LOCUS       AY528413               18900 bp    DNA     linear   BCT 06-FEB-2006
DEFINITION  Escherichia coli O52 O-antigen gene cluster, partial sequence.
ACCESSION   AY528413
VERSION     AY528413.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18900)
  AUTHORS   Feng,L., Senchenkova,S.N., Yang,J., Shashkov,A.S., Tao,J., Guo,H.,
            Cheng,J., Ren,Y., Knirel,Y.A., Reeves,P.R. and Wang,L.
  TITLE     Synthesis of the heteropolysaccharide O antigen of Escherichia coli
            O52 requires an ABC transporter: structural and genetic evidence
  JOURNAL   J. Bacteriol. 186 (14), 4510-4519 (2004)
   PUBMED   15231783
REFERENCE   2  (bases 1 to 18900)
  AUTHORS   Feng,L., Senchenkova,S.N., Yang,J., Shashkov,A.S., Tao,J., Guo,H.,
            Cheng,J., Ren,Y., Knirel,Y.A., Reeves,P. and Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2004) Center for Functional Genomic Research,
            TEDA College, Nankai University, Hongda Street, Tianjin 300457,
            P.R. China
FEATURES             Location/Qualifiers
     source          1..18900
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /serotype="O52"
                     /db_xref="taxon:562"
     gene            <1..762
                     /gene="galF"
     CDS             <1..762
                     /gene="galF"
                     /note="UTP-glucose-1-phosphate uridylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="GalF"
                     /protein_id="AAS99158.1"
                     /translation="IVAAGIKEIVLVTHASKNSVENHFDTSYELEALLEQRVKRQLLA
                     EVQSICPPGVTIMNVRQAQPLGLGHSILCAHPIVGDNPFVVVLPDIVLDNASADPLRY
                     NLAAMVARFNETGRSQVLAKRMPGDLSEYSVIKTKEPLDVEGKVSRIVDFIEKPDQPQ
                     TLESDLMAVGRYVLSADIWPELAKTVPGAWGRIQLTDAIAELANKQSVDAMLMTGESY
                     DCGKKMGYMQAFVQYGLRNLKEGAKIRKSIEKLLS"
     gene            1186..2274
                     /gene="rmlB"
     CDS             1186..2274
                     /gene="rmlB"
                     /note="dTDP-glucose 4,6-dehydratase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlB"
                     /protein_id="AAS99159.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVINVDKLTYAGNLESLT
                     EIENNERYKFEHADICDSVAIANIFAHHQPDAIMHLAAESHVDRSITGPADFIETNIV
                     GTYILLEEARKYWLALSEDRKGAFRFHHISTDEVYGDLPHPDEVSSDTILPLFTEQTS
                     YSPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLIILNAIAG
                     KLLPVYGNGEQIRDWLYVEDHARALYEVVTKGVPGETYNIGGHNERKNIDVVKTICRI
                     LDELIADKPDGIENFEQLIRYVSDRPGHDLRYAIDASKIKQDLGWVPQETFETGITKT
                     IHWYLNNKEWWQRVMDGSYAGERLGLVE"
     gene            2287..3156
                     /gene="rmlA"
     CDS             2287..3156
                     /gene="rmlA"
                     /note="glucose-1-phosphate thymidylyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="RmlA"
                     /protein_id="AAS99160.1"
                     /translation="MKGIILAGGSGTRLYPITRGVSKQLLPIYDKPMIYYPLSTLMLA
                     GIQDILIITTEEDNASFQRLLGDGSNFGIRLNYAVQPSPDGLAQAFLIGEKFIGNDKV
                     CLVLGDNIFYGQSFIKILQNAVAREYGATVFGYQVKDPERFGVVEFDSEMRAVSIEEK
                     PSKPKSNYAVTGLYFYDNRVIDFAKKVKPSVRGELEITDLNDMYLKEGTLNVELLGRG
                     FAWLDTGTHESLHEASSFVQTIQNVQGLKVACLEEIALRNGWLSKEEAIKNALPMKKN
                     DYGQYIIARAKGE"
     gene            3156..4106
                     /gene="fcf1"
     CDS             3156..4106
                     /gene="fcf1"
                     /note="reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="Fcf1"
                     /protein_id="AAS99161.1"
                     /translation="MDARKNGVLITGGAGFIGKALITEMVERQIPLVSFDISDKPDSL
                     PELSEYFNWYKFSYLESSQRIKELHEIVSRHNIKTVIHLATTMFPHESKKNIDKDCLE
                     NVYANVCFFKNLYENGCEKIIFASSGGTVYGKSDTPFSEDDALLPEISYGLSKVMTET
                     YLRFIAKELNGKSISLRISNPYGEGQRIDGKQGVIPIFLNKISNDIPIDIIGSIESKR
                     DYIYISDLVQAFMCSLEYEGHEDIFNIGSGESITLKKLIETIEFKLNKKAVIGFQDPI
                     HTNANGIILDIKRAMAELGWRPTVVLDDGIDKLIKSIRCK"
     gene            4109..5242
                     /gene="fcf2"
     CDS             4109..5242
                     /gene="fcf2"
                     /note="mutase"
                     /codon_start=1
                     /transl_table=11
                     /product="Fcf2"
                     /protein_id="AAS99162.1"
                     /translation="MNKVLIIGSGFSGATIARLLAEENIKVKIIDDRKHIGGNCYDER
                     DEKTGINVHVYGPHIFHTDNEDVWNFVNKYGTFQPYTTRLKANAKGQIYSLPVNLHTI
                     NQYYKTALSPTEARKLIASKGDQTINDPQSFEEQALKFVGEDLYKTFFYGYPKKQWGM
                     EPKEIPASVLKRLPVRFNYDDNYFFHKFQGIPRDGYTPLFQNLLNHPNIEFELGKKVN
                     RATVEELITSEQYGHVFFSGAIDHFYDYEFGMLQYRTLDFEKFYSEDDDYQGCVVMSY
