<pre>LOCUS       KJ755554               11239 bp    DNA     linear   BCT 29-MAR-2016
DEFINITION  Escherichia coli strain H 510c serotype O37:K-:H10 O-antigen gene
            cluster, complete sequence.
ACCESSION   KJ755554
VERSION     KJ755554.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11239)
  AUTHORS   DebRoy,C., Fratamico,P.M., Yan,X., Baranzoni,G., Liu,Y.,
            Needleman,D.S., Tebbs,R., O'Connell,C.D., Allred,A., Swimley,M.,
            Mwangi,M., Kapur,V., Raygoza Garay,J.A., Roberts,E.L. and Katani,R.
  TITLE     Comparison of O-Antigen Gene Clusters of All O-Serogroups of
            Escherichia coli and Proposal for Adopting a New Nomenclature for
            O-Typing
  JOURNAL   PLoS ONE 11 (1), E0147434 (2016)
   PUBMED   26824864
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11239)
  AUTHORS   Yan,X., Fratamico,P.M., Tebbs,R.S., O'Connell,C.D., Baranzoni,G.M.,
            Liu,Y. and Debroy,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-APR-2014) Molecular Characterization of Foodborne
            Pathogens Research Unit, USDA-ARS, 600 East Mermaid Lane, Wyndmoor,
            PA 19038, USA
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: CLC Genomics Workbench v. 7.0
            Coverage              :: >50X
            Sequencing Technology :: IonTorrent
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..11239
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="H 510c"
                     /serotype="O37:K-:H10"
                     /db_xref="taxon:562"
     misc_feature    1..11239
                     /note="O-antigen gene cluster"
     gene            3268..4323
                     /gene="galE"
     CDS             3268..4323
                     /gene="galE"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="AIG62503.1"
                     /translation="MSILVTGGCGYIGIHTIFTLITQGHSVVVLDNLTNSSIEPLKRV
                     ELMANCNIPFYKGNVGDKRLLVEVFNKHQITAVIHFAGLKSVSESMKKPIEYYSNNVT
                     QTLSLLESMIDNNIKSFIFSSSATVYGKPNECPIKESHKIGNTTNPYGTSKFIMELML
                     SDLCEAYNDLNITILRYFNPIGAHESGNIGEHPNGVPNNLFPYLMKVAIGEYPYLNVY
                     GNDYSTYDGSGIRDYIHVVDLAEAHAKALSKNLVVDGLKIYNLGTGKGYSVFEVIETF
                     EKITGIKIPYRVMPRRDGDVAECWSNSLKANEELEWKATKDLSDMVRDAWNWQLKNPH
                     GYDNDEVMLLDSKMDDL"
     gene            4784..5239
                     /gene="tagD"
     CDS             4784..5239
                     /gene="tagD"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="AIG62502.1"
                     /translation="MKTIETRNVKFIKFIRLLGCIMKKVITFGTFDVFHVGHINILER
                     ASKLGDYLIVGVSSDKLNFSKKNRFPIYSEKDRVKIISSLRFVNEVFIEESLELKLEY
                     IKKYNVDLLVMGDDWAGKFDWVKSNCEVIYLPRTPSISTTEIIEIVRSI"
     gene            5241..6473
                     /gene="wzx"
     CDS             5241..6473
                     /gene="wzx"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="AIG62501.1"
                     /translation="MFRRIISHRVFKNSFALFIMQLFSYVSPLLVLPYLARIMSVENF
