgtga taatatcaac tatttttatg catttcagtt
     5761 cagcggtttt attgcttgcg tactttgtaa ctagaaagcg aataaatgga gtagtttgga
     5821 ttttattatt gttgtttgct tatattttaa tgaagttgga cgtggtccac accgtattat
     5881 ccaatattat aagcatggtg ccgtactatt cagaactcta tttgcaacgg tttaatgata
     5941 taagtctgaa cgtaactggt agtggattag gtgtattgtt ctggttgata atagctgtat
     6001 tcattgtaat ttttaatcaa aaaaatgatg atgttattgt ctttaattta tttataattg
     6061 gtacaataat caatacgatt tttattaatt atgatatatt tgagcgcgtt agtttttatt
     6121 ttatttattt aaggtttatt ctattggcaa ttatttttaa aaaaataatg tttagaaata
     6181 atgttaattt tatgctttgt gggattctaa tcactttaac tgtgtttttt actagctatg
     6241 aggtgataaa tgatgctaat aaacatgggg tggtaccttt aagattcatt tatttagata
     6301 ccgaggtata atcatggaca agatagctgt tattatgagt gtctataacg gagatctacc
     6361 tcagaatgta gaacttgcaa ttgatagtat tttaaatcaa aggtataaaa attataagtt
     6421 atttataatg attgatgggc ctgttgctca aaatattctg atgatattaa gaaaatatga
     6481 gcaagagcct gcaattgaga tatattcacg tgatataaat aaaggattag caacttcctt
     6541 aaatgaattg attgatatta taaaaagtaa aaacgattat aactttattg cacgaatgga
     6601 tagtgatgac gagtcattac ctgatcggtt ttgtgagcag ataaattatc tgcaaaaagc
     6661 gccacatatt gacgttgttg gtagtttttg ccatgaattt ggggctgagt ttgcgttgga
     6721 tattaaaagg gttcctttag aacatgagga actaaagaaa tatacattat acaaatgccc
     6781 atttattcat ccaacggtta tgtttagaat atcagttttt aacgacgctc agatcagata
     6841 cccaactaat actaaactga gtgaagattt agccttatgg tttctattac tttctcgtgg
     6901 ttacaaattt gcaaatatag ataaagtatt attaaactat agaattgatg atgctacgct
     6961 gtcacgacgt tctggggtga agaaagcatt tagtgaaatg aatattagat ttctttattc
     7021 acttaagatg aaaaattttt ccgtatttat ttattcgttg attcttatcc ggggggtact
     7081 tgcactatgt ccactaaaat taaaaaaaat agtatacaaa aagtttcgat gagaaaaaga
     7141 gttgtatata ccgcaatttt tggtggttat gataatttga tagatccaaa agaaattgat
     7201 aagtcggttg attatatctg tttcacagat gacaaaaata taaaatcaca taaatggaat
     7261 gtgatatatg ttaaaactga tgaggaaatt gataaagcaa agttaaacag gcattacaaa
     7321 ttttttcctc acctgtactt ttcagaatat gaggaaagct tgtacctcga tggtaatatt
     7381 gaaatagtca gtgaaagaat ctctgaggca tttgatattg cactcaatga ttctgacatt
     7441 tcaataccaa gacacactga aagaaactgc atttatgaag aagcaaacac atgtttagaa
     7501 ctcgggaaag gtaattcaga gaaaataaaa gaacaaatag aattttataa gcatagcgac
     7561 tatccagaaa ataatggtct gtttgaaaat aatgttatct tcagaaagca taatacgcaa
     7621 gcaataataa agttaatgga agaatggcat gatgctatat caatattttc tgccagagat
     7681 cagctgagtc tttgttttct aatgtggaaa aattctatat gttgcaaaga gttttcatgg
     7741 ggaccgaaaa aatcaaatag attctttaaa atcagatttc atcgagccga aattaataat
