LOCUS       AB811603               19922 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain:
            D-M3219-54.
ACCESSION   AB811603
VERSION     AB811603.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 19922)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..19922
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="D-M3219-54"
                     /db_xref="taxon:562"
                     /note="serogroup:O18ac"
     gene            <1..897
                     /gene="wcaM"
     CDS             <1..897
                     /gene="wcaM"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="BAQ00680.1"
                     /translation="ILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDSDILISDH
                     VIERINCTNGKINWGIGIGLAGSTYDNNYPENQAVKNFVVANITGSDCRQLIHVENGK
                     HFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIKGK
                     YLSIPQNFRVNDIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKPASLELHNKPQH
                     LFMRNINVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAMNEKGQSSVDI
                     DRINHHIVNVEKINFRLPERRE"
     gene            1060..1965
                     /gene="galF"
     CDS             1060..1965
                     /gene="galF"
                     /note="O018ac_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00681.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQAVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2338..3423
                     /gene="rmlB"
     CDS             2338..3423
                     /gene="rmlB"
                     /note="O018ac_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ00682.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNLESLA
                     EISDSERYSFEHADICDAEAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSGLDDEKKKNFRFHHISTDEVYGDLPHPDEVNSNETLPLFTEMTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVFTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDADKISRELGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRH"
     gene            3423..4322
                     /gene="rmlD"
     CDS             3423..4322
                     /gene="rmlD"
                     /note="O018ac_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ00683.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIALDVHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNAAAHTAVDKAESEPEFAQLLNATSVEAIAKAANEVGAWVIHY
                     STDYVFPGTGEIPWQEEDATAPLNVYGETKLAGEKALQEHCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPEVAGLYHLVAS
                     GTTTWHDYAALVFEEARKAGIPLALNKLNAVPTTVYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            4380..5255
                     /gene="rmlA"
     CDS             4380..5255
                     /gene="rmlA"
                     /note="O018ac_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ00684.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLHYKVQPSPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMDAAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLQPKSNYAVTGLYFYDNYVVEMAKNLKPSARGELEITDINRIYMEQGHLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAYRKGFIDAEQVKVLAEPL
                     KKNAYGQYLLKMIKG"
     gene            5263..5820
                     /gene="rmlC"
     CDS             5263..5820
                     /gene="rmlC"
                     /note="O018ac_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ00685.1"
                     /translation="MNVIKTEIPDVLIFEPKVFGDERGFFFESYNQRVFEEAVGRKVE
                     FVQDNHSKSRKGVLRGLHYQLEPYAQAKLVRCIEGEVFDIAVDIRKSSPFFGKWVGVT
                     LSAENKRQLWIPEGFAHGFVVISDTAEFVYKTNNYYSQQAERSIIFDDKDLGIAWPLN
                     THYILSEKDLNAPTFKKISSNEYFK"
     gene            5817..7064
                     /gene="wzx"
     CDS             5817..7064
                     /gene="wzx"
                     /note="O018ac_06"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="BAQ00686.1"
                     /translation="MSLIKNSFWNLCGYVLPAIVTLPALGIMGRKLGPELFGVFTLAL
                     AVVGYASIFDAGLTRAVIREVAIEKDNEENKLKIISSATVVIIYLSLAASLLLFFFSG
                     HIALLLNISETFFHNVSVSLKILAASIPLFLITQIWLSILEGEERFGLLNIYKSITGV
                     ILAISPALFILIKPSLMYAIIGLVLARFLCFILAFIICHDKVLKAKLTIDIPTIKRLF
                     MFGGWITVSNIISPVLSYFDRFIVSNQLGAANVAFYTAPSEIISRLSIIPGAFSRALF
                     PRLANANNSAERYKTKRLITISLLIIITPIFCIGVLFSEKIMVLWMGASFFGEPGLVL
                     SILLIGFIFNGLAQVPFASIQSRGHAKITAFVHLLELFPYLLLLFYLIKAHGVVGAGI