                     GMLMMLYSLLAICLVVTDFGFNLSGTYYISRNYKNKKKINEFLTSVFCIKIILSTASV
                     IFFLVFFRGEFQRLDKYSVLLIAITMFVQSFQPIWFFQGIEKMRHITIYTALSKLIYL
                     LLVFLFVTSDSIVTVLLCYCISQMVGTFFSICFILKMKYSFSRTTYKNIISVFRQSIP
                     FFVSRVAVVVYTSANTLFLGKYGGMAQAASYSSCEKIYFAGQSLLNPLSQAFFPYLSK
                     NRDAKFYIKFVILSVCILSVICAVASFFVYDFLNIFYGQKYNDSIGILNTFLITTVIA
                     YTSVSFGYPMYTLIDKIGYVNHTVIIGAVIHIIGLFILAKENIFTAQNIAYLVLIVET
                     SVLITRVFLYTYLKIKRV"
     CDS             6473..7201
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AIG62500.1"
                     /translation="MELFNLINYSLYNSIIGRSYRKILRVFERNKNINKAQYGEMVVN
                     DVMKLNYNYFPMFGTLLSLHRDGRFVFADDFDFAIIGDFPEDIISTFERNGYQLCALS
                     LIGNKREIIEYSFSKKIKNEYIKVDIFKLKEVNNIIRHSCPNFRKEKEFVRFRDGLKI
                     CQFNSYFTVDYPKFDLTVSKWGIKIPNNPDDIFELHYGHDWEIPKTSNFIDFSAYRFI
                     AERSETVLGPSEKLKEYIKNNMSC"
     gene            7204..8337
                     /gene="wzy"
     CDS             7204..8337
                     /gene="wzy"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="AIG62499.1"
                     /translation="MIRLQNIILFVLLAFSGVYVSSWLIKPSYVAVIISFFILTILTL
                     RGVRYSFSSSIFILIAICVFYTIFNQFALEGELPTIIFYSCLILIPLLVSTFKSSTSK
                     SNILLVSYIILIIYYSFETFIRITNPDYSHLPKTGDDGITSTFYIYKINSIAFEDSNF
                     ISVILVVYYISLRSTALYSDIKVKYSLGLNIGLLTLILLTFSRSAYIGVLIFECMVLF
                     FFKPDVNMKLRGLLVSIILVGGGICAHFIIEKIASDPSFISKFYIVDLTVKYLSHAST
                     LDILFGIGFGNAINVLGMGAHNIFIAIFIENGLIGTLLYLYILIMLSIRYKLTMLLII
                     PISIMGLSFSQIAMPYFYVVIAWLIFVNEDRCEKISKCCNAHL"
     gene            8300..9214
                     /gene="epsE"
     CDS             8300..9214
                     /gene="epsE"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase 2 family protein"
                     /protein_id="AIG62498.1"
                     /translation="MKKLVSVVMPTYNNEKYIKSAIDDIMNQTYQYWELIIINDGSTD
                     NTCQILSEYNKVNNIHIINLVANKGICEALNVGLKIAKGDFILRFDADDRCSSDRISK
                     LLEYMLKNNIDIVGSSVITINENDDVIGKAVFSDNERIISRLIRYENPILHIWLAKRE
                     VYDKLGGYRIGGVEDYDFILRALDSGYKVSNISDYFGISIRKHSRNTANTQGWRQRKC
                     FNLAWTLHKERLKKGYEVTSSIPRYGRFIKYGDKIHAISNKLLVKGISSKKLSYKIAI
                     IVAAAVISPYQFQYLIYRFIGKIIKKTL"
     gene            9211..10278
                     /gene="gtf1"
     CDS             9211..10278
                     /gene="gtf1"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="AIG62497.1"
                     /translation="MKILYIIPSLKKCGPVNVCLSLAKNISENHSVSILAFRNGNSFN
                     DFYSCCDNVKIIPIYNLFAIARFIAAEKFQIIHSHCLVPDFLLSLFSFFFRNKFIPIS
                     TIHNYIDIDYIFSKGLFIGKLMGVINRLSLSKIKNLVSCSLAVKYYCDVAYDIRSTAI
                     SNGVPISPYIDEMQQECNKKFIDFYYVGVLTERKNVDLLIQSFHLYKRKYKNEDRLHV
                     IGGGELLEVLKKNNKCDYIIFYGPQVNPWPIIKSLDIYVSSSRAEGMPLALLEALSIG