     7801 ccattctaca agaagataat tttatatata ttactgaata aaaatattaa gtggtactat
     7861 tatactatga gtctgataat taacaaatta aagaggatgg tatgaaaaaa gcgattgtag
     7921 atgtttgcta cactctttat tcacgtaata caacgtttgc atttattgat tatgtgttgt
     7981 tgagaaaatt caataaaaaa agctatttag ctaataaata tttaaagttt tttttagttg
     8041 gtattggtaa aattgtaaaa agagatctat atagaagatt ttatataagg catttgaaag
     8101 ggtttaaaaa aatagattta aaagaactag ctcaggattt ttattatgat gttcttgatg
     8161 aaaacaaaat caaagcagtt ttttctcttc tagaaaaaaa taaaaatgat tacaaattta
     8221 tattatgttc tgcgtcatta gatataatag ttgaggcaat tatttcaaat aattatatgt
     8281 ttgagtcgaa attttactct agtcaattaa gatttgttga tgacgtttgt gaaggcgttc
     8341 ttgataaaga tcttttaggt tataaacacc aacatattgg agaaatagat tgggtaataa
     8401 ctgataataa atcagatctt gaactggtta agcgtgcgaa aacatcgaca attattgcaa
     8461 aaaacaaaca tgtgtgtttc tggaacaaaa atggtatcga ggtggacata attatatgat
     8521 tcaaatacta ttttttcttc cttttgtata tacatttact acaagactta atgacagaaa
     8581 aaagcgtatt gcatggtgct ttacttatat aatccctgtc ttcatggctt ttgcatatat
     8641 aatgccagaa aatatcggac ataatattat atattttata atgtctattc ttgtaatata
     8701 ttcagcatat gagctcggat atttttataa tgatgcagag ttaattaaaa aagaggataa
     8761 gcctactctg agattgaact tggaacaaat gattttttat caaaaatatc gtggttttat
     8821 atattgtatc cgggtagtgt taatcaccat actctgcatg gctatggtac aacttaatta
     8881 tgagattggg atttcattaa tcttggctgt atctatcata ttaataacat atgtatttta
     8941 taattcaaca aggagtaaat ggaatatccc actgtacagt tttctggttt ttataaggta
     9001 ttttgggatt tttatctatt ttaccagcat caagtcgctt ttttatttgt ggttggcata
     9061 tccgctatgt gtaacaatag agttcatgtc aaagcctaga tttaaaatac ctctttatct
     9121 tgtgaaaaat aataccgatc tgttccgtgt gtattattat attgttttat ctttcctttt
     9181 attactcatg aattataaag attgtgttcc tttttttata aatttaattg tgggttattt
     9241 tttctttttt agaacattaa cctattttac tatttcaaaa aaatatagag gtgtaaatta
     9301 atgaaaggat acgcggctgt aattgttact ttttatcctg acaaagagca tgttaagtcg
     9361 atgtatcatg cacttgcaga tcaagttgag tacattatta cggttgataa tacacctatg
     9421 catgtaatgg agactgtaca gcatgataat aattataaaa tatatttagg agataattta
     9481 ggaattgcaa cggcacaaaa tgttggcttg aggaaagcta ttgagttggg ctgcaaaaaa
     9541 tgtataattt tcgatcaaga ttcaataata cctgaaagta tttgtcaaac tcttggtaat
     9601 gatattgata ctcttaatag tatgggaatg aaagttgcct gtattggacc tcgaattaat
     9661 gatattctag aaaagaaaat cgagaagtca aaaaatgaaa taaaagttgt taataattgt
     9721 ttttcagtaa atcaaattat tgcgtccggt tctttattca atttggagtt tcttgaagat
     9781 attggctata tggaggatga tttatttata gatgctgtag atcatgaatg gtgttggaga