                     CDEDVPYTRVTEHKYFTPWEEHKGSVLYKEFSRSCDKEDIPYYPVRLVSGNSIWNKYE
                     QKAKEETNITFIGRLATYRYLDMDVCIKEAIECAQLYIKNNKE"
     gene            5239..6093
                     /gene="wbrV"
     CDS             5239..6093
                     /gene="wbrV"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="WbrV"
                     /protein_id="AAS99163.1"
                     /translation="MIYTVVMVSYNRTSKLKESIVQLLATNINEIIIVDNHSGKETRA
                     ILEEASLQDERVKIINLDENRGASFGFSIGLNYVEEKYEQSVTTFLDDDAYFDQVFLD
                     NLKIECKHYEYRFPFITPKVINKKGMRLTMNRPMTCIPRSLFKVVKYLKNRRQFGEKN
                     ELVEAASFIGLTIVNTADDKKSLLIPIDYFIYYDDLTFTHRLAKKNGELGIYLNDLVV
                     MHDIEGGVRKYDAFRLSYLLSNSIKFSKEVGDTLYIYSMFIHCYHFLNCLKNLKLTVF
                     VRALLRKR"
     gene            6095..6868
                     /gene="wzm"
     CDS             6095..6868
                     /gene="wzm"
                     /note="permease"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzm"
                     /protein_id="AAS99164.1"
                     /translation="MSIMSLKTLELVWVKAKLNLKSEASINYLSYAWWIIEPVLQMAI
                     YYLVFAYLLKQGGHDYVPFLLTGLIPWIWFGRSVSHAQGSIIQGKYLMNQVHISKIFF
                     PLTFILQDALKQILVFILLFIFLVLYGYDYTLGLLWIIPVIFVQLLLIVAFSLIVSII
                     VPFVRDFSFVIETGLQIMMFCSGIFFNYKSIPAMESKIFFINPMAVILSSYRDVLMYH
                     NAPNIKLLAYVVLLSLIMISISLYAFKRLEFIFPRVVQK"
     gene            6865..7839
                     /gene="wzt"
     CDS             6865..7839
                     /gene="wzt"
                     /note="ATP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzt"
                     /protein_id="AAS99165.1"
                     /translation="MKNEKIIELKNVGLVYREKKTLFTYDEYEALTNITFDVYRGETL
                     GIIGRNGAGKSTLLRVLAGIIKPDSGQITIHSNSISLMALQAGFDPNLSGRQNTIFSG
                     MVLGHRLSYIKSIIEDIKVYSELNEFFEKPIKNYSSGMLARLGFSIAMYTTPEVLLID
                     EVLGVGDVTFAEKAQKSIREKIKSDTTVVIVSHDEHQLKLLSDRLVCIENGVVLDEGP
                     RDSVYNKYNLIMKLTSYGLKLLEYKNTETVAFKVGDINPTAEYSDVNFNIDVDVVSVS
                     FKTTTSDWERVSIKDNSFWLRLNHNKIYKIKFKDTKDHDGVFELSVGY"
     gene            7913..8746
                     /gene="dmhB"
     CDS             7913..8746
                     /gene="dmhB"
                     /note="6-deoxy-D-mannoheptose pathway protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DmhB"
                     /protein_id="AAS99166.1"
                     /translation="MRKVFILGSTGYVGNHLKSFLSDAFSLVTVGRKNSDIHFDLETG
                     EFNDLLDQVNNDDTIIFLSAVSAPDQCEKNYDVAHKINVKNTITLISELLKKNARVIF
                     SSSDVVFGGTSDVCTEMSERKPFGKYGQMKCEVEEHFSNNPGFFVIRFSYILGKGDKF
                     SEMVKEHSLNSKLLDVFDGFERSVVSINDVLLGIKNIILNWSQIDTRIVNFSGPDLVS
                     RQQIVLALAQEKFPELQYQFTDAPESFWLGRPKKINTKSRFLESILDRSCESYLNVIK
                     G"
     gene            8753..9781
                     /gene="dmhA"
     CDS             8753..9781
                     /gene="dmhA"
                     /note="6-deoxy-D-mannoheptose pathway protein"
                     /codon_start=1
                     /transl_table=11
                     /product="DmhA"
                     /protein_id="AAS99167.1"
                     /translation="MNNVLITGFTGQVGSQLADYILENTTDTVIGMMRWQEPMDNIYH
                     LTDRINKKDRVFIQYADLNDYTSMYNLIEAKRPKFIFHLAAQSFPRTSFDIPIETLQT
                     NIIGTANLLECIKKLKQQDGYDPVVHVCSSSEVYGRAKVGEALNEDTQFHGASPYSIS
                     KIGTDYLGRFYGEAYGLRTFITRMGTHTGPRRSDVFFESTVAKQIALIEAGHQEPKLK
                     VGNLASVRTFQDARDAVRAYYLLALESEKGNVPFGEAFNIAGEEAFKLPEVIDLLLSF
                     STRDDIEVVTDTDRLRPIDADYQMFDNTKIRNFIDWKPEIKATDMFRDLLQHWRKEIA
                     SGRIPLNR"
     gene            9798..10826
                     /gene="hddA"
     CDS             9798..10826
                     /gene="hddA"
                     /note="D-heptose 7-phosphate kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="HddA"
                     /protein_id="AAS99168.1"
                     /translation="MKVRSKAPLRLGIAGGGTDVSPYSDTFGGCVLNATINMYAYAYI
                     DDELEGSKVIFEATDLNIREEIDLTNGVTIEGKLKLHRAVYLRVMNDYFDGELKPVRI
                     ITHSDAPAGSGLGSSSTVVVSMLEGLRQMYSLPLGEYDLAQLAFKIERVDCGLSGGKQ
                     DQYAATFGGFNFMEFYEGNRVIVNPLRIRRYIINELESSLILYFTGASRDSAKIIDDQ
                     IRSLESDKESKLMAMHKVKESAYQIKEHLLKSDIDAMAATFLDAWESKKNTSSSISNP
                     MIEKIEKEVFSIGVKSMKVSGAGGGGFMMLFVEPERKQLIERKLQEFGGEVYKFQFVE
                     DGAYSWTM"
     gene            10814..11404
                     /gene="gmhA"
     CDS             10814..11404
                     /gene="gmhA"
                     /note="glyceromannoheptose-7-P isomerase"
                     /codon_start=1
                     /transl_table=11
