LOCUS       AB811617               19935 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain: H710C.
ACCESSION   AB811617
VERSION     AB811617.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 19935)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..19935
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H710C"
                     /db_xref="taxon:562"
                     /note="serogroup:O41"
     gene            <1..904
                     /gene="wcaM"
     CDS             <1..904
                     /gene="wcaM"
                     /codon_start=2
                     /transl_table=11
                     /protein_id="BAQ00888.1"
                     /translation="TPSYARDFITXIIGANITNCKFSDLQGDAIEWNVAINDSDILIS
                     DHIIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVEN
                     GKHFVIRNIKARNITPDFSKKAGIDNATIAIYGCDNFLIDNIEMTNSAGMLIGYGVIK
                     GKYLSIPQNFRVNNIQLDNTHLAYKLRGIQISAGNAISFVALTNIEMKRASLELHNKP
                     QHLFMRNIKVMQESSVGPALTMNFDMRKDVRGVFMAKKETLLSLANVHAVNESGQSSV
                     DIDRINHHIVNVEKINFKLPERGE"
     gene            1067..1972
                     /gene="galF"
     CDS             1067..1972
                     /gene="galF"
                     /note="O041_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00889.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEMRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2321..3640
                     /gene="wzx"
     CDS             2321..3640
                     /gene="wzx"
                     /note="O041_02"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="BAQ00890.1"
                     /translation="MHIKLNKNISEVLSFSSIEKIAKNSGWLLMERCTRLTLGLLVST
                     WIARYLGPDQYGVLSYVIAFIAFFQAILPLGMDGIIVRDISKNEKDSGAILGTIIITR
                     FTLGLILWFAIIILTTIIYSLKSEYTLLSAIIGASLIFQAADTIDLWFQSQSQSKRTV
                     VAKLLAYISVNLLKIGMLIFKCPLYAFAIATLLEFIFSSIGLIIAFTRFRPTVKLAFS
                     SLIIKKFLGESWPFLISSIAIIIYMRIDQMFIKYYLPLNDLGIYSAMLPLATLWSFIP
                     MTLSISVSPFLTKAKMESEEKYQKILCFTFKLFSMLGWLICIPVCVFSDYIVSLLYGP
                     QYQTGAVVLSILIFTNLFIYQGVAQSLWIINERKGKLSLLKTILGAIVCIVANLILIP
                     KYGIIGAAISAVLAQFTSAIMANIVMAPRILILQIQSLLFIPLRKVN"
     CDS             3640..4569
                     /note="O041_03"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00891.1"
                     /translation="MESKVSVYAPVILFVYARYEHTKKTIEALADNYYATETELIIYS
                     DYWHDENDKENVNKVRRYIKSIKGFKSITIIERETNYGLAKNIIEGVTDVCNKYERVI
                     ILEDDLLTSRFFLKYMNHALEKYELNEEVWHISGWNYPIDFNSNKASFLWRVMNCWGW
                     ATWSNRWRYFEKKPSQIISEWDAEKIKAFNLDGYHDFFEQIIMNYEGRKNTWAIFWYA
                     TIFINNGLCLNPINTYVKNIGYDGSGQNCGVKDIYKSKVSQFYIDSFPDILEENELAV
                     KEIKKFFKKQEPSVFRKIAREIRNYLMTLCKIK"
     CDS             4581..5837
                     /note="O041_04"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00892.1"
                     /translation="MKILILSHSDISGGASIAAYRLHTALLKNNIYSRMMVRVKKTDD
                     FTVIGPKGSVQKILNKIRSPLGNCINGLLKTKKTGFISGNWMPSGWAEKINKMDIDIV
                     HLHWVGAETLSIEDIGRINKPVIWTLHDMWPFCGIEHYAPDLLESRWRNNYENHSFSS
                     FIDLDFIVWKRKKNSWNNNISIVSPSTWLYDCAKHSSLFENNKHVLIPNALDLSVFKP
                     LDKSYCREILNIDNDKKIILFGAFGGGTDKRKGYDLLVKALELIAKDSNTFKIQCLVF
                     GQSTPEEKIDLPIDIKWLGHIYDNTTLSLIYNSANVMVVPSRQDNLPQTATEAQACGC
                     PVVAFDCTGFPDIITHKETGYLAKPYDFVDLARGILWVLNNKDVEINLSSNAVHKAHK
                     IWSEDQVVSEYIALYQNIINEKTRNV"
     gene            5856..7052
                     /gene="wzy"
     CDS             5856..7052
                     /gene="wzy"
                     /note="O041_05"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="BAQ00893.1"
                     /translation="MSKLKSKYIRNNYARPGNDIVASIISLCVIITLHPLISLVLLSL
                     INIFTRLSNKICYLYCLVYSILIVNREYLIEFNERSGDDTFRYIPFIKNIATFSFDKA
                     LTAESDIFSIEPLSRAYWWLLSVLGVNINVILLLQVFCWTTCLMVLAIKISERYAMII
                     LCIGICFFSYTIPYTFFHLFRQAWGLSFFILYLCNWDKPGRFAFILLAGLSHLMFIPL
                     LIFMEISRKGILILTSKYFPLLAAIFLIALYLTYNALLTKIGMYSEGENINYSPFKSL
                     IYSLFFFSLLMLYNKYEEKIFHLSNIKFNISLTLISFYLFGLYIPLADIVNRYILLLS
                     PLVIMFLTITKSRFLLLLFLLAALIKLSIHLFDVDGNIYQFTMRGYLDFYNVMDALYF
                     YLERKI"
     CDS             7049..7798
                     /note="O041_06"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00894.1"
                     /translation="MKPLITVITVVYNDSKGLTKTINSLKLQTNLTNVEFIVVDGNSS