     9841 gccaaaaaaa atggttacga tgtctgtata tctgccaaca tatatatgca acatgttata
     9901 ggtatagata gagataattt tcttttttgg acgtatattg tgtgctctcc tataagacat
     9961 tattatcaat ttaggaattc tctccttctt ttgtcaagag attatgtacc gacaaaatgg
    10021 aaaataaaaa aatgtattga aatattattt cttccgataa ttttttcaat aaaaggtcct
    10081 gaaaggatgg ctagactagg ctatatgatt aaaggattat taaatgggct ccttggcaat
    10141 gtaggaagaa tgagatgatt ttagctaagg tgaaaaatat ttacttagta aataaaaaga
    10201 tttttgagag catatcgtat ctggctatca tacaaatggt agcgatgatt ttaacctttt
    10261 taacgtatcc ttatttaata aaagttcttg gtttaggatt gtatgggaaa attatgctaa
    10321 gccaagctgt agttagttat gtagccatat ttgttaattt tggatttaat attagcgctg
    10381 cgaaatctgc atctgaaaaa attaataaac cagagcaatt aaatgaaata tgttctgcca
    10441 taataattgc caaaacttta atttggttat ttattacttt tatatatgtg atctgtattt
    10501 tgcaatttgt accagataat aaaaataagg tactatactt atcagcttat acactaacat
    10561 ttaatgaatt tttagtttgt caatggttct atcaagcaat tgaagaactt aaaataatcg
    10621 caactttatc tatcatatct aaagttacaa atgtgattct tatatttcta ttagtgaagt
    10681 cgccttcaaa ttattatttt gtttctctta taactggcgg ggcttatttt tttacaggag
    10741 tatattctat actccatatg tttagacatc atattaaatt tgtagttcct agtatcagcg
    10801 ttattattaa cgtaacgaag gatagtttta atcttttttt aacatctgca attattgcta
    10861 taaaaaataa actggatgtt atcctaatcg gcgcttttat ttcaagtgaa atggttgcca
    10921 tttatgattt tgctcaaaaa attcttaata ttttactact tccaattaca ataataagca
    10981 atgctacttt cccccggatg aaccgagaaa aaaataagat atttctaaag aaaataattc
    11041 tagtttcatt tggattaaca tttatttata taacttttag tgagttacta ctgccatata
    11101 taatgcatta tatatttgtt gtaagtcatg attcgattaa tatcactaga ttaatgatct
    11161 tgtcagcaat atttctttct ttaagtttac cattagctca gaatggtcta attgttttta
    11221 attatacgaa actgcactta ttgggtatgt tatcaacgac ggcattgtat attggcataa
    11281 tggctttagg ttataagtgc agccttttaa ctgatgttta ttattttgta tatacatctc
    11341 ttatactttt tgcgtacgaa gctttttatc gttattcatt ctgtaaatgg aagagaattt
    11401 tatgagtcaa caaattaagt attatggtta tactggtgat cttgtactac aagatacaga
    11461 tttacttgaa ctgaactatt tttcagaaat taagaagatc tgtattgatg agtcaattag
    11521 cttaattgtt aatcttgaat ttataaagat ttcattaaaa ttaaagataa gtcctgtttg
    11581 gggctaatca aaggaatgta gataaattac attatctatc accgacatta agtaataatc
    11641 acataaatga ctttgggaat gatggtgttc aactgattca taacatattg cttaacaata
    11701 actttaattc atttggtgtt ggaaaacacg gtgatataaa aataatagat aacactgcag
    11761 ataatcttat aaacatggct ttacactttg agattctgat cagtctagta gcttattatt
    11821 tgctactgat caagtatatg gccctagcga tttagacttg aaattcatta gcgaagttaa
    11881 gaaaaataat acgactaaaa atttagtagt atctgtacat tgggggacta aagatatttc