                     KAYICSNIEPHCEVHHVVNGGIICSFDKDDFVKAFHHMRYWDLKPKNEYILERFKNNY
                     ADYIMAGKYLIKYEELLKEHE"
     gene            10271..11086
                     /gene="wbbD"
     CDS             10271..11086
                     /gene="wbbD"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol
                     beta-1,3-galactosyltransferase"
                     /protein_id="AIG62506.1"
                     /translation="MNDIRFSVLMSLYKNESEKFLDDCFSSVYDQTLPANEITLVIDG
                     PIPNSLEYVVLKWMVFLPINVVRLEKNVGLGQALNYGIKACSNDIIIRMDTDDICKRN
                     RFEVLVKKLNSNNRLAVVGSCIEEFVHLPSNIISVRTVPLDPESIRKEILVRNPFNHM
                     SVAFRKKFIESVGGYVHHHFMEDYNLWLRVVASGFDVCNINESLILARVGDNMLARRK
                     GLRYIKSEFQLYRLKVKLGLQSHISGFCILLVRSIPRLLPLKVLKIIYQYIRK"
ORIGIN      
        1 tctggtagct gtaaagccag gggcggtagc gttcagtgaa atattacgtg atgctgcagt
       61 gtacttaata attcgtaaac tatgttcaag gattgatgcg tcccttatcg tctaaatcgt
      121 ctttcacaac ttatatatgg ttgaatacct attatataaa taagttagag aattgatgga
      181 catatttctt ttatcccccg attaaagaca agcctaggaa gtagaacata tattgtctga
      241 tattctactg ttgactattt gcaccgttat tttggtacag aaggttggga agatatagag
      301 gattttggga aaacacctct cgattttttg aagcaatatg gtgattttga aaatggtatt
      361 cctgttcacg ataccattgc tagagttgta tcctgtatca gtcctgcaaa atttcgcgaa
      421 tgctttatta actggatgcg tgactgtcat tcatcagatg ataaagatgt catcgcaatt
      481 gattgaaaaa cactccgcta ttcttatggt aagagtcgcc gcaggggagc gattcatgtc
      541 attggtgtgt tctcaacaat gcacagtctg gtcatcggac agatcaaggc ggataagaaa
      601 tccaatgaga gtgtgccgtg ggggttgaaa ctagcctgct tggataacag tcagtggtga
      661 acataagctt gtgaagagaa ggaggtcggc cttccagagt cgatggtcgg aggttgactc
      721 taaaccccct tcaggtggct gtcattaaga gtgatggtca gaagcgttga agggaaatca
      781 gaataagatt ctggcgaggt aagatgtaag gagaggagta accccgaacc tgtgttgaca
      841 cgtcgttatc tttaaaatgg catcggaact gaggtcgtct cgttatctct ggataagcac
      901 actggcgaag tccgaatgtt gagtgtgcgg tgtccggcgt aaagcaggca tgaccttata
      961 tcaggctctt tgtagtaacc acgggaacca gtcatcatga tgttaaggaa gaaaggtaaa
     1021 tcaccgaaat gataagcctg tgagtaccga agcatgatac tggggcggag caacttgtag
     1081 cagtgaggaa gcatttgtaa tgagtgtgga acgaagggag ggcgttaagc agtctgaacc
     1141 ggcatctcaa ctgtcacaat gtggcaggag gaaggcgtgc gggcaggcaa aaccatttgc
     1201 gatctaaaaa tgggaagtgc aggccgcgtt tgataaagtg aaagcgaatc aaggcggggc
     1261 gggtattgat ggtgtaacgc ttgagatgtt tgaaagaaat cttaataaca acctgtataa
     1321 gatatggaat cgtctatcat ttgaaacgta ttttgctccg tcagtaaaag cggtcaatat
     1381 accgaagaaa acaggtggag taagagcgtt aggtattccg acggttgtga tcgggtagcg
     1441 cagatggtga ttaaagagcg acttgaggca ataatagaac cctgttttct gagtgattcc
     1501 tatggttaca gatcggcaaa atcagcgatt caggctattg gtgtaacaag aaaacgctgt
     1561 tgggaatata attggattct gtagtttgat atcaaaggtc tgtttgataa tatacggcat
     1621 gatttactgc ttaaagcagt tgaaaaacat gttgctaatg gttctcaaat tcaagggcaa
     1681 gagctgagtt tgctcacctt ctatataaaa cgatggttag tttcaccatt gcagcaggat