                     DSTIEIIKSSKVITKYIIEDDHGIYDAMNKGIDLATGNWILFLNAGDVFYNDDVLRKL
                     NDTIMNLHESINFIYSDYLSGGVIYKQFLSLDFLASHMINHQNIVYKTELLKDKGYST
                     KYKFCSDYKHILDNYFIINPYKTGYIIAAFDNTGVSSQVVNKYKMWLERLNAVWSSKL
                     SLQAKIKLSKRGWVALPYQFIRFVIIKMRML"
     CDS             7795..8652
                     /note="O041_07"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BAQ00895.1"
                     /translation="MNYNVELFIGVCVTYDDFNKYKLQLLSSLKNLYNSFAGDCSVYI
                     VIQSERCSFDYRYSYPTDWIEFYETDYFGISNARNLCIEACLRKNAKFIIFHDASIYW
                     TKSAAEFIHRFRNNIETPRINLLFDKNYHMQHEFNHPLDIQNIRIEKCNPIYNSYVGG
                     FLFRVSKIKELRFHLGFGPGKYTKCKSGEDVLFLFEYFERQNITLYPINRKIAVIHPP
                     RPSDYSKHLLYAYGQGALFRFLVHKYKRMSLFYDLILFFGNALVRCLLFKKKSFQILY
                     NRLKGFIGV"
     gene            8654..9772
                     /gene="gmd"
     CDS             8654..9772
                     /gene="gmd"
                     /note="O041_08"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="BAQ00896.1"
                     /translation="MKKALITGITGQDGSYLAEFLLDKGYEVHGIKRRASSFNTERVD
                     HIYQDRHNQNPNFFLHYGDLTDSSNLIRLIKEIQPDEVYNLGAQSHVAVSFESPEYTA
                     DVDAMGTLRLLEAIRICGLEKKTRFYQASTSELFGLVQEIPQRETTPFYPRSPYAVAK
                     MYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANISQGIEKCLYLG
                     NMDSLRDWGHAKDYVRMQWMMLQQDHPEDFVIATGKQISVREFVRMSAKEVGLELEFS
                     GQGVDEIATVVNKTSDCAIGVSIGDVIVRVDPRYFRPAEVETLLGDPAKAKKVLGWEP
                     EITVEEMCAEMVASDLAKAKQHALLKSHGYDVAVSLER"
     gene            9776..10741
                     /gene="fcl"
     CDS             9776..10741
                     /gene="fcl"
                     /note="O041_09"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthetase"
                     /protein_id="BAQ00897.1"
                     /translation="MTKKRIYVAGHRGMVGSAICRQLSLRDDIELVVKTHKELDLTVQ
                     KDVDAFFEQEKIDQVYLAAAKVGGIYANNTFPAEFIYQNLMIESNIIHSAHKAGIQKL
                     LFLGSSCIYPKFAEQPMNESELLTGILEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGINDNFHPENSHVIPALMRRFHEAKESGAPEVVVWGTGTPMREFLYVDDMA
                     AASVHVMELDEAIYQQNTQPMLSHINVGTGVDCSIREMAETMASVVGYQGKIVFDATK
                     PDGTPRKLMDVTRLKNLGWQYRYNLHEGLSLTYKWFIENINSFRG"
     gene            10744..11205
                     /gene="gmm"
     CDS             10744..11205
                     /gene="gmm"
                     /note="O041_10"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="BAQ00898.1"
                     /translation="MNKRLECELFKTIVEHTPLISIDLIIRNDKGEALLGQRLNRPAQ
                     NYWFVPGGRIYKDESFEVAFNRITFEELGVQISLNDALFLGVYEHFYNDNFSEAEFST
                     HYVVHGYEIQLNPQQLHLPTVQHNSYKWFDVVTLLNSTIVHQYTKNYFIPR"
     gene            11211..12617
                     /gene="manC"
     CDS             11211..12617
                     /gene="manC"
                     /note="O041_11"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="BAQ00899.1"
                     /translation="MLLPVVMAGGSGTRLWPLSRTLYPKQFLSLNSRLTMLQETLRRL
                     DKVEHKPALVICNESHRFIVAEQLRKEGLKHSGILLEPVGRNTAPAVALAALQAMVTG
                     DDPILLVLAADHEIQDEDNFIAAVLAAKNFAEQGKLVTFGIVPTSPETGYGYIKSGES
                     LDEQGYKVAAFVEKPDLHVAQRYISEGGYLWNSGMFMFRASVFIDELKKFRPDILASC
                     QRSLSSSIQDLDFIRLDNASFSCCPEESIDYAVMEKTAEAVVVPLNAQWSDVGSWSAL
                     WEISSKDQSGNAIRGDVLVEDATDSYLYSQHRLIGAVGVKDLVVVETKDAVLVAHKDK
                     VQQVKNIVAQLKKNNRTEYLQHREIYRPWGSHDTIAEGERFQVKHVIVLPGHITAKQI
                     HYHRTEHWVVVSGTAKVHLEDKTYLVSENESTYIPVGVPHAIENPGKIPLEIIEVRSG
                     VYLEEDDVIRVSSSGVGY"
     CDS             12617..13363
                     /note="O041_12"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00900.1"
                     /translation="MRISIITATYNSEKTLLDTLLSLEKQTHPDIEYIVIDGASKDNT
                     IKLIKSNCTRVSKIICEPDNGIYDALNKGIQAASGDVIGFLHSDDLLAYDDVIADIAK
                     TFESSGCDAVYGDLEYVAQNDTTKRIRLWKSGSFSRLKMKLGWMPPHPSFYMKRDCYG
                     QFGCFSLDYRISADYDSLLRYILKQRISIAYLPQVLVKMRVGGISNRSLSSMVNKSME
                     DIRVMKQNGIFWPIALAYKNLSKLPQFIKK"
     gene            13369..14793
                     /gene="manB"
     CDS             13369..14793
                     /gene="manB"
                     /note="O041_13"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase"
                     /protein_id="BAQ00901.1"
                     /translation="MLNAKKIITDSNIAFGTSGARGLVVDFTHDVCAAFTHAFLSVID