                     /product="GmhA"
                     /protein_id="AAS99169.1"
                     /translation="MDNVNYIKAYLDDSIAVKKLLQESDSVLSQISLVADLIINAYKN
                     GNKVILAGNGGSAADSQHIAAEFVSRFFFDRPGLPAIAITTDTSMLTAIGNDYGFDKL
                     FARQLQAQSKPGDVFIGISTSGNSVNIINAMELAKELGVTSVALCGEAGKLKDLVDYS
                     INVPSKITPYIQECHICIGHMICAIVERAIFKPEDK"
     gene            11407..12084
                     /gene="hddC"
     CDS             11407..12084
                     /gene="hddC"
                     /note="D-heptose 1-phosphate guanosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="HddC"
                     /protein_id="AAS99170.1"
                     /translation="MYDVVILAGGLGTRLKSVSGELPKPMVDISGQPFLYRLMTYLEK
                     QGATRIILSLSYKADYIIDRVVHDNPVGCEVDFVVEKEPLGTGGAIKYASSKVRTDKF
                     IVLNGDTYCELNYSDFIEASKGTDLLISGVEVNDVARYGSLDLDEKSNVNAMVEKGRT
                     GPGIINSGIYIVSKEIMSKFAGNKFSFESDFLPKFKGEFKAYVNSSYFIDIGIPEDYF
                     IACERFK"
     gene            12081..12611
                     /gene="gmhB"
     CDS             12081..12611
                     /gene="gmhB"
                     /note="D-heptose 1,7-biphosphate phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="GmhB"
                     /protein_id="AAS99171.1"
                     /translation="MKVAFLDRDGVINKEVNYLYKIEDFEFTKNCISGMKRFIAHGYK
                     IIIVTNQAGIAKGYYTLSDYDKLTKWYRGILKSQGIDILDIYYCPHHPDGIGPEYRCD
                     CPCRKPNTGMFESAARDYSIDLKQSFIVGDKLGDVEAGLKFGLGRVFLVETGHQIPAV
                     GYATYPVYSDLLSIPL"
     gene            12608..13936
                     /gene="wbrW"
     CDS             12608..13936
                     /gene="wbrW"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="WbrW"
                     /protein_id="AAS99172.1"
                     /translation="MKNTITRFLKKAFVKFRYTRLARKLWKLFALMVNAHYPRRLLIK
                     ALNVNAEQNANEFTVFPKILKSSSDKNALVIMPFYGNDAVGKNIDTKIATLKSLGFTI
                     HAIVFNNSPWDSNSVDWDYTYNIKCRNGKFGTLRHDVNQQIIPDGNKIDDWLDDEICQ
                     FVAALSAMNNYQIAIVNYVFLSKLCLYLKPNTVSVIDTHDVFAKRNTRMAKIGISQDK
                     FYFSTSKKEETIGLSRANYIFAIQEAEGRYFRENVSSQVIVQPPILDVNFIDYVPTSN
                     KKIVVGFMASGHYPNVVAINNFIDSLSKLDHNVRLDISGTICGALEGRQYPGFVNILG
                     FCESLDKFYHSCDVIINPDELLSGLKVKCLEALSYGVPLVSTKAAMEGIESTEEYHQI
                     ESAQKCAEFITSLKKDELINMATHSRNVFANFNQRYNFQSTLRKVLKDNG"
     gene            13929..16088
                     /gene="wbrX"
     CDS             13929..16088
                     /gene="wbrX"
                     /note="bifunctional enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="WbrX"
                     /protein_id="AAS99173.1"
                     /translation="MGDDIFKISVILPVYGGEVYLEQCLDSVLSQTYKNLEIIIVNDG
                     SPDACPQIIDRYASSDTRIIAIHKKNAGYGAAINSGLDVASGDFISIIETDDWVQLDM
                     FERLIDAYNKIPNPVIKASFNRISNEVVINTQSLAHLCTFDNDNLAEIVPENSVELFL
                     LESSIWTGLYRRDFLEENHIRFYESPGASYQDMPFKFITYASVEKITLLNVPVYNYRV
                     MNVGSSSASADKALISFNNYDIIKKHLLSVGTFQKYLNHFYFHHLFDLVFHYSRLRGD
                     GLKSYQEAAIAVFEQAKEEGFQPVTSNVSFSSDTNDYYYNHVLPIYNELMSNRIIKTV
                     QTRNRIKKKVVSKLRFITNKLIIEPIINAVSSKMDSSSSLLSKHFREELDSSFLKMSK
                     ELTDKVDVISGQNKNGSVLIKVAPTNQFYYYMKVNSSRISKLREEFKRGLDEFSLQNE
                     RKLFGFYELLPYFEHQGIELELPLSLTLFTDEDRVILSNIDSILRHEKELIQHLDLSE
                     LPVTLATNYFKAGLKYLPGRFTEEFKGSVAIDCGAWVGDTAIMFASFGFKEVLALEPV
                     ADNYNCMVRNLERNHQYLNDTIKPLNVAVSNVSGELSMMKVGDDGVGSCVVEDEQSDI
                     KVQSVTIDSLTFEDRVGLIKFDIEGYEINALNGAIETIKKHKPVLLISVYHLWLQPEQ
                     IFECKKFVENLNMGYQFKFVHLQPERDLVYEYMLVCW"
     CDS             16244..17389
                     /note="Orf16"
                     /codon_start=1
                     /transl_table=11
                     /product="nonfunctional galactosyl transferase"
                     /protein_id="AAS99174.1"
                     /translation="MKIKICYFVNSAWYFELHWLDRALSVLEAGYDVYIFANYSDKSI
                     LDRFTSLGFKCIDSKIKEQNINPVVFFCDITRSFRTLNKINPDIVHSRTIKPGVISCL
                     WARIRNKKMVYSFVGLGRVFESNKVIYQMVKFLIANMYRRFFLNIDCCILFEHKKDQQ
                     KIIELLDIPKNKTEVIDGAGINIDYFCYSTPPNNTKVKVFFASRMLWSKGLRTLIDAS
                     RILKLQGIEFEILVAGILVDNDRDAISITQIEEWHNSGDIIWLGKRSDIKELIESVDI
                     VALPSVYSEGIPRILLEAGAIGRPVISFDTGGCGSLILDGYNGFLVPKGNVNLFSQKL
                     GILISDPLERTKMGQNARKRVEEKYSSTVVIRKTVQIYNKLTMQEVL"
     gene            17561..>18900
                     /gene="gnd"
     CDS             17561..>18900
                     /gene="gnd"
                     /note="6-phosphogluconate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="Gnd"
                     /protein_id="AAS99175.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVVA
                     ENPGKKLVPHYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELATT
                     FTEWNEGELSSYLIDITKDIFTKKDEDGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLTGPQAKLAGDKAEFVEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENASIANLLLAPY
                     FKNIADEYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRD"
ORIGIN      
        1 attgtggctg cagggatcaa agaaatcgtt ctggtcacac acgcatcgaa aaactcggtg
       61 gaaaaccact tcgatacctc gtatgaactg gaagcactgc ttgagcagcg cgtgaagcgt
      121 cagctgctgg ctgaagttca atctatctgt cctcctggcg tgaccatcat gaacgttcgc
      181 caggcgcagc cgttgggcct gggacactct atcctgtgcg cacatccgat tgtcggcgat
      241 aacccgtttg tggttgtgtt gccggatatc gtgctggaca acgcaagcgc cgacccgctg
      301 cgctacaacc ttgccgccat ggtagcgcgt ttcaacgaaa ccgggcgtag ccaggtgctg
      361 gcgaaacgta tgccgggcga cctgtctgaa tactccgtca tcaaaacgaa agagccgctg
      421 gatgtcgaag gtaaagttag ccgtatcgtt gattttatcg aaaaacctga ccagccgcag
      481 acgctggaat ccgatctgat ggccgtaggc cgctatgtac tttccgctga tatctggcct
      541 gaactggcga agaccgtgcc gggggcgtgg ggccgaattc aactgacgga tgcgatcgcc
      601 gaactggcga ataagcagtc tgttgacgcg atgctgatga cgggtgagag ctacgactgc
      661 gggaagaaga tggggtatat gcaggcgttt gtgcagtatg ggttgcgcaa cctgaaggaa
      721 ggggctaaga tcaggaaaag tattgaaaag ttgttatctt aagtcgtttc tcagtaaacg
      781 ataaagcaaa tttaagaacg gcgttttaga acggcagatg ggcataagta tgtagggtaa
      841 cctactacta gcttcactgc ctttttattt cataaaacaa agtaaaaaat aacaataggt
      901 tagaaatgta ggcgttgcat atcgtttata agatttttcc ttgagttcaa atgcatttaa
      961 gacgaaaata gttgccgaaa ttttttgggt ttgcaggtgg gagtcgttgc ggatttttgc
     1021 cttgacataa atgattttta tcattgaagg tgcagtgcgc tggtagctgg agagccaggg
     1081 gcggtagcgt gtctaatcat aagtgtcttt tataatattc agattgttct taacaaacat
     1141 tcatattatc aagccataag ttataagtca tagcggaaat tcaaagtgaa aatactggtt
     1201 acaggtggtg caggttttat tgggtctgca gttgttcgtc atataattaa taatacgcaa
     1261 gactctgtca tcaatgttga taaacttacc tatgcaggta atttggaatc tctgacagag
     1321 attgagaata acgagcggta taaatttgag catgcggata tttgcgacag cgttgcaata
     1381 gccaatattt ttgcacatca ccaaccagat gcaataatgc atttggcagc cgaaagccac
     1441 gttgatcgtt caatcacagg ccctgcagac tttattgaaa ccaatattgt tggaacatat
     1501 atcttactag aagaagctcg taagtattgg ctagcactta gtgaagatcg caaaggtgca
     1561 tttcgcttcc accatatttc tacggatgag gtttatggtg accttcctca tccggatgaa
     1621 gtatcgtcag atacaatatt gccattgttt acagaacaaa cttcatattc ccctagcagt
     1681 ccatattccg cctctaaggc atccagtgat cacttagttc gtgcatggcg gcgtacatat
     1741 ggattaccca ccatagtgac aaattgttct aataattatg ggccgtacca tttccctgaa
     1801 aaactcattc cgttaattat tctgaatgca attgcgggta aacttttacc tgtttatggg
     1861 aacggtgagc aaattcgaga ttggttatat gttgaagatc atgcccgggc actttatgaa
     1921 gtcgtcacaa agggtgtgcc gggagaaaca tataatattg gtggtcataa cgaacgtaaa
     1981 aatatcgatg tagtgaaaac tatttgtcgc attctcgatg aattgattgc agataaacca
     2041 gatggcattg aaaattttga acagttgatt cggtatgtta gcgatcgtcc agggcatgac
     2101 cttagatatg ccattgacgc cagtaaaatt aaacaagatt taggttgggt gccgcaagaa
     2161 acgtttgaaa cgggtatcac taaaaccatt cactggtatt taaataataa agaatggtgg
     2221 cagcgtgtga tggatggttc gtacgctggt gaacgcttag ggctcgtaga gtagtaagga
     2281 taaaagatga aaggtattat tttagcaggc ggctctggca ctagattgta tccaataact
     2341 cgtggtgtat caaaacaact attaccaatc tatgataaac caatgattta ttacccgctt
     2401 tccacactta tgctagcggg tattcaagat atattaataa taaccactga agaagataat
     2461 gcgagtttcc agcggttact cggtgatggc agtaattttg gtattcggct taattatgcc
     2521 gtgcaaccca gccctgatgg attagcgcag gcattcctca ttggtgagaa atttatagga
     2581 aacgataaag tttgtttggt gctgggtgat aatatttttt atggccaatc atttatcaaa
     2641 atcctgcaga atgctgttgc aagagaatac ggtgcaacag tatttggtta tcaagtgaaa
     2701 gaccctgaac gcttcggtgt agttgaattt gatagcgaga tgcgggctgt atctattgaa
     2761 gaaaaaccgt caaaaccaaa atcaaattat gcagtcactg gactttactt ctatgataat
     2821 cgcgttatcg atttcgctaa aaaagttaaa ccttcagtga gaggggagct ggagattact
     2881 gatcttaatg acatgtatct caaagaaggt actcttaacg tagagctact ggggcgtggt
     2941 tttgcttggt tggatacagg gacccacgaa agtttgcatg aagcgtcatc cttcgtgcaa
     3001 accatccaga atgttcaggg cctcaaggtt gcatgtcttg aagagattgc attaagaaat
     3061 ggttggttaa gcaaagaaga agcaataaaa aatgcactac ctatgaagaa aaatgattat
     3121 ggtcaataca ttatagcacg tgcaaaaggt gaatgatgga tgctagaaaa aatggagtcc
     3181 tgattacagg cggtgctggg tttataggta aagcattgat caccgaaatg gtcgaaaggc
     3241 agatcccact agtgtcgttc gatatttcgg ataaaccaga ctcgttgcct gagctaagtg
     3301 aatattttaa ctggtataaa tttagctacc tcgaatcttc tcagcgtata aaagaactgc
     3361 atgagatagt tagccgccac aatattaaga cagttattca tttggcaaca actatgtttc
     3421 cacatgaatc gaaaaaaaat atcgataaag attgtctgga aaatgtttat gcgaatgtct
     3481 gttttttcaa aaacctatat gaaaatggtt gtgagaaaat tatatttgca tcatcgggtg