     1741 gacgggaata ttatcttgcg agattgggga caccacaagg gggcttagtc agctcacttc
     1801 tggcgaattt attttcacac tatgtttttg ataaatggat gcagagagaa tttcccgaaa
     1861 atccgtggtg tcgatatgca gatgatggac tggttcatgc tatcactaaa ggcaaagcag
     1921 aatcactgta tgaaaggata aaacgccgtt tggaagagtg tggtctcgaa ttacatccag
     1981 aaaagacgaa aataatatat tgtaaggacg ataaaagaaa gtgaacatgt gttcacacta
     2041 gcttcgattt tatgggatat acattcagac aaagaagatg taggaaatgc tcacataata
     2101 cattcttcaa tagctttatt ccggcagtgg gtatgatgaa gaaatgagac ggaggagcag
     2161 ggagctgaaa atcaggcaaa agagccacta tagtttagaa gaactatcac gttggttaaa
     2221 cccaatagtg cagggatgga taagctatta tggtcaatat tgtcggtcgg ttctcgatcc
     2281 tgtatttcga catatcaata aaacgctggt gcgttgggca agaaggaaat tcaagacgct
     2341 aaagaggcac aaaagtagaa cgataggtct gtttgacaga ttatcggtaa agtcttccaa
     2401 actattcgct cactggcgat ttggctcagt aagaacgttt gcttaatgga agcggaatga
     2461 attgagaggt tcacgttcca ttttgcgaga ggctagaggg gaagttcctc cggtctactc
     2521 acctcacagc tatttaagag cttcttaaca tattggggat taaagaaaaa attatcacaa
     2581 ctgatgcgat ggggtgccag aaagatattg cagagaaggt acaaaacagg gaggtgatta
     2641 tttattcgct gtaaaagaaa atcaggggca gcttaataaa gcctcgagga aaagtttcag
     2701 ctgaaagact tgaatgatcc aaagcatgac agttacgcaa ttagtgaaaa gagtcacggc
     2761 agagaaaaaa tccgtcttca cattgtttgc gatgtccctg atgaacttat tgatttcacg
     2821 tttgaatgga aaggactgaa aaaattatgc gtggcagtct cctttcggtc aataatagca
     2881 gaacaaaaga aagagccaga aatggcggtc ggatattata tcagttctcc tgatttaccg
     2941 cagagaagtt cgccacagcg attcgaaatt actggcacca gaaagtgata atgagtgaag
     3001 atgaccgcaa aataagaaga ggaaacgaag cggaattatt tttagggata cggcgcatct
     3061 ctattaatat tttgacgaat gaaaagatat tcaaggcagg gctaagacgt aagacacgaa
     3121 aagcagtcat ggacagaaac tatctagcgt cagtccttgt gggtaacggg atttcgtaat
     3181 cttgttctga ctgctataaa gaccttatga gttcttaaaa agcatttttt gccaagagta
     3241 aattattgac tatcgattgg agagtgtatg tctattttgg ttactggtgg gtgtggatat
     3301 attggaatcc acacgatttt tactctgatt acccaaggtc atagtgttgt tgtattagat
     3361 aacttaacta actcatctat agaaccattg aagagagttg agttgatggc aaattgtaat
     3421 atacctttct acaaaggaaa tgttggggat aaaaggctat tagtagaagt atttaataag
     3481 catcagatta ctgctgtaat tcattttgca ggattgaaat cagtaagtga atctatgaaa
     3541 aaaccaattg aatattattc taacaatgtt acacaaacat tatctctgtt agagtcgatg
     3601 atagataata atatcaaaag ttttatcttt agttcctctg ctactgtata tggtaaacca
     3661 aatgaatgtc ctataaaaga atcacataaa attggtaata cgacaaatcc ttatggaact
     3721 tcaaagttta taatggaatt aatgttgtca gatttgtgtg aggcatataa tgatctaaat
     3781 ataactattt tacgatattt taatccaata ggtgctcatg agtcaggtaa tataggtgaa
     3841 catccaaatg gggttccaaa taatcttttt ccttatctca tgaaggtagc tataggagag
     3901 tatccatatt taaatgtgta tggaaatgat tactcaacat atgatggttc tggtatacgt
     3961 gattatatcc atgtcgtgga tcttgcagaa gctcatgcca aagcattatc aaaaaattta
     4021 gtggtagatg gtttaaaaat ttataactta ggaacaggga aaggttattc tgtatttgaa