                     AWSVRMIVDYIALSLLDGKYINK"
     gene            7166..8311
                     /gene="wzy"
     CDS             7166..8311
                     /gene="wzy"
                     /note="O018ac_07"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="BAQ00687.1"
                     /translation="MFSLLGTKSRITSPLPLHFLPWLLTLIVGISNYDQFYEFNERSF
                     YSLLIWFTVIFIFYFIGELVNYKRENINVYYGLSHIKYECKKYWIIVIPISLYTIFEI
                     YMVGMGGADGFFLNLRLANTLEGYTGKKFILMPAVYPLMMAMFAIVCLTKTSKLNKYS
                     IYFWMFLYCIGTMGKFSILTPILTYLIIYDFKHRLKVKKTIKFTLLIIILALTLHFTR
                     MAENDHSTFLSILGLYIYSPIIALGQLNEVNSSHFGEYTFRFIYAITNKIGLIKELPV
                     NTILDYSYVPVPTNVYTALQPFYQDFGYTGIIFGAVLYGLIYVSLYTAGVRGNNTQAL
                     LIYALFSVSSATAFFAETLVTNLAGNVKLVLCTILLWRFTVICKPAQ"
     CDS             8320..9228
                     /note="O018ac_08"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00688.1"
                     /translation="MATYNGEAFIKNQILSLQQQTFSNWRLFIQDDGSTDNTISIIKN
                     FQKSDSRIRLVDDNLKGQGAGKNFLSLIKYSETDYTIYCDQDDIWLENKIFELVKYAN
                     EIKLNVSDAPSLVYADGYAYMDGEGTIDFSGISNNHADQLKDFLFFNGGYQGCSIMFN
                     RAMTKFLLNYRGFVYLHDDITTLAAYALGKVYFLPKYLMLYRQHTNAVTGIKTFRNGL
                     TSKFKSPVNYLLSRKHYQVKKSFFECNSSILSETNKKVFLDFISFCESNNKFTDFFKL
                     WRGGFRLNNSRTKLLLKFLIRRKFSE"
     CDS             9225..10013
                     /note="O018ac_09"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00689.1"
                     /translation="MISILTPTFNRQHTLSRLFNSLILQTDKDFEWIIIDDGSIDATA
                     VLVEDFRKKCDFDLIYCYQENNGKPMALNAGVKACRGDYIFIVDSDDALTPDAIKLIK
                     ESIHDCLSEKESFSGVGFRKAYIKGGIIGNDLNNSSEHIYYLNATEISNLINGDVAYC
                     FKKESLVKNPFPRIEDEKFVPELYIWNKITDKAKIRFNISKVIYLCEYLDDGLSKNFH
                     NQLKKYPKGFKIYYKDQRKREKTYIKKTKMLIRYLQCCYYEKIK"
     CDS             10010..11116
                     /note="O018ac_10"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00690.1"
                     /translation="MKILFVITGLGLGGAEKQVCLLADKLSLSGHHVKIISLGHMSNN
                     KVFPSENNVNVINVNMSKNISGVIKGCVRIRDVIANFKPDIVHSHMFHANIITRLSVI
                     GIKNRPGIISTAHNKNEGGYFRMLTYRITDCLSDCCTNVSKEAVDEFLRIKAFNPAKA
                     ITMYNGIDTNKFKFDLLARREIRDGINIKNDDILLLAAGRLTLAKDYPNLLNAMTLLP
                     EHFKLIIIGDGELRDEINMLIKKLQLSNRVSLLGVKKNIAPYFSACDIFVLSSRWEGF
                     GLVVAEAMSCERIVVGTDSGGVREVIGDDDFLVPISDSTQLASKIEKLSLSQIRDHIG
                     FRNRERILKNFSIDTIIMQWQELYGTIICSKHER"
     CDS             11458..12561
                     /note="O018ac_11"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00691.1"
                     /translation="MTARTTKVLHLQLLPLLSGVQRVTLNEISALYTDYDYTLVCSKK
                     GPLTKALLEYDVDCHCIPELTREITVKNDFKALFKLYKFIKKEKFDIVHTHSSKTGIL
                     GRVAAKLARVGKVIHTVHGFSFPAASSKKSYYLYFFMEWIAKFFTDKLIVLNVDDEYI
                     AINKLKFKRDKVFLIPNGVDTDKFSPLENKIYSSTLNLVMVGRLSKQKDPETLLLAVE
                     KLLNENVNVKLTLVGDGELKEQLESRFKRQDGRIIFHGWSDNIVNILKVNDLFILPSL
                     WEGMPLAILEALSCGLPCIVTNIPGNNSLIEDGYNGCLFEIRDCQLLSQKIMSYVGKP
                     ELIAQQSTNARSFILKNYGLVKRNNKVRQLYDN"
     gene            12704..14110
                     /gene="gnd"
     CDS             12704..14110
                     /gene="gnd"
                     /note="O018ac_12"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00692.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAQGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            14357..15523
                     /gene="ugd"
     CDS             14357..15523
                     /gene="ugd"
                     /note="O018ac_13"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00693.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            15613..16647
                     /gene="wzz"
     CDS             15613..16647
                     /gene="wzz"
                     /note="O018ac_14"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00694.1"
                     /translation="MAIIAKLWRLKIILSVRVMMRVENNNVSGQNHDPEQIDLIDLLV
                     QLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGP
                     AVPKVSDIQASLIGRYSTAFSALAETLDNQEEPEKLTIEPTVKNQSLPLAVSYVGETP
                     EGAQKQLAKYIQQVDDQVNEELEQDLKDNIALQMKNLQDSLKTQEVVAQEQKDLRIRQ
                     IQEALQYANQAQVTKPQIQQTQDVTQDTMFLLGSEALESMIKHEATRPLVFSSSYYQT
                     RQNLLDIDNLDVDKLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLG
                     RNALRNYNAK"
     CDS             16815..18143
                     /note="O018ac_15"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase of IS4"
                     /protein_id="BAQ00695.1"
                     /translation="MHIGQALDLVSRYDSLRNPLTSLGDYLDPELISRCLAESGTVTL
                     RKRRLPLEMMVWCIVGMALERKEPLHQIVNRLDIMLPGNRPFVAPSAVIQARQRLGSE
                     AVRRVFTKTAQLWHNATPHPQWCGLTLLAIDGVFWRTPDTPENDAAFPRQTHAGNPAL
                     YPQVKMVCQMELTSHLLTAAAFGTMKNSENELAEQLIEQTGDNTLTLMDKGYYSLGLL
                     NAWSLAGEHRHWMIPLRKGAQYEEIRKLGKGDHLVKLKTSPQARKKWPGLGNEVTARL
                     LTVTRKGKVCHLLTSMTDAMRFPGGEMADLYSHRWEIELGYREIKQTMQLSRLTLRSK
                     KPELVEQELWGVLLAYNLVRYQMIKMAEHLKGYWPNQLSFSESCGMVMRMLMTLQGAS
                     PGRIPELMHDLASMGQLVKLPTRRERAFPRVVKERPWKYPTAPKKSQSVA"
     CDS             18233..18742
                     /note="O018ac_16"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="BAQ00696.1"
                     /translation="MRSGNCKCQTRNQKGVPMGNEKSLAHTRWNCKYHIVFAPKYRRQ
                     VFYREKRRAIGCILRKLCEWKSVRILEAECCADHIHMLVEIPPKMSVSGFMGYLKGKS
                     SLMLYEQFGDLKFKYRNREFWCRGYYVDTVGKNTAKIQDYIKHQLEEDKMGEQLSIPY
                     PGSPFTGRK"
     gene            complement(18982..19593)
                     /gene="hisI"
     CDS             complement(18982..19593)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ00697.1"
                     /translation="MLTERQRRELDWEKTDGLIPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTN
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ"
ORIGIN      
        1 atcttacgtc agggatttca taaccagatt atcggtgcca atatcaccaa ttgtaagttc
       61 agcgacttac agggcgacgc cattgaatgg aacgtggcaa ttaacgacag tgatattttg
      121 atctccgacc atgtgatcga gcgcatcaac tgtactaacg gcaaaatcaa ctggggcatt
      181 ggcataggcc ttgcgggaag tacctacgat aataattatc cggaaaacca ggcagtgaaa
      241 aactttgtcg tggcgaatat cacgggatca gattgtcggc aactgatcca tgttgaaaat
      301 ggtaaacatt ttgttatccg taatatcaaa gctcgtaata tcacgccgga tttcagtaag
      361 aaagcaggta ttgataacgc cacagttgct atttatggtt gtgacaactt tgtgattgat
      421 aatattgaaa tgattaatag tgccgggatg ttaattggct atggggtaat taaaggcaaa
      481 tatctctcga taccgcagaa tttccgagtg aatgatattc aactggataa tactcatctt
      541 gcttataaat tgcgcggcat ccaaatctcc gccgggaatg ctgtctcctt tgtggcgctg
      601 actaacattg agatgaagcc tgcgtcgctt gagctacaca ataaaccgca acaccttttt
      661 atgcgaaata tcaatgtgat gcaggaatcc tctgttggac ccgcattgag catgaacttc
      721 gacatgcgca aagacgtacg cggtgtcttt atggcgaaaa aagaaacact gctgtcactt
      781 gcaaatgttc atgcgatgaa tgaaaaagga caaagctccg tcgatatcga caggattaat
      841 caccatattg ttaatgtgga aaagattaac tttagattgc cggaacggag agagtagatt
      901 tgcgaccatt cctggaaaaa tggagccata cttaggaaca atgctactgc aatccacaac
      961 gaagcggcgt aacatcacaa gtaattcagt aatcaattca gggtaattga tgctggcgaa
     1021 aaaaatcgaa caagctataa ttcagcaacc attttacagg tggatgaaat aatgacgaat
     1081 ttaaaagcag ttattcctgt agcgggtctt gggatgcata tgttgcctgc cactaaggcg
     1141 attcccaaag agatgctacc gatcgtcgac aagccaatga ttcagtacat cgttgacgag
     1201 attgtggctg cagggatcaa agaaatcctc ctggtaactc acgcttccaa gaacgcggtc
     1261 gaaaaccact tcgacacctc ttatgaatta gaatctctcc ttgaacagcg cgtgaagcgt
     1321 caactgcttg cggaagtgca gtccatctgt ccaccgggcg tgaccattat gaacgtgcgt
     1381 cagggcgaac ctttaggttt gggccactcc attttatgtg cacgacctgc tattggtgac
     1441 aacccatttg tcgtggtact gccagacgtt gttatcgatg acgccagcgc cgacccgctg
     1501 cgttacaacc ttgctgccat gattgctcgt ttcaacgaaa cgggccgcag ccaggtgctg
     1561 gcaaaacgta tgccgggtga cctctctgaa tactccgtta ttcagaccaa agaaccactg
     1621 gatcgtgaag gtaaagtcag ccgcattgtt gaatttatcg aaaaaccgga tcagccgcag
     1681 acgctggact cagacatcat ggccgtgggc cgttatgtgc tttctgccga tatttggccg
     1741 gaactggaac gtactcagcc tggtgcatgg ggacgtattc agctgactga tgccattgct
     1801 gagttggcaa aaaaacaagc agttgacgca atgctgatga ctggggacag ttacgactgc
     1861 ggaaagaaaa tgggttatat gcaagcgttt gtgaagtatg ggctgcgtaa cctgaaggag
     1921 ggcgctaagt tccgcaaagg cattgagaag ttgttaagcg agtaacaaat tcctgactgg
     1981 aagtgtcggt cagtaagtaa ttaaaaacgg cagtgaagat tcatagcata agttttgctc
     2041 attgaatctc actgccgttg tcttttttat aagtacaata aaaacagcat gttagcttgc
     2101 aatcatagtt caaatttttc caggattttc cttgtttcta cagctgtttg gtaagacaat