     3541 gcactgttta cggaaaatcc gatacaccat tttctgaaga tgatgcactt ttaccagaga
     3601 tcagttatgg cttaagcaaa gttatgactg agacatactt acgatttatt gctaaagaac
     3661 tcaatggtaa atccatatca ttgcggatct caaatcctta tggagaaggg cagagaatag
     3721 atggtaagca aggtgtaata ccaatatttt taaataaaat ctcaaatgat attccaattg
     3781 atattattgg ttcaattgag agtaaaagag attatattta tataagtgat cttgtacaag
     3841 ccttcatgtg ttcattagaa tatgaaggac atgaagatat ttttaacata ggttctggag
     3901 aatctattac gttaaaaaaa cttattgaaa ctatcgaatt taaattgaat aaaaaggcag
     3961 taatcggttt tcaagatcct atccatacca atgctaacgg aattatttta gatattaagc
     4021 gagctatggc tgagttagga tggcgtccga cggttgtact cgatgatggc attgataaat
     4081 taataaaatc aattaggtgt aagtaattat gaataaggtc cttatcattg gtagtggatt
     4141 tagcggtgca acaatagcaa gactgttggc tgaagagaat attaaagtaa agataataga
     4201 cgacagaaag catattggtg gtaactgcta tgatgagcgg gatgagaaaa caggcattaa
     4261 tgtccacgtt tatggaccgc atattttcca tacggataat gaagatgtat ggaattttgt
     4321 gaataaatat gggacattcc agccatatac aacgaggctt aaagcgaatg caaaaggcca
     4381 gatttattcg ttacctgtaa atcttcatac aattaatcaa tactataaaa cagcattgtc
     4441 tcctactgaa gccaggaaac tgattgcgag caaaggtgat cagacaatta atgatcctca
     4501 gtcttttgaa gaacaagctt taaaatttgt tggtgaagat ttatacaaaa cattctttta
     4561 tggctatcct aaaaaacagt ggggtatgga gccaaaggaa ataccagcat ctgtattaaa
     4621 gcgtctccca gtacgtttta actatgatga taactatttt ttccataaat tccagggcat
     4681 acctcgtgat ggctacacac cattatttca aaatttactg aaccacccaa atatagagtt
     4741 tgaattagga aagaaagtaa atagagcaac tgttgaagaa ttaatcacct ccgagcaata
     4801 cggacatgta tttttctctg gagcgattga tcatttctac gactatgaat ttggcatgtt
     4861 gcaatatcgt acgctggatt ttgaaaagtt ttacagcgaa gacgatgatt atcagggttg
     4921 tgttgtaatg tcttattgtg atgaagatgt tccttatacc cgcgtaacgg aacataaata
     4981 tttcacgcca tgggaagagc ataaaggaag cgtgttatac aaagagttta gtcgtagttg
     5041 cgataaagaa gatattccat attatccagt tagacttgtc tctggaaata gcatatggaa
     5101 caaatatgaa caaaaggcaa aagaagagac taatataaca ttcatcgggc gtttggctac
     5161 atatcgctat ctcgatatgg atgtctgtat taaagaagct attgaatgtg ctcaattgta
     5221 tataaagaat aataaagaat gatatatacg gtagtcatgg tctcgtataa tcggacgagc
     5281 aagttaaaag aatcgatagt acagctttta gcaacaaata ttaatgaaat tattattgtt
     5341 gacaatcatt caggtaaaga aacaagagcc atattagagg aagcctcact tcaggatgaa
     5401 cgtgttaaaa tcataaatct tgatgagaat agaggagcat catttggttt cagcattggg
     5461 ttgaactacg ttgaagaaaa atatgagcag tctgtgacga ctttcctaga tgatgatgcg
     5521 tattttgatc aagtattcct tgataactta aaaatcgaat gtaagcacta tgaatatcga
     5581 tttcctttta taacccccaa ggttatcaat aaaaaaggaa tgcgtttaac gatgaatcgg
     5641 ccaatgacct gcattcccag gtccttgttc aaagtagtaa aatatttaaa aaatagaaga
     5701 cagtttgggg agaaaaatga gcttgtggaa gcagcaagtt ttatagggtt aacgattgtt
     5761 aacactgctg atgataaaaa atcattactt atcccgattg attattttat ttattatgat
     5821 gatctcacct tcactcatcg attagctaaa aaaaatggtg aactaggtat ttatcttaat
     5881 gatctagttg tcatgcatga tattgagggg ggcgtgagga aatatgatgc ctttaggttg
     5941 tcatatttac tatcaaacag tattaaattt agcaaagagg ttggtgatac actatatatt
     6001 tattctatgt ttattcactg ctatcatttt ttaaattgcc tgaagaattt aaaactgaca
     6061 gtctttgtta gagctctatt gagaaaaagg taacatgagt atcatgtcgt taaaaaccct
     6121 tgaattggtt tgggttaaag caaagcttaa tctaaaatca gaagcatcaa taaactattt
     6181 aagttatgct tggtggatta tcgaaccagt ccttcaaatg gcaatttact atttggtttt
     6241 tgcatatctt cttaagcaag gtggtcatga ttacgtccca ttcctgttaa ctggactgat
     6301 cccctggata tggtttggtc gcagcgttag tcatgcgcaa gggagtatca ttcaaggaaa
     6361 gtacctaatg aatcaggtac atatttctaa gatattcttc cctttgacat ttatattgca
     6421 ggatgcgtta aagcagatac ttgtatttat tctgctattt atttttttag tcttgtacgg
     6481 ctatgattat actcttggct tgctttggat tattccagtc atttttgttc agctattatt
     6541 aatagttgca ttttctttga tagtgtcaat cattgttccc tttgtcagag atttttcatt
     6601 tgtaattgaa accggccttc aaattatgat gttttgctca ggtatatttt tcaattacaa
     6661 aagtataccg gcgatggaat cgaagatttt cttcattaac ccgatggcag taattcttag
     6721 ttcgtaccgt gatgtattga tgtatcataa tgcaccaaat attaagctgc tcgcatatgt
     6781 agttctgctt tctttaatta tgatttctat ttcgttgtat gcatttaaga gattagaatt
     6841 catcttccca cgagttgttc agaaatgaag aatgaaaaga ttattgagct aaaaaacgta
     6901 ggtttagttt atagagaaaa gaaaacactc tttacttacg atgaatatga agctttgaca
     6961 aacattacat tcgatgttta tcgtggcgaa actcttggaa taattgggcg taatggagca
     7021 gggaaatcta cattactacg agttctggcg ggtattatta agcctgattc tgggcaaata
     7081 actattcatt caaacagtat ttctctaatg gcccttcagg caggatttga tcccaactta
     7141 tcaggtcgtc agaatactat ctttagtgga atggtcctcg gtcatagatt gtcttatatc
     7201 aaatcaatta ttgaagacat caaagtatat tcagagctta atgagttctt cgaaaaacca
     7261 attaaaaatt attcatcagg tatgctagca cgtttgggtt tctcaattgc catgtatact
     7321 acccctgaag ttctgttaat tgatgaagta ctgggtgtcg gtgacgtgac ttttgcagag