     4081 gttatagaaa cttttgaaaa aataacaggg ataaagattc catatagagt tatgccccgg
     4141 agagatgggg acgtcgcaga atgttggtca aatagtttga aggcaaatga agaattagaa
     4201 tggaaagcaa caaaagattt atctgatatg gtaagagatg cttggaattg gcaattgaaa
     4261 aatcctcatg gttatgacaa cgatgaagta atgctcttag atagtaaaat ggatgatttg
     4321 taaatgcgat ttaagtttag tactatgagg tgtgggggag aggggatgac tgatgttctt
     4381 tattagaaaa atttacttat cagtggtcag tttttctgta taaagagttt atacagagtg
     4441 agtaattttt gattggttta tcgacgcggg gtataacagt ataagtttcg cgtctattta
     4501 tattcggatt atattcatac tgaagccaga ttttatagag gagttattga taaatttcta
     4561 ttgatagttg aatatataaa tacaatgttg atatggggtt atgtttatta tatttggatg
     4621 agaagcaggg gcattgtaag tgaatcttag gcaagaataa tatacagtat gatcatatca
     4681 tcagcttgtt gaaaaataca tgatttatca gtacataaaa atatatcttg taacttttat
     4741 tgattaaaat ggaaaggcaa atttataata tgctagttag gtagtgaaga caattgaaac
     4801 aagaaacgtt aaatttataa agtttattcg attattagga tgcataatga aaaaagtaat
     4861 aacttttggt acatttgatg tatttcacgt tggacatata aatattttag agcgagcgtc
     4921 taaactcgga gattatttga tcgttggagt atcttccgac aaacttaact ttagtaaaaa
     4981 aaatcgtttt ccaatttata gtgagaagga cagggtaaaa ataatttcat ctttaaggtt
     5041 tgttaatgag gtttttattg aggaatcgtt agaacttaaa ctggagtata ttaaaaaata
     5101 taatgtagac ctgctggtta tgggagatga ctgggctgga aaattcgatt gggttaaatc
     5161 aaactgtgaa gttatttatt tgcctagaac accatctatt tcaacaacag aaattattga
     5221 gatagtaagg tctatttgaa atgtttagga ggataatttc acatagggtg tttaagaatt
     5281 catttgcatt atttatcatg cagttatttt catatgtttc accattattg gttcttccat
     5341 atctggctag gatcatgtct gtagaaaact ttggcatgct aatgatgctg tattctttat
     5401 tagccatatg ccttgtcgtg actgattttg gttttaattt atcaggaact tactatatat
     5461 caagaaatta taaaaataaa aaaaagataa atgagttttt aacatctgtt ttttgcatta
     5521 aaataatatt atctactgca tcagtaatat tttttctggt tttttttagg ggggagtttc
     5581 aacgtttgga taaatactcc gtgcttttaa ttgcaattac aatgtttgtt cagtcttttc
     5641 aacctatatg gttcttccag ggtatagaaa agatgaggca tataactata tatacggcac
     5701 tgtcaaaact gatttatctt ttattagtgt ttttgttcgt taccagcgat tcaattgtca
     5761 cggtattact atgctactgt ataagtcaaa tggtaggaac ttttttttca atttgtttta
     5821 ttttgaaaat gaaatattcg ttttctcgaa ccacatataa aaatataatt tctgttttca
     5881 gacaaagtat tccttttttt gtgtcaagag ttgctgtggt tgtttataca tctgcaaata
     5941 cactttttct tgggaaatat gggggtatgg cgcaggctgc tagttatagc agttgcgaaa
     6001 aaatatattt tgcagggcaa agtttgttaa acccgttatc acaggcattt ttcccttatt
     6061 tgtctaaaaa tagagatgca aaattttaca ttaaatttgt aatattgtcg gtttgtattt
     6121 tgtcagttat ttgtgcagtg gcatcttttt ttgtttatga ttttttgaat attttttatg
     6181 gccaaaaata caatgattca attggcatat taaatacatt tctcataaca actgttattg
     6241 cttatacgtc agtcagtttt ggatatccta tgtataccct tattgataaa ataggatatg
     6301 taaatcacac tgtaattatc ggagcagtga tacatatcat aggactattt atattagcaa
     6361 aggaaaatat atttacagct caaaatattg cttatttagt tttaatagta gaaacatcag
     6421 tgctaattac aagagttttt ctttatacat atctaaagat taagagggtg taatggaatt