    11941 cgttccagat cgtgaaacaa gaatcatagc tagaaaaatt atcgatgcgt gtgcagattt
    12001 ggttatagga caccatcccc atattgtaca accacttgaa atctataaag agaaaatgat
    12061 tttctactca gttagtaatt ttttattttc cagacattaa atactcattc aagaataaaa
    12121 ttgtagaaaa actattaagc atcagataat aagattgttc ctgtattcga tttttcagat
    12181 actgtacgat tgggtaaaat ttatgaaatc gggaataacg atcaaaagca aatagttcgt
    12241 attattaaac caaaggaacc aattaaatcg aaaaatatac tattcatttt tccctgttta
    12301 atataaaaat gaatctatga gacttgctaa atattattct caaagacttg tggagagaat
    12361 tacatcatgt tttcattaag tgattttttg agtaacctaa aggctatatt attacctgaa
    12421 tcgttgtgtt aaaaaatatt tttgtcaagc atactggata tgaattaatt cattagaatc
    12481 ctcaaatgtt aaatgaaaag ttgcaatgga tgaaattaaa ctatcgaaaa gacattctaa
    12541 caatatgtgc cgatgttagc tgtacgagat tatatatctt ctacgatagg gaatgattat
    12601 ttggtgccac ttgtattttc aactgaggaa ccagaagatt tacattccct gattatcctg
    12661 taatcataaa ggcaaaccac gatagtgggg attatcatat aattagggat aaaaaaactg
    12721 aagattgatg aaattattat cgatgctaaa aaatagttga ataacaatca tttttgaaag
    12781 cgaaagaatg gcaatataaa aatataaaac ctaaaattat aatagagcgt ctattgatgg
    12841 actcgaatgg taaaattcca aatgatatca aatttagttg cactaatggc aatgctgaaa
    12901 ttgtttatct tgattctaat aaagaaataa aacacttgcg aaataattat ccacgcaatt
    12961 ttgaactctt agtaataaat tggccagaag aatatcaacg gaattcatat ataaaaatgc
    13021 ctgataactt ttttaaggct cgtgaattag ctgaaaggct tgcagatccc ttcccatttg
    13081 taagagctga tttctatctt attgataatt aaatttattt tggagaatta acatttcacc
    13141 cgatttcagg atttggacgt ttttaacccc aatatgatga ttataaattt ggtagtagat
    13201 taaaactacc caatgtaaat tggaacaaaa aatgaaagta atcaacacat ttataaatgg
    13261 tttgaaaata attgaacctc aggtacatat ggataataga ggtttttttc ttgaaactta
    13321 ttcagaggaa aagtattgcg aattaattgg tagagaatta cattttgtgc aagataatca
    13381 ctccagatca actaaaggag ttcttagagg gctacatttt caaagcaagc atcctcaggg
    13441 taagcttgta cgtgttactc gcggtattgt atttgatgtt gcagttgatt tgagaattaa
    13501 ctcacagacc tttggcaaat ggtttggcat cattttatct gaagacaata aacgacagtt
    13561 gtggttgccg gaaggatttg ctcatggatt tcaagtatta tcagatattg cagattttga
    13621 atataaatgc actgattatt actatccgga gtttgagcga actttgctat ggaatgatgc
    13681 agatgttaat atttcctggc ccctcgctct ttccataata tcagagaaag ataaaagagg
    13741 acattcctta tcagaaatta aatcttatat ctaaaattaa atcattagat ctaatgattc
    13801 ttcgtatcct aagtttattg caatttacaa attgcgagtt ttttatcctc aagcttttta
    13861 actgagttac catcacacca ttaattttaa atggtgtacc tgacaggagt aaacaatgtc
    13921 aaagcaacag atcggcgtcg tcggtatggc agtgatgggg cgcaaccttg cgctcaacat