     2161 tagcgtttga atttttcgga tttggcacga gtgggttacg ctcgtcacat cgtggaaatg
     2221 tacgcagtgc tctggtagct gttaagccag gggcggtagc gtgcattaat gcatctatta
     2281 atcaaatctg gagcagtcta tttcacagca tgctctctgg ctatatggaa taaaaaagtg
     2341 aagatacttg ttactggtgg cgcaggattt attggttctg ctgttgttcg tcacataata
     2401 aataatacgc aagatagtgt tgttaatgtc gataaattaa catacgccgg aaacctggaa
     2461 tcgctcgctg aaatttctga ttctgaacgt tattcatttg agcatgcaga tatctgcgat
     2521 gccgaagcga tggctcgtat tttcgcacag caccagccag acgcggtgat gcacctggca
     2581 gcagagagcc acgttgaccg ctcaataact ggccctgcgg catttattga aaccaatatt
     2641 gtgggtactt atgttctttt agaagcggcg cgcaattatt ggtctggtct ggatgatgaa
     2701 aagaaaaaaa acttccgctt tcatcatatt tctactgatg aggtgtatgg tgacttaccc
     2761 catccggatg aagtaaatag caatgaaacg ttgccgctat ttacggaaat gacagcatac
     2821 gcgccaagta gtccatattc tgcttctaaa gcttccagcg atcatttggt tcgcgcatgg
     2881 aaacgtactt atggtttacc gaccattgtg actaattgct cgaacaacta tggtccttat
     2941 catttcccgg aaaagcttat tccactggtt attcttaatg cactggaagg taaggcatta
     3001 cctatttatg gcaaaggaga tcagatccgc gactggttgt atgtagagga tcatgctcga
     3061 gcgttatata ccgtcgtaac cgaaggtaaa gcgggcgaaa cttataacat tggtggacac
     3121 aacgaaaaga aaaacatcga cgtagtgttc actatttgtg atttgttgga tgagatagtc
     3181 ccgaaagaga aatcttatcg tgagcaaatt acctatgttg ctgatcgccc agggcatgat
     3241 cgccgttatg caattgatgc cgataaaatt agccgcgaat tgggctggaa accacaggaa
     3301 acgtttgaga gcgggattcg taaaactgtg gaatggtatc tgtccaatac aaaatgggtt
     3361 gataatgtga aaagtggtgc ctatcaatcg tggattgaac agaactatga gggccgccac
     3421 taatgaatat cctccttttt ggcaaaacag ggcaggttgg ttgggaacta cagcgtgctc
     3481 tggcacctct gggtaatttg attgctcttg atgttcactc cactgattac tgtggtgatt
     3541 ttagtaaccc tgaaggtgtg gctgaaaccg ttagaagcat tcggcctgat attattgtca
     3601 acgcagccgc tcacaccgca gtagacaaag cagaatcaga accggagttt gcacaattac
     3661 tgaacgcgac gagtgtcgaa gcgatcgcga aagcagccaa tgaagtcggc gcttgggtta
     3721 ttcactactc tactgactac gtatttccgg ggaccggtga aataccatgg caggaggagg
     3781 atgcaaccgc accgctaaat gtttacggtg aaaccaagtt agcaggagaa aaagcattac
     3841 aagagcattg tgcgaagcac cttattttcc ggaccagctg ggtctatgca ggtaaaggaa
     3901 ataacttcgc caaaacgatg ttgcgtctgg caaaagagcg tgaagaatta gccgttatta
     3961 atgatcagtt tggtgcgcca actggcgcag agttgctggc tgattgtacg gcacatgcca
     4021 ttcgtgtggc actgaataaa ccggaagtcg caggtttgta ccatctggta gccagtggta
     4081 ccacaacctg gcacgattat gctgcgctgg tttttgaaga ggcgcgcaaa gcaggcattc
     4141 cccttgcact caacaagctc aacgcagtac caacaacagt ctatcctaca ccagctcgtc
     4201 gtccacataa ctctcgcctt aatacagaaa aatttcagca gaactttgcg cttgtcttgc
     4261 ctgactggca ggttggtgtg aaacgcatgc tcaacgaatt atttacgact acagcaattt
     4321 aatagttttt gcatcttgtt cgtgatggtg gaacaagatg aattaaaagg aatgatggaa
     4381 tgaaaacgcg taaaggtatt attttagcgg gtggttctgg tacacgtctt tatcctgtga
     4441 ctatggctgt cagtaaacag ctgttaccga tttatgataa accgatgatc tattacccgc
     4501 tctctacact gatgttggcg ggtattcgcg atattttgat tatcagcacg ccacaggata
     4561 ctcctcgttt tcaacaactg ctgggtgatg ggagccagtg ggggctaaat cttcactaca
     4621 aagtgcaacc gagtccggat ggtcttgcgc aggcatttat catcggtgaa gagtttatcg
     4681 gtggtgatga ttgtgctttg gtacttggtg ataatatctt ctacggtcac gacctgccta
     4741 agttaatgga tgccgctgtt aacaaagaaa gtggtgcaac ggtatttgcc tatcacgtta
     4801 atgatcctga acgctatggt gtcgttgagt ttgataaaaa cggtacggca attagcctcg
     4861 aagaaaaacc gctacaacca aaaagtaatt atgcagtaac cgggctttat ttctatgata
     4921 actacgttgt ggaaatggcg aaaaatctta agccttctgc ccgcggtgaa ctggaaatta
     4981 ccgatattaa ccgtatttat atggaacagg ggcatttatc tgttgccatg atgggacgtg
     5041 gttatgcatg gctggacacg gggacacatc agagtcttat tgaagcaagc aacttcattg
     5101 ccaccattga agagcgccag ggactaaagg tttcctgccc agaagaaatt gcttatcgta
     5161 aaggatttat tgacgcagag caggttaagg tattagccga gccgctgaag aaaaacgctt
     5221 atggtcagta tttgctgaaa atgattaaag gttagtaata aaatgaatgt tattaaaaca
     5281 gaaattccag acgtactgat ttttgaaccg aaagtttttg gtgacgagcg cggtttcttt
     5341 ttcgaaagct ataaccagag ggtttttgag gaagctgtag gtcgcaaagt tgagtttgtt
     5401 caggataacc attctaaatc gagaaaagga gtattgcggg gattgcatta tcaattagag
     5461 ccgtatgcgc aagcaaaact tgtgcgttgc attgagggtg aagtatttga tattgctgta
     5521 gatatacgga agtcatctcc attttttggt aaatgggttg gtgtaacatt atccgctgaa
     5581 aataaacgtc aattatggat ccctgaaggg tttgctcatg gttttgtggt gattagtgat
     5641 actgcggaat ttgtctataa aacgaacaat tattacagtc aacaagcaga gcgaagcata