                     DKYNLNKVALAIDNRPSSYEIAQACALAIKQHGFTVEYHGVIPTPALAHYSMQKNIPC
                     IMVTGSHIPFDRNGLKFYRPDGEITKEDELAIVNSEYVFSPVDVLPHLELSTQGADCY
                     LKRYVSLFNSDILKGKKIGIYEHSSAGRDLYAPLFNQLGAEVISLGRSDEFVPIDTEA
                     VSDEDRILAREWSKKYNLDAIFSTDGDGDRPLVADENGEWLRGDILGLLTAIELNIKA
                     LAIPVSCNTAIEQSNKFASVQRTKIGSPYVIAAFADLAKQFDSVAGFEANGGFLLASD
                     LQINGKELNSLPTRDAVLPALMLLIASRNSTISQLVNNLPQRFTWSDRVKDVPSESSQ
                     HIIKNAILSPNNFFNSLGYESLSCSAIDETDGARFTLNNGDIIHLRPSGNAPELRCYA
                     EASNENQAKQYVTKVLGNITSLIS"
     gene            14979..16385
                     /gene="gnd"
     CDS             14979..16385
                     /gene="gnd"
                     /note="O041_14"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00902.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKEQRVAASKVLSGPKAQPAGDKTEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            16634..17800
                     /gene="ugd"
     CDS             16634..17800
                     /gene="ugd"
                     /note="O041_15"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00903.1"
                     /translation="MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKKQSP
                     IVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIR
                     DVTEINPNAVMVIKSTIPVGFTKSIKERLGIDNLIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNISTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            17943..18923
                     /gene="wzz"
     CDS             17943..18923
                     /gene="wzz"
                     /note="O041_16"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00904.1"
                     /translation="MMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIITVIVAIA
                     LAIGYLAVAKEKWTSSAIVTQPDVGQIAGYNNAINVIYGSAAPKVSEIQSMLIGRFST
                     TFSALAETLDNQEQAEKLTIEPSVKNQPLPLAVSYVGETPEGAQKQLAKYIQQVDDQV
                     NEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVSKPQI
                     QQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIESLKVDDLDIH
                     SYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNYNAK"
     gene            complement(19020..19631)
                     /gene="hisI"
     CDS             complement(19020..19631)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ00905.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TLESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPVGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPQTSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
ORIGIN      
        1 tacgccatct tacgccaggg atttcataac cangattatc ggtgccaaca tcaccaattg
       61 taagttcagc gacttacagg gggacgctat tgaatggaac gtggcgatta acgacagtga
      121 tattttgatc tccgaccaca tcatcgagcg catcaactgt actaacggca aaatcaactg
      181 gggcatcggc ataggccttg caggaagtac ttacgataac aactacccgg aagaccaggc
      241 agtaaaaaac tttgtcgtgg cgaatatcac gggatcggac tgtcgacagc tgatacacgt
      301 tgaaaatggc aaacattttg ttatccgtaa tatcaaagcc cgaaatatca cgccggattt
      361 cagtaagaaa gctggtattg ataacgccac gattgctatt tacggctgtg acaatttttt
      421 gattgataat atcgagatga ctaatagtgc cggaatgtta atcggttacg gagtcattaa
      481 aggtaagtat ctctcaatac cgcaaaattt ccgggtgaat aatattcaac tggataacac
      541 ccatcttgct tataaattgc gcggcattca aatttccgca gggaatgcta tctcattcgt
      601 ggcgttgacc aacattgaaa tgaagcgtgc gtcactggag cttcacaaca agccgcaaca
      661 tctttttatg cgaaatatca aggtgatgca ggaatcctct gttggaccag cattgaccat
      721 gaacttcgac atgcgtaagg acgttcgtgg tgtctttatg gcgaaaaaag aaacactact
      781 gtctcttgca aatgttcatg cggtgaatga aagtggacaa agttcagtcg atatcgacag
      841 gattaatcac catattgtta atgtggaaaa gattaacttt aagctgccgg aacgggggga
      901 gtagatttgc gaccattcct ggataaatgg agccatactt aggaataacg ctactgcaat
      961 tttgagcgaa gcggcgtaac atcggaagta aatcagtaat caattcaggg gaattgatgc
     1021 tggcgaaaaa aatcgaacaa gctataattc agcaaccatt ttacaggtgg atgaaataat
     1081 gacgaattta aaagcagtta ttcctgtagc gggtcttggg atgcatatgc tgcctgccac
     1141 taaggcgatt cctaaagaga tgctaccgat cgtcgacaag ccaatgattc agtacattgt
     1201 tgacgagatt gtggctgcag ggatcaaaga aatcctcctg gtaactcatg cgtccaagaa
     1261 cgcggtcgaa aaccacttcg atacctctta tgaattagaa tctctccttg aaatgcgcgt
     1321 taagcgccag ctgctggcgg aagtacaatc tatttgccca cctggtgtga ccattatgaa
     1381 cgtgcgtcag ggcgaacctt taggtttagg ccactccatt ttgtgcgcca gacctgccat
     1441 tggcgacaac ccatttgtag tggtgctacc agacgttgtt atcgacgacg ccagcgctga
     1501 cccgctgcgc tacaaccttg ctgccatgat tgcgcgtttc aacgaaacgg gccgcagcca