    13981 cgaaagccgt ggttataccg tctctatttt caaccgttcc cgtgagaaaa cggaagaagt
    14041 gattgccgaa aatccaggca agaaactggt tccttactac acggtgaaag agtttgttga
    14101 atctctggaa acgcctcgtc gcatcctgtt aatggtgaaa gcaggtgcag gcacggatgc
    14161 tgctattgat tccctcaagc catacctcga taaaggtgac atcatcattg atggtggtaa
    14221 taccttcttc caggacacca ttcgtcgtaa ccgtgagctt tctgccgaag gctttaactt
    14281 cattggtacc ggtgtctccg gtggtgaaga aggcgcgctg aaaggtcctt ccattatgcc
    14341 tggtgggcag aaagaagcct atgaactagt tgcaccgatc ctgaccaaaa tcgccgcagt
    14401 ggctgaagac ggtgagccat gcgttaccta tatcggtgcc gatggcgcag gccattatgt
    14461 gaagatggtt cacaacggta ttgaatacgg agatatgcaa ctgattgctg aagcctattc
    14521 tctgcttaaa ggtggcctga acctcaccaa cgaagaactg gcgcagacct ttaccgagtg
    14581 gaataacggt gagctgagca gctacctgat cgacatcacc aaagacatct ttactaaaaa
    14641 agatgaagag ggtaactacc tggttgatgt gattctggat gaagcggcta acaaaggtac
    14701 cggtaaatgg accagccaga gtgcgctgga tctcggcgaa ccgctgtcgc tgattaccga
    14761 gtctgtgttt gcacgataca tctcttctct gaaagatcag cgcgttgccg catctaaagt
    14821 tctctctggt ccgcaagctc agtcagcagg cgacaaggct gagttcatcg aaaaagttcg
    14881 ccgtgcactg tatctgggca aaatcgtttc ttacgcccag ggcttctctc agctacgcgc
    14941 tgcgtctgaa gagtacaact gggatctgaa ctacggtgaa atcgcgaaga ttttccgtgc
    15001 tggctgcatc attcgtgcgc agttcctgca gaaaatcacc gatgcttatg ccgaaaatcc
    15061 gcagatcgct aacctgctgc tggctccgta cttcaagcaa attgccgatg actaccagca
    15121 ggcgctgcgt gatgtcgtcg cttatgcggt acagaacggt atcccggttc cgaccttcgc
    15181 cgctgcggtt gcctattatg acagctaccg ttctgctgtt ctgcctgcga acctgatcca
    15241 ggcacagcgt gactatttcg gtgcgcatac ttataagcgc attgataaag aaggtgtgtt
    15301 ccataccgaa tggctggatt aatctgattt aaatcaatta atcaaagcaa ggcccggaga
    15361 aaccctccgg gcttttttat tatacaaagc ggcaggttat ggcctttttt tataatttat
    15421 gattaaaaaa gcgatataat acagagccgc acagcaggat cgctgtcttg acagttcaac
    15481 cgcatcagcg ttaaaaatcc cgcagtagat gaagttgtgg tggtgtacta atgaccactc
    15541 taaatgttta accggaagaa gtcagagcta atgaaaataa caatttcagg aacaggttat
    15601 gttggtcttt caaatggtat tctgattgcg caaaaccacg aagtggttgc actggatatc
    15661 gttcaggcca aagtggacat gcttaacaag aagcagtcac cgattgttga taaggagatt
    15721 gaagagtatc tggcgtctaa agatctcaat ttccgcgcta cgacagataa gtttgacgcg
    15781 tataaaaatg ccgattacgt tattattgcc acacctaccg attatgatcc gaaaacgaat
    15841 tattttaata cctcaagcgt ggaagcggtc attcgtgatg tgacagaaat taatcccaac
    15901 gcggtaatga ttataaaatc aactatccct gtcggtttta cagagtccat taaagaacgt
    15961 tttggtgttg aaaatgtgat cttttcgcct gagtttttac gcgaagggaa agcactttat
    16021 gataacttac acccatcacg catagtgatt ggagagcagt ctgaacgcgc tgaacgtttt