     5701 atttttgatg ataaagactt agggattgct tggccattga atactcatta tattctttca
     5761 gaaaaagatt taaatgcgcc aacatttaag aaaatatcga gtaatgagta ttttaaatga
     5821 gtttaatcaa aaacagtttt tggaaccttt gcgggtatgt acttccagct attgtgacac
     5881 taccagcttt gggtattatg gggcgaaaat taggcccaga attatttggt gtattcactt
     5941 tggcattagc tgttgtgggt tatgcaagca tttttgatgc aggccttact cgcgcagtga
     6001 tacgagaagt cgcaattgaa aaagataatg aagaaaataa gttgaaaatt atttcttcag
     6061 cgacagttgt aattatttat ttgagtttgg ccgcctcact cttattattt ttttttagtg
     6121 gtcatatcgc attgctactg aacattagtg agactttttt tcataatgta agtgtctcgc
     6181 ttaaaattct cgcagcatcc ataccattat ttttgattac tcaaatatgg ttgtcaattt
     6241 tagaaggtga agaaagattt ggtttactta atatctacaa atcaattacg ggagtgatat
     6301 tagcaatctc accggcatta tttatactta ttaaaccctc tttgatgtat gcgataatag
     6361 gcttagttct agcaaggttt ttatgtttta ttttggcttt tataatttgt cacgataaag
     6421 tgcttaaagc taaactaaca atcgatatac caacaattaa aagattgttt atgttcggtg
     6481 gttggattac agttagtaat atcatcagcc ctgtgctatc atattttgat aggtttattg
     6541 tttcaaatca acttggggct gctaatgttg ctttttatac tgcaccatca gaaattattt
     6601 ctcggcttag tataattcca ggtgcgtttt caagagcctt attcccaaga ttagctaatg
     6661 caaataattc cgctgaaaga tataaaacga aaagattaat tacaatttca cttttaataa
     6721 tcatcacccc tattttttgt attggcgtgt tattttcaga gaagataatg gttttatgga
     6781 tgggggcatc attttttggt gagcctggtt tggtattatc aatattactg attggcttta
     6841 tttttaatgg attggcacaa gtaccatttg ccagtattca atcccgaggt catgctaaga
     6901 taactgcatt tgttcatctc ttagagttgt ttccttattt attactttta ttttacctca
     6961 taaaagcaca tggggttgtt ggcgcgggta ttgcgtggtc agtgaggatg atagtagatt
     7021 atatagcatt aagtcttttg gacggtaagt atattaataa ataaaattca aaatgcaagt
     7081 taataactca tggctttatt tgggtaggtg acaatttata atgatatata tattaacttt
     7141 aactcttctt ctagttatag ccataatgtt ttctcttctc ggcacaaaaa gtaggatcac
     7201 atctccatta cctttgcatt ttttaccatg gttactaact ttaattgtcg ggataagtaa
     7261 ttacgatcaa ttttacgagt ttaatgaaag aagcttttac tctttgttga tttggtttac
     7321 agttattttt atattttatt tcatagggga actggttaat tataaacgtg aaaatataaa
     7381 tgtttattat ggtctttcac atattaaata tgaatgtaaa aaatattgga tcattgtcat
     7441 cccaatttca ttatatacca ttttcgaaat atatatggtt ggtatggggg gagcagatgg
     7501 attctttctc aatttacgtc ttgcaaatac attggagggc tatacgggta aaaaatttat
     7561 cttaatgcct gctgtatatc ctctaatgat ggctatgttc gcaattgttt gtctaacaaa
     7621 aacttccaaa ttaaataaat actccattta tttctggatg tttttgtatt gtattggcac
     7681 aatgggaaaa ttttcaatat taacgccaat attgacatat ttaattattt atgacttcaa
     7741 acatagatta aaagtaaaaa aaacaataaa gtttacattg ttgataatta tattagcttt
     7801 aactttgcat tttacacgta tggctgagaa tgaccactca acatttttat ctattttagg
     7861 gctctatatt tattcaccaa taattgcttt aggccagttg aatgaagtaa atagtagtca
     7921 ttttggtgag tatacgttta gattcatata tgctataact aataaaattg gccttattaa
     7981 agaattgcca gtaaatacta ttcttgacta ttcatacgtt cctgtaccaa caaatgtata
     8041 tactgcactt caaccatttt accaggattt tggttatact ggcatcatat ttggagcagt
     8101 attatacgga ctaatatatg tgagtttata cacggccggt gttcgtggaa ataatacaca
     8161 ggcattactg atttacgcat tgttttcagt tagcagtgca acggctttct tcgctgaaac
     8221 gctagtaacg aatttagctg gaaatgtgaa gttagtatta tgtaccatct tactatggcg
     8281 atttacagta atatgcaaac cagcacagta accattctaa tggccaccta caatggcgag
     8341 gccttcatca aaaatcagat tttgtcacta caacaacaaa cattttctaa ctggcggtta
     8401 tttattcagg atgatgggtc tacagacaat actatatcta taataaaaaa cttccaaaaa
     8461 tctgactcca gaattcggct agttgatgat aatttgaaag gtcaaggtgc aggaaaaaat
     8521 tttttatcgc tgataaagta cagcgagaca gattatacaa tttattgtga ccaagatgat
     8581 atttggttag aaaacaaaat atttgaatta gtaaagtatg caaatgaaat taaattgaat
     8641 gtatcagatg cgccttcgct agtttatgct gatggctatg cttatatgga tggtgagggt
     8701 acaatcgatt tttctgggat atctaacaat catgctgatc aattaaagga ttttcttttt
     8761 tttaatggtg gataccaagg atgttctatt atgttcaatc gtgcaatgac caaatttctt
     8821 ctgaattatc gaggatttgt atatctacat gacgatatca caacattagc tgcatacgct
     8881 cttggtaaag tttattttct cccgaaatac cttatgttat atagacagca cacgaatgcg
     8941 gtaactggta tcaaaacatt ccgcaatgga ttgacttcta aatttaaatc accagtaaac
     9001 tatcttttat cacgaaaaca ttatcaggta aaaaaatctt tttttgaatg taacagctct
     9061 atcttatcag agacgaataa aaaagttttt ttggatttta tttcattttg tgaatcaaat
     9121 aataaattta cagatttttt taagttatgg cgaggtgggt ttagattaaa taacagtaga
     9181 actaaattat tattaaaatt cttaatacgg agaaaattta gcgaatgatt tcaatactta
     9241 cacctacttt taatcggcaa catactttat caaggctatt caattctctt atattacaaa