     7381 aaagcacaaa aaagcattcg tgaaaaaata aagtcagaca caacagtcgt catcgtttcg
     7441 catgacgaac accagttgaa gctcctttcc gatcgacttg tttgcattga aaacggtgtt
     7501 gttctggatg aaggtccaag agacagtgta tacaataaat ataatttgat tatgaaactg
     7561 acaagttatg ggcttaagct cctggaatac aaaaatactg aaacagtagc ttttaaggtt
     7621 ggagatataa atccaacagc tgaatattca gatgttaatt ttaatattga tgttgatgtg
     7681 gtctccgtca gttttaaaac cacaacaagt gattgggaaa gagtatccat taaagacaac
     7741 agtttctggc ttcgccttaa tcataataaa atttataaaa ttaaatttaa agataccaaa
     7801 gatcatgacg gtgtatttga gctatccgtc ggttattaaa atggcagata aaattgtctt
     7861 catagcattt tatgtgcata catcttcact tcgtataatt tggtaactga gtatgagaaa
     7921 agtattcatt ctagggtcta ctggttacgt tggtaatcat cttaaatcat ttcttagtga
     7981 tgctttttcg ctggtaacag ttggaagaaa aaattcagat attcattttg atctggaaac
     8041 tggtgaattt aatgatttac tggatcaagt aaacaatgat gacaccatca tttttctttc
     8101 agcagtctct gcgcctgatc aatgtgagaa aaactatgac gttgcgcata agattaatgt
     8161 gaaaaataca attactttga tatctgaatt acttaaaaaa aatgcgcgag tgattttctc
     8221 atcaagtgat gttgtatttg gtggtacatc tgatgtgtgc actgaaatgt cagaacgaaa
     8281 accatttggc aaatatggtc aaatgaaatg tgaagttgaa gaacattttt caaataaccc
     8341 tgggttcttc gtaatacgat tttcgtacat tttagggaaa ggtgataaat tctctgaaat
     8401 ggtaaaagag cacagtttga atagtaaatt attagatgta tttgatggtt ttgagcgcag
     8461 tgttgtttca attaatgatg tattgttagg catcaaaaat attatattga attggagcca
     8521 aattgatact cgcatcgtta atttctccgg cccggatctt gtcagtcgac aacagattgt
     8581 tttggcgcta gcgcaggaaa aatttccaga actgcagtat caatttacag atgcgccaga
     8641 atcattttgg ctgggtaggc caaaaaaaat taataccaaa agtcgttttc tcgaatctat
     8701 tcttgataga tcatgtgaat catatttaaa cgttattaag gggtaagcat atatgaataa
     8761 tgtattaatt acaggattca ctggacaagt tggttctcaa ttagcagatt atattttaga
     8821 gaatacaacc gacacagtaa ttggaatgat gcgttggcaa gagccaatgg ataatatcta
     8881 tcatttaaca gaccggatta ataaaaagga tagagtattc atccaatacg cagaccttaa
     8941 tgactatact tccatgtata acttaattga agcgaagcgt ccaaaattca ttttccacct
     9001 tgctgcgcag tcatttcccc gcacctcatt cgatattccg atcgagacct tgcagaccaa
     9061 tattattggt actgccaatc tgttggaatg cattaaaaaa ctaaaacaac aagatggtta
     9121 tgatcctgtt gttcatgttt gttcttctag tgaagtttat ggtagagcaa aagtaggtga
     9181 agctttaaac gaagatacgc agttccatgg cgctagccct tacagcatta gtaaaattgg
     9241 taccgattat ttagggcgtt tttatggcga ggcatatggg ttgcgtacat ttatcactcg
     9301 catgggcaca catacaggcc cacgccgtag tgatgtattt ttcgaaagta ctgttgccaa
     9361 gcagattgcc ttgatcgaag ctggacatca ggaaccaaaa ttaaaagttg gcaatttagc
     9421 aagcgtacgt actttccaag atgctagaga cgctgtgcgt gcatactatt tattagctct
     9481 ggagagcgaa aaagggaatg ttcctttcgg cgaagcattt aatattgcag gtgaagaagc
     9541 attcaaactt cctgaggtta tagacctttt actgagcttt agcactcgtg acgatattga
     9601 agttgttaca gatacagatc gcctgcgtcc tattgatgcc gattaccaaa tgtttgataa
     9661 tactaaaatc aggaatttca ttgactggaa accggaaata aaagcgacag atatgtttcg
     9721 tgatttactc cagcactgga gaaaagaaat cgcatctggc cgcattcctc tgaatcgtta
     9781 atagggattc ttttgttatg aaagttagaa gcaaagcgcc tctacgttta ggcattgcag
     9841 gaggtgggac agatgtttca ccttatagcg atacattcgg tgggtgtgta ctgaatgcga
     9901 ccatcaatat gtatgcgtat gcttacattg atgatgagct tgaaggtagt aaagttattt
     9961 ttgaggcaac cgaccttaat atcagagaag agattgatct taccaatggt gtaacgattg
    10021 aggggaagct aaaactgcat cgagcagttt accttcgagt catgaatgat tattttgacg
    10081 gcgaattaaa accggttcgt atcattactc attctgacgc tcctgcaggt agcggtttgg
    10141 ggtcatcatc gacggttgtt gtttcaatgc ttgaaggact acggcaaatg tattctctgc
    10201 ctcttggaga atatgatctg gcccagttag cattcaagat tgagcgagta gactgtggtt
    10261 tatcaggtgg taaacaagat cagtatgctg caacatttgg tggttttaat ttcatggagt
    10321 tttatgaagg taatcgcgtt attgttaacc cacttagaat tcgtagatat ataataaatg
    10381 agttagagtc atccctgatt ctttatttta caggggcttc gagagactct gcgaaaatta
    10441 ttgatgacca gattagatct ttagagagtg acaaagagtc taaactgatg gctatgcata
    10501 aagttaaaga atcagcatat cagattaaag aacacttact caaatctgat atcgatgcta
    10561 tggccgcgac attcctggat gcatgggaaa gtaagaaaaa cacctcatcg tcaatcagta
    10621 atccgatgat tgagaaaatc gagaaggaag tgtttagtat cggtgttaag tcaatgaaag
    10681 tttcaggtgc cggtggcggt ggttttatga tgctattcgt tgaaccggag cgaaaacagt
    10741 tgatcgaacg taaactacaa gagtttggtg gcgaagtcta taaattccaa tttgtcgagg
    10801 atggagcata ttcatggaca atgtaaatta tattaaagca tatcttgatg acagcattgc
    10861 agtaaaaaaa ttgcttcagg aatctgacag tgtattgagc caaatctctt tagttgcaga
    10921 tttgattatc aatgcatata aaaacgggaa taaagtaatt cttgccggga atggtggtag
    10981 tgctgctgat tctcagcata tcgcggctga gttcgtcagt cgcttctttt tcgatagacc
    11041 aggattacca gccattgcta tcaccactga tacctcgatg ctaacggcta tcggcaatga
    11101 ctacggattt gataaactat ttgcaagaca actgcaagct caaagcaagc caggtgatgt
    11161 tttcattggc atcagtactt caggtaactc cgttaatatc attaacgcga tggaactggc