     1561 ggttctggca aaacgtatgc cgggtgacct ctctgagtac tccgtcatcc agacgaaaga
     1621 accgctagat cgtgaaggta aagtcagccg cattgttgaa tttatcgaaa aaccggatca
     1681 gccgcagacc ctggattcag acattatggc cgttggtcgc tatgtgcttt ctgcagatat
     1741 ttggccggaa cttgaacgca ctcagccagg tgcatgggga cgtattcagc tgactgatgc
     1801 cattgccgaa ctggcgaaaa aacagtctgt tgatgccatg ctgatgacag gtgacagcta
     1861 tgactgcggt aaaaaaatgg gttatatgca ggcatttgtg aagtatggac tacgcaacct
     1921 gaaagaaggg gcgaagttcc gtaaagggat tgagaagctg ttaagcgaat aatgaaaatc
     1981 tgaccggatg taacggttga taaggaaatt ataacggcag tgaagattcg tggcgaaagt
     2041 aatttgttgc gaatattcct gccgttgttt tatataaaca atcagaataa caacgagtta
     2101 gcaataggat tttagtcaaa gttttccagg attttccttg tttccagagc ggattggtaa
     2161 gacaattagc gtttgaattt ttcgggttta gcgcgagtag gtaacgctcg taacatcgta
     2221 gacatgcatg cagtgctctg gtagctgtta agccaggggc ggtagcgtgt gaaatattaa
     2281 tcaataagaa aaacagacga ataatttggc ctgaaatttt atgcatatta aattaaataa
     2341 aaatatatca gaagtattat ctttctcttc cattgaaaaa atagctaaaa atagtgggtg
     2401 gctattaatg gaaagatgta ctagattaac actaggttta ttagttagta catggatcgc
     2461 tcgttatttg gggccggatc agtacggagt tttgtcttat gtaatagcat ttatcgcgtt
     2521 cttccaagct atccttcctt taggaatgga tggtataata gtccgagata tctcaaaaaa
     2581 tgagaaagac tctggtgcta tacttggaac tataattatt acacgattca cacttggatt
     2641 aatattatgg tttgcaatca taattttaac gactattata tactcactaa aaagtgaata
     2701 tacattatta agtgccataa tcggagcatc acttatattt caagccgcag acacaataga
     2761 tttgtggttc caaagtcaaa gtcaaagtaa aagaacagta gtggcaaagt tgcttgctta
     2821 catatctgta aatttactta agataggaat gcttattttt aaatgccccc tatatgcttt
     2881 tgcaattgca acactccttg aatttatctt ttcttccatt gggctaatca ttgcttttac
     2941 gcgttttcgt ccaactgtta aattggcctt ttcatcttta attatcaaga aatttttagg
     3001 tgagtcatgg ccatttctta ttagtagtat cgcaataata atttatatgc gaattgacca
     3061 aatgtttatc aagtactatt tgcctctaaa tgatttggga atatactcag caatgttacc
     3121 acttgctacg ctttggtcat ttattcctat gactctaagc atcagtgtat ctccttttct
     3181 tactaaagca aaaatggaaa gcgaagaaaa atatcagaaa atattgtgtt ttacattcaa
     3241 gttattttca atgttaggat ggttaatttg tattccagtg tgtgtctttt ctgattatat
     3301 agtttctcta ctttatggtc cgcaatatca aacaggtgct gtagtcttat caatattaat
     3361 attcactaac ttatttatat accaaggggt ggcgcagtca ttatggatta ttaatgagcg
     3421 aaaagggaaa ttaagtttat tgaaaacaat attaggcgca attgtatgta tagttgctaa
     3481 tttaatatta attccgaaat atggcattat tggtgcagct atatcagcag tattggcgca
     3541 gtttacatca gctataatgg caaatattgt aatggcacca agaatattaa tattacagat
     3601 acaaagcctg ttgtttatac cgttgagaaa ggttaattaa tggaatctaa agtaagtgtg
     3661 tatgctcctg taatcctatt tgtttatgct agatatgaac atacaaaaaa aacaattgaa
     3721 gcgttagcag ataattatta tgcaactgag acggaactta tcatttattc tgattattgg
     3781 catgatgaaa atgataaaga aaatgttaat aaagtcagaa ggtatattaa aagtataaaa
     3841 ggatttaaat caattacaat aattgagagg gagactaatt atggcttggc aaaaaatatt
     3901 atcgagggag tgacagatgt ctgtaacaag tacgaacgag tgattatttt agaagatgac
     3961 ttgttaacat cgagattttt tttaaagtac atgaatcacg cattggaaaa atatgagtta
     4021 aatgaagaag tatggcatat aagcggttgg aattatccaa ttgattttaa ctccaataaa
     4081 gcctcatttt tatggagagt gatgaactgt tgggggtggg cgacgtggtc aaaccgatgg
     4141 cgttattttg aaaaaaaacc ttcacaaata ataagtgaat gggatgctga aaaaatcaaa
     4201 gcattcaatt tagatggtta tcatgatttt tttgaacaaa taataatgaa ttatgaaggc
     4261 agaaaaaata cctgggcaat tttttggtat gccacaatat ttattaataa tggtctgtgt
     4321 ttaaacccga taaacacata tgtcaaaaat ataggatatg atggctcagg tcaaaactgt
     4381 ggtgttaaag atatttataa gagtaaggtg tcacaatttt atattgattc gtttcctgac
     4441 atactggaag agaatgaatt ggccgttaaa gaaataaaaa aatttttcaa aaaacaagag
     4501 ccttctgttt ttagaaaaat cgcaagagaa atccgaaact acttaatgac attatgcaaa
     4561 ataaaatgaa ctggtaagtt atgaaaatcc taatattatc acactctgac atctctggtg
     4621 gggcatcaat agcagcttat agactccaca ccgcattgct gaaaaataat atttattcta
     4681 gaatgatggt aagggtaaag aagactgatg actttacagt tattggtcct aaagggagcg
     4741 ttcaaaaaat tttgaataaa atccgctcac cgcttggtaa ttgtatcaat ggattattaa
     4801 aaacaaaaaa aacaggtttt ataagcggaa attggatgcc atctggatgg gcggaaaaaa
     4861 ttaataaaat ggatattgat attgttcatc ttcattgggt tggggcagaa acattatcaa
     4921 ttgaggatat tggtagaata aataaaccag ttatttggac tttgcatgat atgtggccat
     4981 tttgcgggat tgaacattat gccccagatc ttttagaaag tagatggcgt aataattatg
     5041 aaaatcattc attctcttca tttattgatt tagatttcat tgtatggaaa agaaaaaaaa
     5101 attcatggaa taataatatt agtattgttt ctccaagtac ttggttatac gattgtgcaa
     5161 aacatagcag tttatttgaa aataataaac atgttctaat tccaaatgca cttgatcttt