     9301 ctgataaaga ttttgagtgg ataataattg atgatggtag tatagatgca acagcggtac
     9361 ttgtagaaga ttttagaaaa aaatgtgatt ttgacttgat ttattgctat caggaaaata
     9421 atggtaagcc catggcttta aacgctggtg ttaaagcttg tagaggcgat tatatcttta
     9481 ttgttgacag tgatgatgca ctaactcccg atgccataaa attaattaaa gaatcaatac
     9541 atgattgctt atctgagaag gaaagtttca gcggagtcgg ttttagaaaa gcatatataa
     9601 aaggggggat tattggtaat gatttaaata attcttcaga acatatatac tatttaaatg
     9661 cgactgagat tagcaattta ataaatggtg atgttgcata ttgttttaaa aaagaaagtt
     9721 tggtaaaaaa tccattcccc cgtatagaag atgaaaaatt tgttccagaa ttatatattt
     9781 ggaataaaat aactgacaag gcgaagattc gatttaacat aagcaaagtt atatatcttt
     9841 gtgagtatct tgatgatggt ctttctaaaa atttccataa ccagcttaaa aaatacccaa
     9901 aggggtttaa gatttattac aaagatcaaa gaaaacgaga gaaaacttat ataaaaaaaa
     9961 caaagatgct aattagatat ttgcaatgtt gttattatga gaaaataaaa tgaaaatact
    10021 atttgtcatt acaggtttag gccttggagg tgctgagaag caggtttgtc ttttagctga
    10081 taaattaagt ttaagcgggc accatgtaaa gattatttca cttggacata tgtctaataa
    10141 taaagtcttt cctagcgaaa ataatgttaa tgtcattaat gtaaatatgt caaaaaacat
    10201 ttctggagtt ataaaaggtt gtgtcagaat tagagatgtt atagctaatt tcaaaccaga
    10261 cattgtacac agtcatatgt ttcatgcaaa cattatcact agattgtctg taattggaat
    10321 caaaaacaga cctggtatta tatcaactgc acataataaa aatgaaggtg ggtatttcag
    10381 aatgctcaca tatagaataa ccgattgttt aagtgattgt tgtacaaatg ttagcaaaga
    10441 agcagtggat gagtttttac ggataaaagc ctttaatccc gctaaagcaa ttactatgta
    10501 taatgggata gataccaata aatttaaatt tgatttattg gcaaggaggg aaattcgaga
    10561 cggtattaat ataaaaaatg atgatatatt attacttgct gcaggtcgtt taacgttagc
    10621 taaagattat cctaatttat tgaatgcaat gactctgctt cctgaacact ttaaacttat
    10681 tattattggt gatggtgaat tgcgtgacga aattaatatg cttataaaaa aattgcaatt
    10741 atctaatagg gtgtccttgt tgggagttaa aaaaaatatt gctccctatt tttctgcatg
    10801 tgatattttt gttctctctt ctcgttggga aggatttgga ttagtcgtgg cagaagctat
    10861 gtcatgtgag cgaattgttg ttggcacgga ttcaggggga gtaagagaag ttattggtga
    10921 cgatgatttt cttgtaccca tatctgattc aacacaactt gcaagcaaaa ttgaaaaatt
    10981 gtctttgagc cagatacgtg atcacattgg ttttcggaat cgtgagcgta ttttaaaaaa
    11041 tttctcaata gatactatta ttatgcagtg gcaagaactc tatggaacta taatttgctc
    11101 aaaacatgaa aggtagattt atatttggaa cgtgtctttt gtttgaattt aattcaatct
    11161 caattgagat ttttgtattt caaaaatacc atcatagcta acgatgattg gtatttattt
    11221 taagatgctt tctataaata tattgacgtt tttaatgcgc cgaaacgatt gggctgggaa
    11281 cagagaagta aaactgtttt gagaatgaag agtttttgag atgtttatgg atattaaaaa
    11341 ttgatccagt gaattaatta tttataataa atcaagattt aatgttaata aatgataatc
    11401 ttttctgaca ctcatattaa ttatgagtgg tacgtttggt aaacggtaaa ctattatatg
    11461 acagctagaa caactaaagt tttgcactta caattactcc cactcttaag tggcgttcaa
    11521 agggtaacat taaacgaaat tagtgcgtta tatactgatt atgattatac actagtttgc
    11581 tcaaaaaaag gtccactaac aaaagcattg ctggaatatg atgtcgattg tcattgtatc
    11641 cccgaactta cgagagaaat taccgtaaag aatgatttta aagcattgtt caagctttat
    11701 aagttcataa aaaaagaaaa atttgacatt gtgcatacac attcttcaaa aacaggtatt
    11761 ttggggcgag ttgctgccaa attagcacgt gttggaaagg tgatccacac tgtacatggt
    11821 ttttcttttc cagccgcatc tagtaaaaaa agttattacc tttatttttt catggaatgg
    11881 atagcaaagt tctttacgga taagttaatc gtcttgaatg tagatgatga atatatagca
    11941 ataaacaaat taaaattcaa gcgggataaa gtttttttaa ttcctaatgg agtagacact
    12001 gataagtttt ctcctttaga aaataaaatt tatagtagca ccttgaatct agtaatggtt
    12061 ggtagattat ccaagcaaaa agatcctgag acattattgc ttgctgttga aaaactgctg
    12121 aatgaaaatg ttaatgttaa gctgacactt gtaggagatg gtgaactaaa agaacagtta
    12181 gaaagcaggt tcaaacggca agatggacgt ataatttttc atggatggtc agataacatt
    12241 gttaatattt taaaagttaa tgatcttttt atattacctt ctctttggga gggtatgcca
    12301 ttagcaattt tagaagcatt gagctgtgga cttccatgta tagtcactaa tattccaggt
    12361 aataatagct taatagaaga tggctataat ggttgtttgt ttgaaattag agattgtcag
    12421 ttattatctc aaaaaatcat gtcatatgtt ggtaagccag aactgattgc acagcaatct
    12481 accaatgcac gatcatttat tctgaaaaat tatggattag ttaaaagaaa taataaggtc
    12541 agacagctat atgataatta aatgaaaccg aaaagttaaa aaagaacagg tttttcaaag
    12601 tgaaaataaa attacagttt ttttattgca atgattaacg taacatctgc attacattca
    12661 agccgcacaa ccccgcggtg accacccctg acaggagtaa acaatgtcaa agcaacagat
    12721 cggcgtcgtc ggtatggcag tgatgggacg caacctcgcg ctcaacatcg aaagccgtgg
    12781 ttataccgtc tctattttca accgttcccg tgaaaagacg gaagaagtta ttgccgaaaa