     6481 atttaattta atcaattatt cgctgtataa tagtattatt ggtcgaagtt atagaaaaat
     6541 ccttagggta tttgaaagaa ataaaaacat taataaggca cagtatgggg aaatggttgt
     6601 taatgacgtg atgaaattga actataatta ttttcctatg tttggtacgt tattatcgtt
     6661 gcatagagat gggaggtttg tatttgccga tgatttcgat tttgcaatta ttggcgattt
     6721 tccagaggat attatttcaa cctttgaaag aaatggttat caattatgcg ctttatcttt
     6781 gataggaaac aaacgtgaaa ttattgagta ttcttttagt aaaaagataa aaaatgaata
     6841 tataaaggtt gatatcttta aattaaaaga ggtgaataat attatacgac atagttgtcc
     6901 taattttaga aaagaaaagg agtttgtgag atttcgagat ggtcttaaaa tatgccagtt
     6961 caatagttat tttactgttg attatcctaa gttcgattta actgtcagca aatgggggat
     7021 aaaaatacca aataatcctg atgatatatt tgaacttcat tatggtcatg attgggaaat
     7081 acctaaaaca tcaaacttta ttgattttag tgcgtatcgc tttattgcag aaagatcgga
     7141 aactgtactc ggaccaagtg agaaacttaa agaatatatt aaaaataata tgagttgttg
     7201 atgatgatta gattgcaaaa tattatttta tttgtattac tagcattttc tggagtttat
     7261 gtatcatctt ggttgattaa acctagttat gtcgcagtta tcatttcatt ttttatctta
     7321 acgatattaa ctttacgtgg tgttaggtat tcgttttcat catctatttt tatcttgata
     7381 gcaatttgcg tattttatac aatatttaat caattcgccc ttgaaggaga attgccaaca
     7441 attatttttt actcatgcct gatattaatt ccattgcttg tatcaacatt taagagttca
     7501 acatccaaaa gtaacatact tctagtttca tacataatat taataatata ttactctttt
     7561 gaaactttca taaggattac taacccagat tatagtcatt tgcctaaaac aggtgatgat
     7621 ggtataacgt caacattcta tatttataaa attaatagta ttgcttttga agattctaac
     7681 tttatcagtg ttattcttgt ggtttattat atttcattaa ggagtacggc tctttatagc
     7741 gatattaaag ttaaatatag tttgggacta aatattggtc tgctaacttt gattttatta
     7801 accttctcaa gatctgcata tataggtgtg cttatttttg aatgcatggt tttattcttt
     7861 tttaagcctg atgttaatat gaaattacgt gggttgttag tatcaataat attggtaggt
     7921 ggtggtatat gtgctcattt cattattgag aagattgctt ctgatccgag ttttataagt
     7981 aaattttata ttgttgatct tactgtaaag tatttaagtc atgcgtcaac tttagacatt
     8041 ttatttggta taggattcgg caatgctatc aatgttcttg gaatgggagc gcataatata
     8101 ttcatagcga ttttcataga aaatggcttg ataggaacat tattatactt atacatatta
     8161 attatgcttt caatacggta taagttaact atgttattaa ttattccaat tagtatcatg
     8221 gggttatctt tttcgcaaat agcaatgccg tatttttatg tagttattgc atggctgatt
     8281 tttgtaaatg aggacagatg tgaaaaaatt agtaagtgtt gtaatgccca cttataataa
     8341 tgagaaatat attaagtctg caatagatga tattatgaat caaacttatc agtattggga
     8401 gttaataata attaatgatg gttcaacaga taacacctgc caaattttat cagaatacaa
     8461 caaggttaat aatatacata ttattaacct tgttgctaat aaaggaattt gtgaagcatt
     8521 aaatgttggt ttaaagattg ctaagggaga ttttatcctc aggtttgacg cagatgatag
     8581 atgttctagt gatagaataa gtaaattact tgaatacatg ttaaagaata atattgatat
     8641 agtaggaagc tctgtaatta ctataaacga aaatgatgat gtaattggta aagccgtttt
     8701 tagtgataac gagaggatta taagccgttt aataagatat gaaaacccta tattacacat
     8761 ttggctggca aaaagagaag tatatgataa attaggaggg tataggatag gaggagtgga
     8821 agactatgat tttattctac gagctctaga ctctggttac aaggtatcta atatcagcga