    16081 gccgcattat tacaagaagg tgctattaag caagatattc caacgttgtt tactgactca
    16141 acagaagctg aggcgattaa actttttgca aacacctatc tggcgatgcg cgtggcgtac
    16201 tttaacgagc tggatagtta tgcggaaagt ttaggtctga atactcgcca gattatcgaa
    16261 ggcgtttgtc tcgatccgcg tattggcaac cattacaaca atccgtcgtt tggttatggt
    16321 ggttattgtc tgccgaaaga taccaagcag ttactggcga actaccagtc tgtgccgaat
    16381 aacctgatct cggcaattgt cgatgccaat cgcacgcgaa aagattttat tgccgattct
    16441 atccttgcac gtaaaccgaa agttgttggc gtctatcgtc tgattatgaa gagtggttcg
    16501 gacaatttcc gtgcttcctc gattcagggt attatgaagc gaatcaaggc gaaaggcgtc
    16561 cctgtaatcg tttatgagcc agctatgaaa gaggacgatt ttttccggtc gcgcgtggta
    16621 cgtgatctgg atgcgttcaa acaagaagct gatgttatta tttctaaccg tatgtctgcc
    16681 gatctgactg atgtagcaga taaggtttat acgcgcgact tgtttggcaa tgattaatta
    16741 ttttgtttca tactaagaaa aggccctaat aaattagggc cttttcttat agttttgtaa
    16801 aatcaaactt tatagaagtt acgataccat tctacaaaat tctttacccc ctctttaact
    16861 gacgtttcag gtttgaatcc tattacgtca tacagtgctt ttgtatcagc actggtttcc
    16921 agtacatcac cgggttggag aggcatcata tttttgttgg cttcaatacc cagagcctct
    16981 tctaacgcat tgatatagtc catcaactct acaggcgaac tattaccaat gttatagaca
    17041 cgatatggtg ctgaacttgt tgcaggcgag cctgtttcta cagcccactg tggatctttt
    17101 tctggaataa catcctgtaa gcgaataata gcttcagcaa tatcatcaat ataagtaaag
    17161 tcacgcttca ttttgccgaa gttgtaaaca tcaatgcttt taccttccag catggcttta
    17221 gtaaatttaa ataatgccat atccggacgt ccccatggac cataaaccgt aaagaaacgc
    17281 agccctgtgg tcggtaagcc atacaaatga gaatacgtat gggccatgag ttcatttgct
    17341 tttttagttg ctgcataaag cgaaacagga tgatctacag agtcatctgt agagaaaggc
    17401 atcttgcggt tcatgccata aacagaactg gaggaagcgt aaagtagatg ctgaatatta
    17461 ttatggcgac atccttccag tatgttcagg aatccaatca ggtttgcatc tgcatatgca
    17521 ttgggatttt caagggagta acgtacacct gcttgcgcag cgaggtttat tacgcgttcg
    17581 aaccgctcgt ctacaaacag tgccgccatt ttctcgcgat cggccaggtc aattttataa
    17641 aaactgaaat tgtcgtgctt gagtaaatca agtcgtgctt gtttgaggtt gacatcgtaa
    17701 taatcattta agttgtcaat gcctacaacc tgatgaccag ctgcaagaag ccgtttactt
    17761 acatagaaac cgataaagcc agcagctccc gtaaccagaa atttcattta taatcctcgc
    17821 tcaggctaga atatagccaa ttttcatcta gcataactga aagttaaatc ataccgttag
    17881 acaagaaaaa aagataatcg gtatcagttc taaacctggc tgttttttct ggtaacgtgc
    17941 tcattttaca atcaaagctg ttctaagctg actatacaag ccgacgtcat tatctccaac
    18001 cgtatggcag aagagcttaa ggatgtggca gataaggtct acacccgcga tctctttggc
    18061 agtgactaac atcctgttat cagggcgatt ttcgccctga ttctcttatg ttccctttgt