     5221 cagtttttaa gccattagat aagagttatt gtcgagagat tttaaatata gacaatgata
     5281 agaaaataat tctttttggt gcgtttggcg gaggaactga caagcgcaaa gggtatgatt
     5341 tgttagttaa agcattagaa ttaatcgcta aggacagtaa caccttcaaa attcaatgct
     5401 tagtctttgg acaaagtacg ccagaagaaa aaattgatct tcccatcgat ataaaatggt
     5461 taggccatat atatgataat acaacattat ctttaattta taactcagcg aatgtaatgg
     5521 ttgttccatc aagacaagat aatttgccac aaactgctac agaagcacaa gcttgtggtt
     5581 gccctgtcgt ggcatttgat tgcactggat ttccagatat aatcacacac aaggaaacag
     5641 ggtatctagc taaaccatac gattttgtag atttagctag ggggatatta tgggttctaa
     5701 ataataaaga tgtggaaatt aatctaagca gtaatgcagt acataaagct cataaaatct
     5761 ggtcagaaga tcaagtagtt tctgaatata tagctctata ccaaaatatt attaatgaga
     5821 aaactcggaa tgtttaatta tagggcggat tacatgtgag taaacttaaa tccaagtata
     5881 taagaaataa ctatgccaga cctggtaatg atatagttgc ttctataatt tcattatgcg
     5941 tgattattac actacatcct ttaatttctt tagtacttct gtcactaata aacattttca
     6001 cgcgtctaag taataagata tgctatcttt actgcttagt atattcaata cttattgtaa
     6061 atagagaata tctgattgag tttaatgagc gtagtggtga tgatactttt cgatatatcc
     6121 catttataaa aaatatagca acattttcat ttgataaagc attaactgca gaatctgata
     6181 tattcagcat tgagccatta agtcgagcat attggtggtt gctatcagtt ttaggagtta
     6241 atatcaatgt gatattattg cttcaagtct tttgttggac aacttgtttg atggttttag
     6301 ctataaaaat aagtgaaaga tatgcaatga ttattctatg cataggcatt tgcttttttt
     6361 catatacaat tccatacact ttctttcatt tatttaggca ggcatgggga ctatcattct
     6421 ttattctata tttgtgcaat tgggataagc cgggtagatt tgcatttatt ctattagccg
     6481 gattgagtca tttgatgttt attccattat tgatttttat ggaaatatca agaaaaggga
     6541 tattaatatt aacatctaaa tattttccgt tattggctgc tatcttcctg attgcattat
     6601 atttaacata taatgcattg ctaacaaaaa ttggaatgta ttctgaaggt gaaaacataa
     6661 actattcacc atttaaatct ttaatttatt ctctcttttt cttttcttta ctgatgcttt
     6721 ataacaaata tgaggaaaaa atatttcatc tttcgaatat taaattcaat ataagtctca
     6781 cattaatttc cttttatttg tttggtcttt atattccgtt agcagatatt gttaatcgat
     6841 atattttatt gctatcaccg cttgttatta tgtttcttac cattactaaa agcagatttc
     6901 ttttattgtt atttttgtta gctgcattaa ttaaattgtc gatccatttg ttcgatgtag
     6961 atggtaatat atatcagttc acaatgaggg gttatcttga tttttataat gtaatggatg
     7021 cgttgtattt ttatttagag agaaaaatat gaaaccatta ataaccgtga taacggttgt
     7081 ctacaacgat agtaaaggtt taacaaaaac tataaattca ctcaagctac aaactaattt
     7141 aacaaatgtt gagtttattg ttgtagatgg caactcgagt gattcgacaa ttgaaataat
     7201 aaaaagttct aaagttataa caaagtatat cattgaagat gatcatggta tatatgatgc
     7261 catgaataaa ggaattgatt tggctacagg taattggata ctatttttga atgcaggaga
     7321 tgttttctat aatgatgatg ttttacgtaa attaaatgat actataatga atcttcacga
     7381 gagcattaat tttatttata gtgattatct ttctggtggg gttatttata agcagttcct
     7441 tagtttagat tttttagcgt cacatatgat taatcatcaa aatattgttt ataagactga
     7501 acttctcaaa gataaagggt atagcacaaa atataaattt tgctcagatt ataaacacat
     7561 attggataat tattttatta ttaatcctta taagactggc tatattatag cagcattcga
     7621 taatacagga gttagttcac aggttgttaa taagtataaa atgtggttgg agagattaaa
     7681 tgctgtgtgg tcatcaaaat tatcactgca agcaaagata aaattaagta aaagaggttg
     7741 ggtagcctta ccttatcaat tcataagatt tgtcatcata aaaatgagaa tgctatgaat
     7801 tataatgttg agttgtttat tggtgtatgc gtaacttacg atgattttaa taaatataag
     7861 ctacaacttc tttcttcttt aaaaaatcta tataactcat ttgctgggga ttgtagtgtt
     7921 tatattgtta ttcaaagtga acgttgttct tttgattatc gttactcata tccaacggat
     7981 tggatcgaat tttatgaaac agattatttt ggaatatcaa atgcaagaaa cttatgcata
     8041 gaagcttgtt taagaaaaaa tgcgaaattt attatctttc atgatgcatc aatttattgg
     8101 acaaagtctg cagcagagtt tattcacagg tttagaaata acatcgagac accgcgaatc
     8161 aacctcttgt ttgataaaaa ctaccatatg caacatgaat ttaatcatcc tttagacatt
     8221 caaaatattc gtatagaaaa atgcaatcca atttataact catatgttgg tggttttcta
     8281 tttagagtta gtaaaataaa ggaattaaga tttcatcttg gctttggtcc gggtaaatac
     8341 acgaaatgta aaagtggtga ggatgtttta tttttattcg agtattttga acgacagaat
     8401 attaccctct accctataaa tagaaaaatt gcagttatac atccaccaag gccatctgat
     8461 tattcaaagc atttgttata tgcatatggt caaggggcat tatttagatt tttagttcat
     8521 aaatataaac gaatgagtct attttatgat ttgatacttt tttttgggaa tgcacttgtt
     8581 agatgtttgc tttttaaaaa aaaatcattt caaattttat ataatagatt aaaaggtttt
     8641 attggagtat aatatgaaaa aagcattaat tacaggcatt actggtcaag atggttccta
     8701 cttggcagaa ttccttcttg ataaagggta tgaagtgcat ggcattaaac gtcgtgcatc
     8761 ttcgtttaac acagaacgtg ttgatcatat ttatcaagat cgccacaacc aaaatccaaa
     8821 tttctttctt cattatggtg acttaacaga ttcatcaaac ttaatacgtc tcatcaaaga
     8881 aatccaacca gacgaagttt ataaccttgg cgctcagtct catgtggctg tttcattcga