    11221 aaaagaactg ggtgtgacaa gcgtggcgct atgtggtgaa gcaggtaagc ttaaagattt
    11281 ggtagactat tcaattaatg taccttctaa aattacacca tacattcaag aatgccatat
    11341 ttgcattggt catatgatct gcgcaattgt tgaacgtgcc attttcaaac cagaagataa
    11401 ataattatgt atgatgtagt tattttggca ggagggctag gtactcgtct gaagagtgtt
    11461 agtggcgagc ttcctaagcc aatggtagat atttcagggc aaccatttct ttatcgtcta
    11521 atgacgtatc ttgaaaaaca aggagctacc agaattatac tatcattatc ctacaaagct
    11581 gactatatca tcgacagggt tgtccatgac aaccctgttg gttgtgaggt tgactttgtt
    11641 gtcgaaaaag aacctctagg aactggtggc gcaattaaat atgccagttc taaagtcaga
    11701 acggataaat tcattgttct taatggtgat acgtactgcg agcttaatta tagtgacttc
    11761 atagaagctt cgaagggaac agatcttcta atatctggtg tcgaagttaa tgatgtcgct
    11821 cgttatggta gtttagattt agatgagaaa tctaatgtta atgctatggt agaaaaggga
    11881 agaactggcc ctggaattat taacagtgga atttatattg tctcaaagga aattatgagc
    11941 aagtttgctg ggaataaatt ttcttttgaa tctgattttt tgcctaaatt caaaggagag
    12001 tttaaggcct acgttaattc ctcatatttt atcgatatag gaattcctga agattatttc
    12061 attgcatgtg agagatttaa atgaaagtgg catttcttga tcgcgatggt gtaattaata
    12121 aggaagtcaa ttatctatat aaaattgaag attttgaatt taccaaaaac tgtatcagtg
    12181 gcatgaaaag atttattgct catggttata aaataatcat tgtgacaaat caggccggaa
    12241 ttgccaaagg atattacacc ttatctgatt atgataaatt gacaaagtgg tataggggta
    12301 tcttgaaatc acagggtatc gatatattag atatctatta ttgccctcat catccagatg
    12361 gaattggccc tgaatatcga tgtgattgtc cgtgccgcaa acctaatacg ggtatgttcg
    12421 agtctgcagc tcgtgattat tccattgact taaaacaatc ttttattgtt ggtgataaac
    12481 tgggtgatgt agaagccgga ttaaagtttg ggttgggccg agttttttta gttgagacgg
    12541 gccatcagat tcctgctgta ggttatgcca catatccagt ttattctgat ctgttatcta
    12601 ttccattatg aaaaacacaa tcaccagatt tttgaagaaa gcttttgtta aattcaggta
    12661 taccaggctc gcacgtaagc tttggaaatt atttgccctc atggttaacg ctcattaccc
    12721 aaggcggtta ttaattaaag cgttgaacgt taatgctgaa caaaatgcaa atgaatttac
    12781 tgtttttcca aaaattttaa agtcaagttc agataaaaat gcgctagtca ttatgccttt
    12841 ttatggaaat gatgccgtcg ggaaaaatat tgatacaaaa attgcgacat taaaatccct
    12901 aggattcaca attcacgcta ttgttttcaa taattcacct tgggattcaa atagtgttga
    12961 ttgggattat acttataata taaaatgtcg gaacggaaag ttcggcactc taagacacga
    13021 tgtcaatcag caaataattc ctgatggaaa taaaattgac gattggcttg atgatgaaat
    13081 atgtcaattt gttgctgcac tttctgcgat gaataattat cagattgcaa ttgttaatta
    13141 tgtcttcctg tcaaaattgt gtttatatct taaacctaat acagtctcag tgatcgatac
    13201 tcacgatgtt tttgctaaga ggaacactcg aatggcaaaa attggtattt cacaagataa
    13261 attctatttc tctacatcga agaaagaaga aaccattggg ttatcaagag ctaattatat
    13321 atttgctatt caagaagcag aaggccgtta cttcagggag aatgttagtt cccaagtcat
    13381 tgttcagcca cctattctgg acgtaaactt tattgattat gtcccaacat ccaataaaaa
    13441 gatcgttgtt ggctttatgg cctctgggca ctatccaaat gtcgttgcga tcaacaattt
    13501 tatcgatagc ttaagtaaac ttgatcataa tgtaagactc gatatttcag gaacaatttg
    13561 cggagctctt gaaggtagac agtaccctgg ttttgttaat atcctcggtt tttgtgagag
    13621 ccttgataag ttctaccatt cctgcgatgt aattatcaat ccagatgaat tactttcagg
    13681 gttgaaagtt aaatgtctgg aggcgctttc ttatggtgtt ccattagttt caactaaagc
    13741 tgctatggaa gggattgagt cgacagaaga gtaccatcag atcgaatctg cgcaaaagtg
    13801 tgctgagttc attacatcgc ttaaaaaaga tgagctcatt aacatggcta ctcatagtcg
    13861 aaatgtcttt gccaacttta atcagcgcta taatttccaa tccactttgc gaaaggtttt
    13921 gaaagacaat gggtgatgat atctttaaaa tttccgttat tttacctgta tacggcggcg
    13981 aagtttattt agagcaatgt ctcgacagtg ttctgtctca aacatataag aatctggaaa
    14041 taataatagt caatgacggt agccctgatg cttgccctca gattattgat cgatacgctt
    14101 cgagcgatac aagaatcatt gctatccata aaaaaaacgc aggttacgga gctgcaatca
    14161 actctgggct agatgttgca agcggcgatt ttatttctat catcgaaaca gacgattggg
    14221 ttcagcttga tatgtttgag cgtctaatag acgcttataa taaaatcccg aatccggtca
    14281 ttaaagcaag tttcaataga ataagtaatg aagttgtaat caatactcag tcccttgcgc
    14341 atttatgtac atttgataat gataacttgg cagaaattgt accagaaaat tcagttgagc
    14401 ttttcttgct tgaatcatca atctggactg gcttgtatag aagagatttt cttgaagaaa
    14461 atcatattcg cttctatgaa agtcctgggg cttcatatca ggatatgccc tttaaattca
    14521 tcacctatgc ctctgtagaa aagataactc ttttgaatgt gcctgtttat aactacaggg
    14581 tcatgaacgt gggctcatcc agtgctagtg ctgacaaggc attaatatct tttaataatt
    14641 atgatattat aaaaaaacac cttcttagtg ttggaacgtt tcaaaaatac ctgaatcatt
    14701 tttattttca ccatcttttt gatttagttt tccattattc tcgtttgaga ggcgatggat
    14761 tgaagtcata tcaggaagct gctattgctg tttttgaaca ggctaaagaa gaaggtttcc
    14821 agccagtaac ttctaatgtt tcattttcct ccgatacaaa tgactattat tataatcatg
    14881 ttcttccaat ttataatgag ttgatgagta acaggattat aaaaacagtt cagacaagaa
    14941 acaggattaa aaagaaagtc gtttccaaac tacgttttat tactaacaaa ttaataattg
    15001 aaccaattat taatgctgtt tcatcaaaaa tggattcctc ctcatcttta ctttccaaac