    18121 aataattcat tgtttttatc atttatccta tagcattcat ggcgattatc gctaaactat
    18181 ggcgacttaa aattatttcg tccgttaggg taatgatgag agtagaaaat aataatgttt
    18241 ctgggcaaaa ccatgatccg gaacagattg atttgattga tttactggtc caactatggc
    18301 gcggcaagat gactatcatc atttctgtca ttgtggctat tgccctggct atagggtatc
    18361 tggtcgttgc caaagaaaag tggacttcaa cagctatcgt tactcaacct gatgtgggac
    18421 aaatcgctgg ttataacaat gccataaatg tgatttatgg ttcggcagcg ccgaaagtgt
    18481 ctgagatcca gtcgatgtta attggtcgtt tcagcacgac attttctgca ttagcagaaa
    18541 cgctggataa tcaggaagaa cctgaaaaac tgaccattga gcctaccgtt aaaaatcagt
    18601 cattaccttt agcggtttct tatgtcggtg aaacacctga aggtgcgcag aaacagctgg
    18661 cgaagtatat ccagcaagtt gacgaccagg taaatgaaga actggaaaaa gacctgaaag
    18721 acaacatcgc gctgcgtatg aaaaacttgc aggattctct gaaaacccag gaagtggtcg
    18781 cgcaggagca gaaagatctg cgtatccgtc agattcagga agcgttgcag tatgcgaatc
    18841 aggcgcaggt gacaaagccg cagattcaac agacgcagga cgtaacccag gatactatgt
    18901 tccttttggg gagcgaagcg ctggaggcga tgattaagca cgaggcgacc cgtccgttgg
    18961 tgttctcatc aagctactat cagactcgtc aaaacctgct ggatatagac aatcttgacg
    19021 ttgataaact tgatattcat gcttaccgct atgtaatgaa accgacgtta cctattcgtc
    19081 gcgatagccc gaaaaaggca atcaccttga ttctggcagt gctgctgggc ggtatggtgg
    19141 gcgcggggat tgtgttgggg cgtaacgcac tgcgtaatta caacgcgaag taatcttttt
    19201 ggttttaaag aaaacgggca gggtggtgac accttgcccg tttttttgcc ggatgcgaca
    19261 acaacatcgc atccgcttac cccgccactc actgatgccg tttacgcagg ttctcaatta
    19321 ccgtcgttaa atccagatcc tgatcctgca acaacaccag caggtgatac atcaagtcag
    19381 atgcctcgtt ggtcagctca aagcggtcat gtaccgttgc tgccagtgcg gtttccacgc
    19441 cttcttcgcc cactttctgc gcaatgcgtt tggtgccgct ggcatacagt ttggcggtat
    19501 aggaggtttc cgggttggca gatttacgtt cggcgagcag ttgttccagt tgatacagga
    19561 acagccactg gtgagcggtg tcgccgaagc agctgctggt gcctttgtgg caggtcgggc
    19621 cgatgggatt cgccagcaac agtaacgtgt cgttgtcgca gtccggcgta atatttacta
    19681 cgttgaggaa attgcccgac gtttcgcctt tggtccacag tcgctgttta gtgcgcgaga
    19741 agaaggtgac tttgccgctt tcgatggttt tgtctaaggc ttccgggttc atgtagccca
    19801 gcattaacac ttcgccagat accgcgtgtt gcacaatcac cggcatcagt ccgtcggttt
    19861 tttcccagtc cagttcgcga cgttgttgtt ctgttaacat atcctgatct ccacgccctg
    19921 tgttgccagg tacgctttta attcgccaat attgattatt tgtttgtgga atacggaagc
    19981 tgccagcgca ccgtcaacgt cggcatcgcg gaaggcttct aggaagtgtt ccatggtgcc
    20041 cgcgccaccg gaggcaatca gcgggacgtg gcaaacttca cgcacttttt tcagctgttc
    20101 gaggtcgtaa ccgttacgca cgccgtcctg attcatcatg ttgaggacga tttctccggc
    20161 accgcgtttt tgcacttcct gcacccagtc gagtgtt
//