     8941 atcacctgaa tatactgctg atgtggatgc gatggggact ttacgtctgc tggaagcgat
     9001 tcgtatttgt gggctagaga aaaaaacacg tttctatcag gcatcaactt ctgaactctt
     9061 tggcttagtt caggaaatcc cacagcgaga aacaacacca ttctaccctc gttcgcctta
     9121 tgctgttgcg aagatgtatg catactggat tactgtaaac tatcgtgaat cctatggaat
     9181 gtacgcctgt aacggtattc ttttcaacca tgaatccccg cgtcgtggtg aaacattcgt
     9241 aacacgtaaa atcacgcgtg ctattgcaaa tatttcgcag ggaatcgaaa aatgtctcta
     9301 tcttggcaat atggattcac tgcgcgactg gggacatgcg aaagattacg tgcgtatgca
     9361 gtggatgatg ttgcaacaag atcacccaga ggattttgta attgcaacag gcaaacaaat
     9421 ttccgtacgt gaatttgttc gtatgtcagc taaagaagta ggcctggagt tagaattctc
     9481 cggacaaggt gttgatgaaa tagcaactgt tgtgaataaa acatctgact gtgctattgg
     9541 tgttagtatt ggggatgtaa tcgttcgtgt tgatccgcgt tatttccgtc ctgcagaagt
     9601 tgaaactctt cttggtgatc cagcaaaagc caaaaaagta ttgggttggg aaccagagat
     9661 tacagttgaa gagatgtgtg cagaaatggt tgccagtgat ctggcgaaag caaaacagca
     9721 tgcacttctg aaaagccatg gttacgatgt tgcagtttct ctggagcggt aaggtatgac
     9781 aaagaaacgt atctacgttg ctggtcaccg aggtatggtt ggctctgcta tttgccgtca
     9841 attatcactg cgtgatgata tcgaattagt ggtcaaaaca cacaaagaac tcgatctaac
     9901 cgtacagaaa gatgttgatg cattttttga gcaagagaaa attgatcagg tttatcttgc
     9961 tgcggctaaa gttggtggta tttatgccaa caatacattt ccggcagaat tcatctatca
    10021 gaatctcatg attgagagca atattattca ttcagctcac aaggccggaa ttcaaaaatt
    10081 acttttttta ggctcaagct gtatttatcc taagtttgca gagcagccga tgaacgagtc
    10141 tgaactttta acgggcatac ttgagccaac taatgagcca tacgcaattg ctaaaattgc
    10201 gggtataaaa ttatgtgaat cttataaccg gcaatatggc cgtgattatc gcagtgtaat
    10261 gcctactaat ctttatggca taaatgataa ttttcatcct gaaaactctc atgttattcc
    10321 ggcactcatg cgtagattcc atgaagcaaa agagagtggt gcaccagagg ttgttgtttg
    10381 gggaaccgga acaccgatgc gtgagttttt atatgttgat gatatggctg ccgcatctgt
    10441 tcatgtaatg gaacttgatg aagcaattta tcaacaaaat actcagccta tgttatctca
    10501 tattaatgtt ggtacgggtg tggattgttc tatacgtgaa atggctgaaa caatggcctc
    10561 tgtggtgggt tatcaaggta aaattgtttt tgatgctacc aaacctgatg gcactccgcg
    10621 taaacttatg gacgttaccc ggctcaaaaa cctgggctgg caatatcgct ataatttgca
    10681 tgaaggctta tcattaacat ataaatggtt tattgagaat attaattctt ttcggggata
    10741 gttatgaaca agagattgga atgtgagtta tttaaaacaa tagttgagca tactcctcta
    10801 atctcgattg atctcataat tagaaacgat aaaggagagg cgctgcttgg gcagcgcctg
    10861 aatcgcccag cacaaaatta ttggtttgtg cctggagggc gaatttataa ggatgagtca
    10921 ttcgaggttg catttaatcg gataacattt gaagagttgg gcgttcaaat tagtcttaat
    10981 gacgccttat ttcttggggt gtatgaacat ttctacaatg ataatttttc tgaagcagaa
    11041 ttttctacac actatgtagt gcatggatat gaaatccaac ttaatcctca gcaacttcac
    11101 ctaccaacgg tccagcataa ttcctacaag tggtttgatg tagtaacgtt gcttaatagc
    11161 actatagttc atcaatatac caaaaattat tttataccaa ggtaatagat atgctacttc
    11221 ccgttgtcat ggccggtggt tctggtacca gattatggcc tctttcacgt acactttatc
    11281 cgaaacaatt tctgtcttta aatagtcgtt taaccatgtt gcaagagaca ttgcggcggc
    11341 ttgacaaggt cgaacataaa cccgctttgg tcatttgtaa cgaatcacat cgctttatcg
    11401 ttgctgaaca attgcgtaaa gagggtttaa agcatagcgg tattttgctt gagcctgttg
    11461 gtcgtaatac tgcgcctgct gtagcactcg cagcacttca ggctatggta actggagatg
    11521 accctattct gttggttctt gctgcagatc atgaaatcca ggatgaggat aatttcattg
    11581 ctgcagttct tgctgccaag aattttgcag agcagggtaa gcttgttaca tttggtattg
    11641 ttccaacatc cccagagact ggctatggtt acattaagtc aggtgaatct ctggatgaac
    11701 aaggttataa agttgcagct tttgttgaaa aaccagatct tcacgtggct cagcggtaca
    11761 tatcagaagg cggttatctt tggaatagtg ggatgtttat gttcagagcg tctgtattta
    11821 tcgatgaact gaaaaaattc cgaccagata ttttagccag ttgccaacgc tccctgtcct
    11881 cttcgataca agatttagat tttatccgcc tggataacgc ttcattttct tgctgtcctg
    11941 aagagtctat tgactatgcc gttatggaaa aaacagccga agctgtcgtc gttccattaa
    12001 atgcgcaatg gagtgatgtc gggtcatggt ctgcattgtg ggaaataagt tcaaaagacc
    12061 aaagcggcaa tgccattcgt ggtgatgtat tggttgaaga tgctacagat agttatcttt
    12121 attcgcagca tagacttatt ggtgccgtgg gcgtaaagga tttggttgtt gttgaaacga
    12181 aagatgcagt attagttgct cataaagata aagttcagca agttaaaaat atcgtcgctc
    12241 aactaaaaaa gaataatcga acagaatatt tacagcatcg ggaaatttat cgaccttggg
    12301 gcagtcatga tactatagct gaaggggaac gattccaggt aaagcatgtg attgtattac
    12361 ctggacatat tactgctaaa cagatccatt accatcgcac tgagcattgg gtagttgtat
    12421 cggggacagc taaagttcat cttgaggata agacttacct tgtctctgaa aatgaatcaa
    12481 catatatacc tgttggtgtt ccacatgcta ttgaaaatcc tggcaagatc ccgctcgaaa
    12541 taattgaggt tagatcggga gtctatctgg aagaggatga tgttataaga gtttcttctt