    12841 tccaggcaag aaactggttc cttactatac ggtgaaagag ttcgttgaat ctcttgaaac
    12901 gcctcgtcgc atcctgttaa tggttaaagc aggtgcaggc acggatgctg ctattgattc
    12961 cctgaaacca tatctcgata aaggcgatat catcattgat ggtggtaata ccttcttcca
    13021 ggacaccatt cgtcgtaacc gcgagctttc tgcacaaggc tttaacttca tcggtacggg
    13081 tgtttccggt ggtgaagagg gcgcgctgaa aggaccttct atcatgcctg gtgggcagaa
    13141 agaggcctat gaactggttg ctcctatcct gaccaaaatc gccgccgtgg ctgaagatgg
    13201 tgaaccatgc gttacctata ttggtgccga tggcgcaggt cactatgtga agatggttca
    13261 caacggtatt gaatacggtg atatgcaact gattgctgaa gcctattctc tgctgaaagg
    13321 tggtctgaat ctctctaacg aagaactggc acaaaccttt accgagtgga ataacggtga
    13381 actgagcagt tacctgatcg acatcactaa agacatcttc accaaaaaag atgaagacgg
    13441 taactacctg gttgatgtga tcctggatga agcagcaaac aaaggtacgg gtaaatggac
    13501 cagtcagagc gcgctggatc tcggtgagcc actgtcgctg attactgagt ctgtgtttgc
    13561 acgctacatc tcttcactaa aagatcagcg cgtggctgcg tctaaagtac tgtcgggtcc
    13621 acaagcgcag ccagcaggcg acaaagcaga gttcattgaa aaagttcgcc gtgcgcttta
    13681 tctgggtaag attgtttctt acgcgcaggg cttctctcag ctgcgtgctg cgtctgaaga
    13741 gtacaactgg gatctgaact acggtgaaat cgcgaagatt ttccgtgctg gctgcatcat
    13801 ccgtgcgcag ttcctgcaga aaatcaccga tgcttatgcc gaaaatccgc agatcgctaa
    13861 cctgctgctg gctccgtact tcaagcaaat tgccgatgac taccagcagg ctctgcgtga
    13921 tgtcgttgct tatgcagtac agaacggtat cccggttccg accttcgccg ctgcggttgc
    13981 ctattacgat agctaccgtg ccgctgttct gcctgcgaac ctgatccagg cacagcgtga
    14041 ctatttcggt gcacatactt ataagcgcat tgataaagaa ggtgtgttcc atactgaatg
    14101 gctggattga tccgatttaa ccaacaataa aattgaggcc cggtgtatat tgcaccgggt
    14161 ttttttgcca attatcttat agactaaatt tcactgctta atattaactt aataaatatc
    14221 agctatcctt ataaagaaaa tctgaattgt ttttcgttgc gttgaccatc gaacgacgta
    14281 gcgttaaaac ttttagctct tatcaggatg ctaaaaacat catgattcac agttaagtta
    14341 attctgagag catgaaatga aaattaccat ttccggtact ggctatgtag gcttgtcaaa
    14401 cgggcttcta atcgcacaaa atcatgaggt tgtggcatta gatattttac cgtcacgcgt
    14461 tgctatgctg aatgatcgga tatctcctat tgttgataag gaaattcagc agtttttgca
    14521 atcagataaa atacacttta atgccacatt agataaaaat gaagcctacc gggatgctga
    14581 ttatgtcatt atcgccactc caaccgacta tgatcctaaa actaattatt tcaatacatc
    14641 cagtgtagaa tcagtaatta aagacgtagt tgagataaat ccttatgcgg ttatggtaat
    14701 caaatcaacg gttcccgttg gttttaccgc agcgatgcat aagaaatatc gcactgaaaa
    14761 tattattttc tctccggaat ttctccgtga aggtaaagct ctttacgata atctccatcc
    14821 ttcacgtatt gtcattggcg agcgttcaga acgcgcagaa cgttttgctg cgttgttaca
    14881 ggaaggcgcg attaagcaaa atatcccgac cctgtttacc gactccactg aagcagaagc
    14941 gattaaactg tttgctaata cctatctggc gatgcgcgta gcatacttta atgaactgga
    15001 tagctatgca gaaagtttag gtctgaatac tcgtcagatt atcgaaggtg tttgtctcga
    15061 tccgcgtatt ggcaaccatt acaacaatcc gtcgtttggc tatggtggtt attgtctacc
    15121 gaaagatacc aagcagttac tggcgaacta ccagtctgtg ccgaataacc tgatctcggc
    15181 aattgtcgat gcaaaccgca cgcgtaaaga ctttattgcc gatgccattt tgtcacgcaa
    15241 gccgcaagtg gtgggtattt atcgtctgat tatgaagagc ggttcagata acttccgcgc
    15301 gtcttccatt caggggatta tgaaacgtat taaggcgaaa ggcgttgaag tgatcatcta
    15361 cgagccggtg atgaaagaag actcattctt caactctcgc ctggaacgtg atctcgccac
    15421 cttcaaacaa caagccgacg tcattatctc caaccgtatg gcagaagagc ttaaggatgt
    15481 ggcagataag gtctacaccc gcgatctctt tggcagcgac taacatcctg ttatcagggc
    15541 gattttcgcc ctgattgtct tatgttccct ttgtaataat tcattatttt tatcatttat
    15601 cctatagcat tcatggcgat tatcgctaaa ctatggcgac ttaaaattat tttgtccgtt
    15661 agggtaatga tgagagtaga aaataataat gtttctgggc aaaaccatga cccggaacag
    15721 attgatttga ttgatttact ggtccaacta tggcgtggca agatgactat catcatttct
    15781 gtcattgtgg ctattgccct ggctataggg tatctggccg ttgccaaaga aaagtggact
    15841 tcaacagcta tcgttactca acctgatgtg gggcaaatcg ctggttatac caacgcgatg
    15901 aatgtgattt acggtccggc agtaccgaaa gtctccgaca ttcaggcttc acttatcgga
    15961 cgttacagca ctgcattttc agcattagca gaaacgctgg ataatcagga agaacctgaa
    16021 aaactgacca ttgagcctac cgttaaaaat cagtcattac ctttagcggt ttcttatgtt
    16081 ggtgaaacac ctgaaggtgc gcagaaacag ctggcgaagt atatccagca agttgacgac
    16141 caggtaaatg aagaactgga acaagacctg aaagacaaca tcgcgctgca aatgaaaaac
    16201 ttgcaggatt ctctgaagac gcaggaagtg gtcgctcaag agcagaaaga tctgcgtatc
    16261 cgtcagattc aggaagcgtt gcagtatgcg aatcaggcgc aggtgacaaa gccgcagatt
    16321 caacagacgc aggacgtaac ccaggatact atgttccttt tggggagcga agcgctggag