     8881 ttattttggt atttctattc gaaaacatag tagaaatact gcgaatactc aaggatggag
     8941 gcaacgtaaa tgttttaatt tggcttggac gttacataag gaaaggttga aaaaaggtta
     9001 tgaagttaca agcagcatac caagatatgg acgttttatc aaatatggtg ataaaatcca
     9061 cgccatatct aataaattat tagttaaggg gatttcttca aaaaaattat cctataagat
     9121 agcgataata gtagctgctg ctgttatttc cccatatcag tttcaatatt taatttatcg
     9181 attcattggc aagataataa aaaagactct atgaaaatac tttacatcat accaagttta
     9241 aaaaaatgtg ggccagtaaa tgtttgctta tcattggcaa aaaatatctc ggaaaatcat
     9301 agtgtttcta tattggcttt tcgcaatgga aattccttta atgattttta ttcttgctgt
     9361 gataatgtta agataatacc aatttataat ctttttgcca tagcaagatt tattgctgcc
     9421 gagaaatttc agattatcca ttcgcattgt ttggtacctg attttttatt atctttgttt
     9481 agcttctttt tcaggaataa atttatccca atatcgacaa tacataatta tattgatatt
     9541 gattatattt tcagtaaagg actttttata ggtaagttga tgggagtcat taatcggctt
     9601 tcattaagta aaattaagaa cttagtttca tgttctttag ctgttaaata ttattgtgat
     9661 gttgcttatg atataagaag tactgcaatt agtaacggag ttcctatttc tccatatata
     9721 gatgagatgc aacaagaatg caataaaaaa tttattgatt tttattatgt tggtgttctg
     9781 acagaacgca aaaatgttga cttactcata cagtcatttc atttatataa aagaaaatat
     9841 aaaaatgaag accgattgca tgtgattggc ggaggggagt tgttggaagt tttaaaaaaa
     9901 aataacaagt gcgattatat tattttttat ggccctcaag taaatccatg gcctattatt
     9961 aaatctttag acatttatgt gagtagctct agagctgaag ggatgccgtt ggcattatta
    10021 gaagcgttat caataggaaa ggcatatatt tgttcaaata ttgaaccgca ctgtgaggtc
    10081 catcatgttg ttaatggtgg tattatttgc tcctttgata aagatgattt tgttaaagct
    10141 tttcatcata tgagatattg ggatctaaaa ccaaaaaatg agtatattct tgagaggttt
    10201 aagaataatt atgcagatta tataatggct gggaaatatc tgattaagta tgaggagtta
    10261 ctcaaggaac atgaatgaca taaggttttc tgtgttaatg tctctatata aaaatgagtc
    10321 tgaaaaattc ttggatgatt gtttttctag cgtatatgat cagacgttac ctgctaatga
    10381 gataactctg gtaattgatg gcccaattcc caattcactt gaatatgttg tgttaaaatg
    10441 gatggttttt ttacctataa atgtggttag acttgaaaaa aatgttggat tgggccaagc
    10501 attaaactat ggaattaaag cttgttcaaa tgatattatt ataagaatgg atactgatga
    10561 tatttgtaaa agaaacagat ttgaagtttt agtaaaaaaa ttgaattcaa ataataggtt
    10621 agctgtagtc ggctcttgta tcgaagagtt tgttcatctt ccaagtaata ttatctcagt
    10681 aagaactgtt ccactagatc ctgaatccat aaggaaagaa atcttagtta gaaatccttt
    10741 caatcatatg tctgttgcat tcagaaaaaa atttattgaa agcgttggtg gatatgtcca
    10801 tcatcatttt atggaagatt ataatctttg gttacgagta gtggcatctg gatttgatgt
    10861 gtgtaacatt aatgagtcgt taatattagc tagagttggt gataatatgt tggctaggcg
    10921 aaaagggctg aggtatataa aaagtgaatt ccaactttat cggctaaaag ttaaacttgg
    10981 tttgcagtca catatatctg gattctgcat tttgttagta agaagcattc cgcgattact
    11041 ccctctaaag gtcttaaaaa ttatttacca atatattcgg aagtaattat ataataattc
    11101 tgaagattgc actcttattt tttcttagtt gtatctttgt atgttaacat tacgtttaaa
    11161 ccgaaccgct aagacggtaa tttcgtgaca ggagtaaaca atgtcaaagc aacagatcgg
    11221 cgtcgtcggt atggcagtg
//

</pre>