    12601 ctggagtcgg atactaatga gaatttcgat tattacagcc acttataata gtgaaaaaac
    12661 cctccttgat acattacttt ctctagaaaa gcaaacacat ccagatatcg aatatatagt
    12721 tatagatgga gcatcaaaag ataatacaat caaactaatc aaaagtaatt gtacaagagt
    12781 ttcaaaaatc atttgcgaac ccgataatgg catttatgat gcgctaaata aaggaattca
    12841 agccgcttcg ggtgatgtca ttggtttttt acattctgat gacttacttg cttatgatga
    12901 tgttattgca gatatagcaa aaacatttga aagttcagga tgtgatgctg tttatggcga
    12961 tttggagtat gttgcccaaa atgatacgac taaacgtatt agattatgga aaagtggctc
    13021 attcagtcgt ttgaagatga aactgggttg gatgccgcca cacccatcat tttatatgaa
    13081 acgtgattgt tatggtcagt ttggttgttt ttcattagat tatcgaatat ctgctgatta
    13141 tgattcattg ttacgttata ttttaaaaca acgcatttca atagcgtatt taccgcaagt
    13201 attagtgaag atgcgtgttg gtggaattag caatcgttca ttatcttcca tggtcaacaa
    13261 gtcgatggag gatattcgtg ttatgaaaca gaatggtatt ttctggccaa tagctttagc
    13321 gtataaaaat ctatccaaac ttcctcaatt cattaaaaag taattatcat gttaaatgct
    13381 aaaaaaatca ttaccgatag caatattgct ttcggaacta gtggggcgcg tggtctcgtt
    13441 gtcgatttta cccatgatgt ttgtgctgcg ttcactcatg cgtttctttc tgttattgat
    13501 gataaataca atcttaataa agttgcctta gcaattgata accggccaag cagttacgaa
    13561 attgctcagg catgcgcctt agctatcaaa caacatgggt tcactgtcga atatcatggt
    13621 gtaattccta ctcctgcatt agctcattat tctatgcaga aaaacattcc ctgtataatg
    13681 gtcactggga gccatatacc ttttgatcgt aatggtttga aattctacag accagatggc
    13741 gaaatcacaa aagaggatga actagcaata gtaaatagtg aatatgtctt ttctcctgta
    13801 gatgtattac ctcatcttga actaagcact caaggagcgg attgctatct taaacgttat
    13861 gtttctcttt ttaattccga tattttgaaa ggaaaaaaaa tagggatata tgaacattct
    13921 agtgcaggac gagatttata tgctcctctt tttaatcaat tgggcgctga ggtcatttcc
    13981 cttggcagaa gtgatgaatt cgtccctatt gacactgaag cagtaagtga tgaagatcgt
    14041 atacttgcaa gagagtggtc taaaaaatat aatcttgatg ctattttctc tacagatggc
    14101 gatggtgatc gtcccttagt tgccgatgaa aatggtgaat ggctaagagg cgatattctg
    14161 ggattactta ctgctattga acttaatatc aaggcgttgg ctattccagt cagttgtaat
    14221 actgcaattg aacaatctaa caaatttgca agtgtacaac ggacgaaaat aggctctcct
    14281 tatgtgattg cagcgtttgc ggatcttgct aagcaatttg attcagtcgc tggttttgaa
    14341 gctaatggtg gttttctgct tgcctccgat ttacaaataa atggcaagga attaaattca
    14401 ttacctacac gagatgctgt gttaccagca ttaatgctct taatagcttc acgcaacagt
    14461 accatctctc aactggttaa taatcttcca cagcgattca cttggtcaga tagggttaaa
    14521 gatgtccctt cagagtcaag tcaacatatt ataaaaaatg ccatattgtc acccaataat
    14581 ttctttaata gcttaggata tgaatcatta tcctgttccg ctattgatga aacggatggt
    14641 gcaagattta ctttaaataa tggtgatatt atacacctcc gtccttccgg taatgcccca
    14701 gaactccgtt gttatgctga agccagtaat gaaaatcagg ctaagcaata tgttacgaaa
    14761 gtccttggaa acattacctc tttgatttct tgatgttata gatttatcta cgtttatatg
    14821 cgtgcgtagg tttggttaca agtagatgcc gatataaagg aagattaacg atattcgttg
    14881 tattagtact acacacattc gtgcaacttg agataacatc tcaatcatat tcaagtcgcg
    14941 catacatcgc gctgaacacc ccctgacagg agtaaacaat gtcaaagcaa cagatcggcg
    15001 tcgtcggtat ggcagtgatg gggcgcaacc ttgcgctgaa catcgaaagc cgtggttata
    15061 ccgtctctat tttcaaccgt tcccgtgaaa aaacggaaga agtgattgcc gagaacccag
    15121 gcaagaaact ggttccttac tacacggtga aagagtttgt tgaatctctg gaaacgcctc
    15181 gtcgcatcct gttaatggtg aaagcaggtg caggcacgga tgctgctatt gattccctga
    15241 aaccatacct cgataaaggt gacatcatca ttgatggtgg taataccttc ttccaggaca
    15301 ccattcgtcg taaccgtgag ctttctgcag aaggctttaa cttcatcggt accggtgttt
    15361 ccggtggtga agaaggcgcg ctgaaaggtc cttcaatcat gcctggcggc cagaaagaag
    15421 cctatgaact ggttgccccg atcctgacta aaatcgccgc tgtggccgaa gatggcgaac
    15481 cgtgcgtaac ctatattggt gccgatggcg caggccatta tgtgaagatg gttcacaacg
    15541 gtattgaata cggagatatg caactcattg ctgaagccta ttctctgctt aaaggtggcc
    15601 tgaacctctc caatgaagaa ctggcgcaga cctttaccga gtggaataac ggtgaactga
    15661 gcagctacct aatcgacatt accaaagaca tcttcactaa aaaagatgaa gacggtaact
    15721 acctggttga tgtgattctg gatgaagcgg ctaacaaagg taccggtaaa tggaccagcc
    15781 agagcgcgct ggatctcggt gaaccgctgt cgctgattac cgagtctgtg tttgctcgtt
    15841 atatctcttc tctgaaagag cagcgcgttg ccgcgtctaa agttctctct ggcccgaaag
    15901 cacagccagc aggcgacaag actgaattca tcgaaaaagt tcgtcgtgcg ctgtatctgg
    15961 gcaaaatcgt ttcttacgct cagggcttct ctcagctgcg tgctgcgtct gaagagtaca
    16021 actgggatct gaattacggc gaaatcgcga agattttccg tgctggttgc atcatccgtg
    16081 cgcagttcct gcagaaaatc actgatgcat atgccgaaaa tccgcagatc gctaacctgc
    16141 tgctggctcc gtactttaaa caaatcgccg atgactacca gcaggcgctg cgcgatgtcg
    16201 tcgcttatgc agtacagaac ggtatcccgg ttccgacctt cgccgctgcg gttgcctatt