    15061 attttcggga ggagttagat tcttcatttt tgaagatgtc gaaagaactt actgataaag
    15121 tcgatgtcat ttcaggacag aataaaaatg gttctgtact aataaaagta gcgcctacta
    15181 accagtttta ttattacatg aaggtaaatt cctctcggat ctctaaacta cgtgaagaat
    15241 tcaaacgcgg ccttgatgaa tttagccttc aaaatgagag gaaattattt ggtttttatg
    15301 aattactgcc atactttgaa catcaaggca ttgagttgga attaccttta tctttaacat
    15361 tatttacgga tgaagataga gttatattgt caaatattga ttcaatctta cgtcacgaaa
    15421 aagaattaat tcagcatctt gatctatctg aattaccggt tactctagca accaactatt
    15481 tcaaagctgg cttgaagtat cttccaggcc gattcactga agaattcaaa ggctctgttg
    15541 ctatagattg tggggcttgg gttggtgata cagctatcat gttcgctagc tttggattta
    15601 aagaagtact tgccttagaa cctgtagctg ataattataa ctgtatggtt cggaatcttg
    15661 agcgtaatca tcaatattta aatgatacta ttaaaccctt aaatgttgct gtcagcaatg
    15721 tatctggcga actttcgatg atgaaagttg gggatgatgg agtaggctca tgtgttgttg
    15781 aagacgagca gtctgacatt aaagttcaat cggtcactat tgatagtctg acgtttgaag
    15841 atcgtgttgg tttgattaaa ttcgatattg aaggctatga gattaatgcc cttaatggtg
    15901 caatcgagac aatcaaaaaa cacaagcccg tgttgctgat ttctgtttat cacttgtggt
    15961 tgcagccaga gcaaattttt gaatgtaaga aatttgttga aaatctcaat atgggttatc
    16021 aattcaagtt tgttcacctc cagcctgagc gtgatctggt gtatgaatac atgcttgtgt
    16081 gttggtgatt tgtaatagtc tttattttga ttcacaaaca aatcagggat gatttgtttt
    16141 gctttattta aaactgatat tttcttcgaa gtataagatg acgtgctgag gttttaaatt
    16201 ttaacaggat aatagcttaa ggaaggagat gtgagtttta aatatgaaaa taaagatatg
    16261 ttattttgtg aactccgctt ggtatttcga attacattgg ttagatcgtg ccttatcagt
    16321 tctggaagca ggatatgatg tctatatttt tgcgaattat tctgacaagt ctattctgga
    16381 tcgctttact agtttaggat ttaagtgtat tgatagtaaa ataaaagagc aaaatatcaa
    16441 tcctgttgtt ttcttttgcg atataactcg ctcatttaga acattgaata aaattaatcc
    16501 tgatattgtg catagccgca cgattaaacc tggtgtgatt agttgtttat gggccagaat
    16561 ccgaaacaaa aaaatggtct atagttttgt tgggttaggt agagtttttg aaagcaataa
    16621 ggtcatttac caaatggtta agttcttaat tgctaatatg tatagaagat ttttcttaaa
    16681 tattgattgt tgtatcctct ttgaacataa aaaagatcag caaaaaataa ttgaactatt
    16741 agatattcca aaaaataaaa ctgaagttat tgatggcgca ggtattaata tagactattt
    16801 ttgttatagt acaccaccta ataataccaa ggttaaagtt ttttttgcaa gtcgcatgct
    16861 ttggagtaaa gggctacgca cgttaattga tgctagtaga attttaaaat tacaaggcat
    16921 cgaatttgag atattagttg cgggcattct tgttgacaat gatcgcgacg ctataagtat
    16981 aactcagata gaagagtggc ataactccgg tgatatcatt tggctgggca agcgtagcga
    17041 tatcaaggaa ttaattgaaa gtgtggatat agtcgctttg ccatctgttt actctgaagg
    17101 tattcctcga attcttttag aagccggtgc aatcggtcgt cctgttataa gttttgacac
    17161 tggtggttgt gggagtttaa tacttgacgg ttataacggt ttccttgtgc ctaaaggaaa
    17221 tgtgaaccta ttttctcaga agcttggtat ccttattagc gatcctcttg agcgcactaa
    17281 gatggggcag aatgccagaa agcgagtaga ggaaaagtat tcatctaccg ttgtcatacg
    17341 aaaaaccgtt caaatctata ataaactcac aatgcaagaa gtgctctaat attgagcaac
    17401 aacttatctg agcttgtcgc tatgcgtttt tttagttact tatgacagtt attaatttca
    17461 ctcaaacatc tatttcttta tacaacttgt cgttctccta atatataatt tcttaaattc
    17521 tgtctgttca tagacagata ctacctgaca ggagtatgta atgtctaagc aacaaatcgg
    17581 cgtagtcggt atggctgtga tggggcgcaa cctggcgctc aacatcgaaa gccgtggtta
    17641 taccgtctct atcttcaacc gctcccgtga aaaaaccgaa gaagttgtcg ctgagaatcc
    17701 aggcaaaaag ctggttcctc actacacggt caaggagttc gtcgagtctc ttgagacccc
    17761 acgtcgtatc ctgttaatgg tgaaagcagg cgcgggcacc gatgctgcca tcgattccct
    17821 gaaaccttac cttgataaag gtgacatcat cattgatggt ggtaacacct tcttccagga
    17881 taccattcgt cgtaaccgtg agctgtctgc tgaaggcttt aacttcatcg gtaccggcgt
    17941 atccggcggc gaagagggcg cgctgaaggg cccatctatc atgcctggcg gccagaaaga
    18001 agcgtatgag ttggttgcgc ctatcctgac caagattgct gctgtagctg aagacggcga
    18061 gccttgcgta acctacatcg gtgctgacgg tgcgggtcat tacgtgaaaa tggtccacaa
    18121 cggtatcgaa tacggcgaca tgcagctgat tgctgaagcc tattctctgc tgaaaggcgg
    18181 cctgaacctg tctaacgaag agctggcaac caccttcacc gagtggaatg aaggcgagct
    18241 gagcagctac ctgatcgaca tcaccaaaga catcttcacc aaaaaagatg aagacggtaa
    18301 atacctggtt gatgtgatcc tcgacgaagc ggcgaacaaa ggcaccggta aatggactag
    18361 ccagagctct ctggacctgg gcgaaccgct gtcgctgatc actgaatctg ttttcgcgcg
    18421 ctacatctcc tccctgaaag accagcgcgt ggcggcatct aaagtgctga ctggcccgca
    18481 ggctaaactg gctggcgata aagcagagtt cgttgagaaa gtgcgtcgcg cactgtacct
    18541 gggtaaaatc gtctcctacg cgcagggctt ctctcagctg cgtgccgcgt ctgacgagta
    18601 caactgggat ctgaactacg gcgaaatcgc gaagatcttc cgcgcgggct gcatcattcg
    18661 tgcacagttc ctgcagaaaa tcaccgacgc ctacgctgaa aacgcgagta tcgccaacct
    18721 gctgctggca ccgtacttca aaaatatcgc tgatgaatac cagcaggcgc tgcgtgacgt
    18781 ggtggcctat gctgtgcaga acggtattcc ggtaccgacc ttctctgcag cagtggcgta
    18841 ctacgatagc taccgcgctg cggtactgcc ggcgaacctg atccaggcac agcgcgacta
//