    16381 tcgatgatta agcacgaggc gacccgtccg ttggtgttct catcaagcta ctatcagact
    16441 cgtcaaaacc tgctggatat cgacaatctt gacgttgata aacttgatat tcatgcttac
    16501 cgctatgtaa tgaaaccgac gttacctatt cgtcgcgata gcccgaaaaa ggcaattacc
    16561 ttgattctgg cggtgctgct gggcggcatg gttggcgcgg ggattgtgct tgggcgtaac
    16621 gcgctgcgta attacaacgc gaaataatat tattgtgcat ttaagagaaa cgggcagggt
    16681 ggtgacacca tgcccgtttt tttgtgcaca gaaaaccccc agctaggctg taatgccgat
    16741 cagttaagga tcagttgacc gatccagtgg ctgtgtaaga atccggaaac gctcactcgt
    16801 ttccggattt ttttatgcac attggacagg cccttgattt ggtatcccgt tacgattctc
    16861 tgcgtaaccc actgacttct ctgggggatt acctcgaccc cgaactcatc tctcgttgcc
    16921 ttgccgaatc aggtactgta acgctacgca agcgccgtct tcccctcgaa atgatggtct
    16981 ggtgtattgt tggcatggcg cttgagcgta aagaacctct tcaccagatt gtgaatcgcc
    17041 tggacatcat gctgccgggc aatcgcccct tcgttgcccc cagtgccgtt attcaggccc
    17101 gccagcgctt gggaagtgag gctgtccgcc gcgtgttcac gaaaacagcg cagctctggc
    17161 ataacgccac gccgcatccg caatggtgcg gcctgaccct gctggccatc gatggtgtgt
    17221 tctggcgcac accggataca ccagagaacg atgcagcctt cccccgccag acacatgccg
    17281 ggaacccggc gctctacccg caggtcaaaa tggtctgcca gatggaactg accagccatc
    17341 tgctgacggc tgcagccttc ggcacgatga agaacagcga aaatgagctt gctgagcaac
    17401 ttatagaaca aaccggcgat aacactctga cgttaatgga caaaggttat tactcactgg
    17461 gactgttaaa tgcctggagc ctggcgggag aacaccgcca ctggatgatc cctctcagaa
    17521 agggagcgca atatgaagag atcagaaaac tgggtaaagg cgatcatctg gtgaagctga
    17581 aaaccagccc gcaggcacga aaaaagtggc cgggactggg aaatgaggtg acagcccgcc
    17641 tgctgaccgt gacgcgcaaa ggaaaagtct gccatctgct gacgtcgatg acggacgcca
    17701 tgcgcttccc cggaggagaa atggcggatc tgtacagtca tcgctgggaa atcgaactgg
    17761 gatacaggga gataaaacag acgatgcaac tgagcaggct gacgctgaga agtaaaaagc
    17821 cggagcttgt ggagcaagag ctgtggggtg tcttactggc ttataatctg gtgagatatc
    17881 agatgattaa aatggcggaa catctgaaag gttactggcc gaatcaactg agtttctcag
    17941 aatcatgcgg aatggtgatg agaatgctga tgacattgca gggcgcttca ccgggacgta
    18001 taccggagct gatgcacgat cttgcaagta tgggacaact tgtgaaatta ccgacaagaa
    18061 gggaaagggc cttcccgaga gtggtaaagg agaggccctg gaaatacccc acagccccga
    18121 aaaagagcca gtcagttgct taactgactg gcattacagc taggctgggg gttccggaaa
    18181 gctttcagct ttgagccagt tattaaaacc ccttttgatt tgttaaaaca ccttgcggtc
    18241 tggcaactgc aagtgtcaaa caagaaatca aaagggggtc ccaatgggga acgaaaagag
    18301 cttagcgcac acccgatgga actgtaaata tcacatagta tttgcgccaa aataccgaag
    18361 acaggtgttc tacagagaga agcgtagagc aataggctgt attttgagaa agctgtgtga
    18421 gtggaaaagt gtacggattc tggaagctga atgctgtgca gatcatatcc atatgcttgt
    18481 ggagatcccg cccaaaatga gcgtatcagg ctttatggga tatctgaaag ggaaaagcag
    18541 tctgatgctt tacgagcagt ttggtgattt gaaattcaaa tacaggaaca gggagttctg
    18601 gtgcagaggg tattacgtcg atacggtggg taagaacacg gcgaagatac aggattacat
    18661 aaagcaccag cttgaagagg ataaaatggg agagcagtta tcgattccct atccgggcag
    18721 cccgtttacg ggccgtaagt aacgaagttg gatgcaaatg tcagatcgtg tgcgcctgtt
    18781 agggcgcggc tggtaagaga gccttatagg cgcatttgaa aaacctccgg ctatgccgga
    18841 ggatatttat tttgccggat gcgatgctgg cgcatcttat ccggcctacg tgtgttgaga
    18901 taatgtgtag gcacgataag cttgcgcatc gggcaatggc tccggatgcg acaacaacat
    18961 cgcatccggt cagcacgcca ctcactgatg ccgtttacgc aggttctcaa tcaccgttgt
    19021 taaatccaga tcctgatcct gcaacaacac cagcaggtga tacatcaaat cagacgcctc
    19081 gttggtcagt tcaaagcggt catgtaccgt tgctgccagt gcggtttcca cgccttcttc
    19141 gcccactttc tgcgcaatgc gtttggtgcc gctggcatac agtttggcgg tgtaggaggt
    19201 ttccgggtcg gcagatttac gttcggcgag cagttgttcc agttgataca ggaacagcca
    19261 ctggtgagcg gtgtcgccga agcagctgtt ggtgcctttg tggcaggttg gcccgatggg
    19321 attcgccagc accagtaacg tgtcgttgtc gcagtccggc gcaatgctca ccacattgag
    19381 gaaattgccc gaggtttcgc ctttggtcca cagtcgctgt ttagtgcgcg agaagaaggt
    19441 aactttaccg ctttcgatgg ttttgtctaa ggcttccggg ttcatgtagc ccagcattaa
    19501 cacttcgccg gataccgcgt gttgcacaat caccggtatc agaccgtcgg ttttttccca
    19561 gtccagttcg cgacgttgtc gttctgttaa catatcctga tctccacgcc ctgtgttgcc
    19621 aggtacgctt ttaattcgcc aatattgatt atttgtttgt ggaatacgga agctgccaac
    19681 gtaccgtcaa cgtcggcatc gcggaaggct tcgaggaagt gttccatggt gcctgcgcca
    19741 ccggaggcaa tcagcgggac gtggcaaact tcacgcactt ttttcagttg ttcgaggtcg
    19801 tagccgttac gcacgccgtc ctgattcatc atgttgagga cgatttctcc ggcaccgcgt
    19861 ttttgcactt cctgcaccca atcgagtgtt tcccactgag tgacgcgggt gcggctttca
    19921 tc
//