    16261 acgacagcta ccgtgctgca gtactgcctg caaacctgat ccaggcacag cgtgactatt
    16321 tcggtgcgca tacttataag cgcattgata aagaaggtgt gttccatacc gaatggctgg
    16381 attaatctga tttaaatcaa ttaatcaatg caaggcccgg agaaaccctc cgggcttttt
    16441 tattatacaa agcggcaggt tatggccttt ttttataatt tatgattaaa aaagcgatat
    16501 aatacatagc cgcacagcaa gaacgctgcc ttgacagttc atccgcatca gcgttaaaaa
    16561 tcccgcagta gatgaagttg tggtggtgga ttaatgacca ctctaaatgt ttaaccggaa
    16621 gaagtcagag ctaatgaaaa taacaatttc aggaacaggt tatgttggtc tttcaaatgg
    16681 tattctgatt gcgcaaaacc acgaagtggt tgcactggat atcgttcagg ccaaagtgga
    16741 catgcttaac aagaagcagt caccgattgt tgataaggag attgaagagt atctggcgac
    16801 taaagatctc aatttccgcg ctacaacaga taagtatgac gcgtataaaa atgccgatta
    16861 cgttattatt gccacaccta ccgattatga tccgaaaaca aattatttta atacctcaag
    16921 cgtggaagcg gtcattcgtg atgtgacaga aattaatccc aacgctgtaa tggtgattaa
    16981 atctacaatt ccggtaggct ttaccaagtc aattaaagaa cgtctgggta tcgataacct
    17041 tattttctcc cccgaattcc ttcgtgaagg taaagccctt tacgataatc tccatccttc
    17101 gcgtattgtc atcggcgagc gttcagaacg agcagaacgt tttgctgcgt tattacagga
    17161 aggggcaatt aagcaaaata tttcaaccct gtttaccgat tcaaccgaag cagaagcgat
    17221 caaactgttt gctaatacct atctggccat gcgcgtggcg tactttaacg aactggatag
    17281 ctatgcggaa agtttaggtc tgaatacccg tcagattatc gaaggtgttt gccttgatcc
    17341 gcgtattggc aaccattaca acaacccgtc ttttggctat ggcggttatt gcctgccgaa
    17401 agacactaag cagttactgg cgaactacca gtctgtgccg aataacctga tatcggcaat
    17461 tgttgatgct aaccgcacgc gtaaagactt tattgccgat gccattttgt cacgcaaacc
    17521 gcaagtggtg ggtatttatc gtctgattat gaagagcggt tcagataact tccgtgcgtc
    17581 ttctattcag gggattatga agcgtatcaa ggcgaagggc gtagaagtga tcatctacga
    17641 accggtgatg aaagaagact ctttcttcaa ttctcgcctg gaacgtgatc tcgccacctt
    17701 caaacaacaa gccgatgtca ttatctccaa tcgaatggca gaagaactaa aggatgtggc
    17761 agacaaggtc tacacccgag atctcttcgg cagcgactaa ccttctgtaa tcagggcgat
    17821 ttttgccctg attgtctttt gttacccgcg caataatcta ttatttttat catttatcct
    17881 atagcattca ctatgattat agttacacta tgcggaccta aaattttacg tcagttaggg
    17941 taatgatgag agtagaaaat aataatgttt ctgggcaaaa ccatgacccg gaacaaattg
    18001 atttgattga tttactggtg cagttgtggc gtggcaagat gacaatcatc attactgtca
    18061 ttgtggctat tgccctggct atagggtatt tggccgttgc caaagaaaaa tggacttcct
    18121 cagctatcgt tactcaaccg gatgtggggc aaatcgcggg ttataacaat gccataaatg
    18181 tgatttatgg ttcggcagcg ccgaaagtgt ctgagatcca gtcgatgtta attggtcgtt
    18241 tcagcacgac attttctgca ttagcagaga cgctggataa tcaggaacaa gcagaaaagc
    18301 tgactatcga accttcagtt aaaaatcagc cattgccact ggcagtgtct tatgttggtg
    18361 aaacgcctga aggtgcgcag aagcaactgg cgaagtatat ccagcaagtt gacgaccagg
    18421 taaatgaaga actggaaaaa gacctgaaag acaacatcgc gctgcgaatg aaaaacttgc
    18481 aggattcttt gaaaactcag gaagtggtgg cgcaagagca gaaagatctg cgtatccgcc
    18541 agattcagga agcgttgcag tatgcgaatc aggctcaggt ctcgaaaccg cagattcagc
    18601 agactcaaga tgtgacgcaa gatactatgt tcttgctggg gagcgaagcg ctggagtcga
    18661 tgattaagca cgaagcgacc cgtccattgg tgttttcgcc aaactactac cagactcgtc
    18721 aaaacctgct ggatattgaa agcttaaaag ttgatgatct tgatatccat tcttaccgct
    18781 atgtgatgaa accgacatta cctattcgtc gcgatagccc gaaaaaggca attaccttga
    18841 ttctggcggt gctgctgggt ggcatggtag gcgcggggat tgtgttgggg cgtaacgcac
    18901 tgcgtaatta caacgcgaag taatcttttt ggttttaaag aaaacgggca gggtggtgac
    18961 actttgcccg ttttttttgc cggatgcgac aacaacatcg catccgctta ccccgccact
    19021 cactgatgcc gtttgcgcag attctcaatt acggttgtta aatccagatc ctgatcctgc
    19081 aacagcacca gcaggtgata catcaagtcc gatgcctcat tggtcagttc gaagcggtca
    19141 tgtaccgtcg cggccagtgc ggtttccacg ccttcttcac ccactttctg cgcaatgcgc
    19201 ttggtgccgc tggcatacag cttggcggtg taggaggttt gcggatcggc agatttgcgt
    19261 tcagcgagca gttgttccag ttgatacagg aacagccact ggtgagcggt gtcgccgaag
    19321 cagctgctgg tgcctttgtg gcaggttggg ccaacaggat tcgccagtac cagcagggtg
    19381 tcgttgtcgc agtccggcgc aatactcacc acgttgagga aattgccgga cgtttcgcct
    19441 ttggtccaca gtcgctgttt agtacgcgag aagaaagtga ctttgccgct ttcgagggtt
    19501 ttgtctaacg cttccgggtt catatagccc agcattagca cttcgccgga taccgcgtgt
    19561 tgcacaatca ccggcatcag tccgtcggtt ttttcccagt ccagttcgcg gcgttgttgt
    19621 tctgttaaca tatcctgatc tccacgccct gtgttgccag gtacgctttt aattcaccaa
    19681 tattgattat ttgtttgtgg aatacggaag ccgccagcgc gccgtcaacg tcggcatcac
    19741 ggaaggcttc gaggaagtgt tccatggtgc ccgcgccacc ggaggcaatc agcgggacgc
    19801 ggcaaacttc tcgcactttt ttcagctgct cgaggtcgta accgttacgc acgccgtcct
    19861 gattcatcat gttgaggacg atttctccgg caccgcgttt ttgcacttcc tgtacccagt
    19921 cgagtgtttc ccact
//