LOCUS       AB811601               17903 bp    DNA     linear   BCT 13-MAY-2015
DEFINITION  Escherichia coli DNA, O-antigen biosynthetic locus, strain:
            F11119-41.
ACCESSION   AB811601
VERSION     AB811601.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1
  AUTHORS   Iguchi,A., Iyoda,S., Kikuchi,T., Ogura,Y., Katsura,K., Ohnishi,M.,
            Hayashi,T. and Thomson,N.R.
  TITLE     A complete view of the genetic diversity of the Escherichia coli
            O-antigen biosynthesis gene cluster
  JOURNAL   DNA Res. 22 (1), 101-107 (2015)
   PUBMED   25428893
  REMARK    DOI:10.1093/dnares/dsu043
REFERENCE   2  (bases 1 to 17903)
  AUTHORS   Iguchi,A., Iyoda,S. and Ohnishi,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-MAR-2013) Contact:Atsushi Iguchi University of
            Miyazaki, Faculty of Agriculture; Gakuen-kibanadai-nishi 1-1,
            Miyazaki, Miyazaki 889-2192, Japan
FEATURES             Location/Qualifiers
     source          1..17903
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="F11119-41"
                     /db_xref="taxon:562"
                     /note="serogroup:O16"
     gene            <1..903
                     /gene="wcaM"
     CDS             <1..903
                     /gene="wcaM"
                     /codon_start=1
                     /transl_table=11
                     /protein_id="BAQ00645.1"
                     /translation="YAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILIS
                     DHVIERINCTNGKINWGIGIGLAGSTYDNNYPEDQAVKNFVVANITGSDCRQLIHVEN
                     GKHFVIRNIKARNITPDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGYGVIK
                     GKYLSIPQNFRVNDIQLDNTHLAYKLRGIQISAGNAVSFVALTNIEMKRASLELHNKP
                     QHFFMRNINVMQESSVGPALSMNFDMRKDVRGVFMAKKETLLSLANVHAVNEKGQSSV
                     DIDRINHHIVNVEKINFRLPELRE"
     gene            1066..1971
                     /gene="galF"
     CDS             1066..1971
                     /gene="galF"
                     /note="O016_01"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="BAQ00646.1"
                     /translation="MDEIMTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYI
                     VDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVT
                     IMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNE
                     TGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGR
                     YVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQA
                     FVKYGLRNLKEGAKFRKGIEKLLSE"
     gene            2344..3429
                     /gene="rmlB"
     CDS             2344..3429
                     /gene="rmlB"
                     /note="O016_02"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6 dehydratase"
                     /protein_id="BAQ00647.1"
                     /translation="MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLTYAGNRESLA
                     DVSDSERYVFEHADICDAPAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIV
                     GTYVLLEAARNYWSALDSDKKNSFRFHHISTDEVYGDLPHPDEVNNTEELPLFTETTA
                     YAPSSPYSASKASSDHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEG
                     KALPIYGKGDQIRDWLYVEDHARALYTVVTEGKAGETYNIGGHNEKKNIDVVLTICDL
                     LDEIVPKEKSYREQITYVADRPGHDRRYAIDAEKIGRALGWKPQETFESGIRKTVEWY
                     LSNTKWVDNVKSGAYQSWIEQNYEGRQ"
     gene            3429..4328
                     /gene="rmlD"
     CDS             3429..4328
                     /gene="rmlD"
                     /note="O016_03"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="BAQ00648.1"
                     /translation="MNILLFGKTGQVGWELQRALAPLGNLIAFDVHSTDYCGDFSNPE
                     GVAETVRSIRPDIIVNAAAHTAVDKAESEPEFAQLINATSVEAIAKAANEVGAWVIHY
                     STDYVFPGNGDMPWLETDATAPLNVYGETKLAGEKALQEYCAKHLIFRTSWVYAGKGN
                     NFAKTMLRLAKEREELAVINDQFGAPTGAELLADCTAHAIRVALNKPDVAGLYHLVAS
                     GTTTWYDYAALVFEEARKAGIPLALNKLNAVPTTAYPTPARRPHNSRLNTEKFQQNFA
                     LVLPDWQVGVKRMLNELFTTTAI"
     gene            4386..5267
                     /gene="rmlA"
     CDS             4386..5267
                     /gene="rmlA"
                     /note="O016_04"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="BAQ00649.1"
                     /translation="MKMRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGG
                     DDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDKNGTAISL
                     EEKPLEPKSNYAVTGLYFYDNDVVQMAKNLKPSARGELEITDINRIYLEQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKGFIDVEQVRKLAVPL
                     IKNNYGQYLYKMTKDSN"
     gene            5267..5824
                     /gene="rmlC"
     CDS             5267..5824
                     /gene="rmlC"
                     /note="O016_05"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="BAQ00650.1"
                     /translation="MNVIRTEIEDVLILEPRVFGDDRGFFYESFNQSAFEHILGYPVS
                     FVQDNHSRSSKNVLRGLHFQRGEYAQDKLVRCTHGAVFDVAVDIRPNSVSFGKWVGVL
                     LSADNKQQLWIPKGFAHGFLVLSDIAEFQYKTTNYYHPESDCGICWNDERIAIDWPQT
                     SGLILSPKDERLFTLDELIRLKLIA"
     gene            5821..7068
                     /gene="wzx"
     CDS             5821..7068
                     /gene="wzx"
                     /note="O016_06"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen flippase"
                     /protein_id="BAQ00651.1"
                     /translation="MNTNKLSLRRNVIYLAVVQGSNYLLPLLTFPYLVRTLGPENFGI
                     FGFCQATMLYMIMFVEYGFNLTATQSIAKAADSKDKVTSIFWAVIFSKIVLIVITLIF
                     LTSMTLLVPEYNKHAVIIWSFVPALVGNLIYPIWLFQGKEKMKWLTLSSILSRLAIIP
                     LTFIFVNTKSDIAIAGFIQSSANLVAGIIALAIVVHEGWIGKVTLSLHNVRRSLADGF
                     HVFISTSAISLYSTGIVIILGFISGPTSVGNFNAANTIRNALQGLLNPITQAIYPRIS
                     STLVLNRVKGVILIKKSLTCLSLIGGAFSLILLLGASILVKISIGPGYDNAVIVLMII
                     SPLPFLISLSNVYGIQVMLTHNYKKEFSKILIAAGLLSLLLIFPLTTLFKEIGAAITL
                     LATECLVTSLMLMFVRNNKLLVC"
     gene            7076..8179
                     /gene="glf"
     CDS             7076..8179
                     /gene="glf"
                     /note="O016_07"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="BAQ00652.1"
                     /translation="MYDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTED
                     CEGIQIHKYGAHIFHTNDKYIWDYVNDLVEFNRFTNSPLAIYKDKLFNLPFNMNTFHQ
                     MWGVKDPQEAQNIINAQKKKYGDKVPENLEEQAISLVGEDLYQALIKGYTEKQWGRSA
                     KELPAFIIKRIPVRFTFDNNYFSDRYQGIPVGGYTKLIEKMLEGVDVKLGIDFLKDKD
                     SLASKAHRIIYTGPIDQYFDYRFGALEYRSLKFETERHEFPNFQGNAVINFTDANVPY
                     TRIIEHKHFDYVETKHTVVTKEYPLEWKVGDEPYYPVNDNKNMELFKKYRELASREDK
                     VIFGGRLAEYKYYDMHQVISAALYQVKNIMSTD"
     gene            8179..9345
                     /gene="wzy"
     CDS             8179..9345
                     /gene="wzy"
                     /note="O016_08"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="BAQ00653.1"
                     /translation="MIYLVISVFLITAFICLYLKKDIFYPAVCVNIIFALVLLGYEIT
                     SDIYAFQLNDATLIFLLCNVLTFTLSCLLTESVLDLNIRKVNNAIYSIPSKKVHNVGL
                     LVISFSMIYICMRLSNYQFGTSLLSYMNLIRDADVEDTSRNFSAYMQPIILTTFALFI
                     WSKKFTNTKVSKTFTLLVFIVFIFAIILNTGKQIVFMVIISYAFIVGVNRVKHYVYLI
                     TAVGVLFSLYMLFLRGLPGGMAYYLSMYLVSPIIAFQEFYFQQVSNSASSHVFWFFER
                     LMGLLTGGVSMSLHKEFVWVGLPTNVYTAFSDYVYISAELSYLMMVIHGCISGVLWRL
                     SRNYISVKIFYSYFIYTFSFIFYHESFMTNISSWIQITLCIIVFSQFLKAQKIK"
     CDS             9342..10340
                     /note="O016_09"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00654.1"
                     /translation="MKMYFLNDLNFSRRDAGFKARKDALDIASDYENISVVNIPLWGG
                     VVQRIISSVKLSTFLCGLENKDVLIFNFPMAKPFWHILSFFHRLLKFRIVPLIHDIDE
                     LRGGGGSDSVRLATCDMVISHNPQMTKYLSKYMSQDKIKDIKIFDYLVSSDVEHRDVT
                     DKQRGVIYAGNLSRHKCSFIYTEGCDFTLFGVNYENKDNPKYLGSFDAQSPEKINLPG
                     MQFGLIWDGDSVETCSGAFGDYLKFNNPHKTSLYLSMELPVFIWDKAALADFIVDNRI
                     GYAVGSIKEMQEIVDSMTIETYKQISENTKIISQKIRTGSYFRDVLEEVIDDLKTR"
     CDS             10321..10911
                     /note="O016_10"
                     /codon_start=1
                     /transl_table=11
                     /product="putative acetyltransferase"
                     /protein_id="BAQ00655.1"
                     /translation="MILKLAKRYGLCGFIRLVRDVLLTRVFYRNCRIIRFPCYIRNDG
                     SINFGENFTSGVGLRLDAFGRGVIFFSDNVQVNDYVHIASIESVTIGRDTLIASKVFI
                     TDHNHGSFKHSDPMSSPNIPPDMRTLESSAVVIGQRVWLGENVTVLPGTIIGNGVVVG
                     ANSVVRGSIPENTVIAGVPAKIIKKYNHETKLWEKA"
     CDS             10896..12014
                     /note="O016_11"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00656.1"
                     /translation="MGKSIVVVSAVNFTTGGPFTILKKFLAATNNKENVSFIALVHSA
                     KELKESYPWVKFIEFPEVKGSWLKRLHFEYVVCKKLSKELNATHWICLHDITANVVTK
                     KRYVYCHNPAPFYKGILFREILMEPSFFLFKMLYGLIYKINIKKNTAVFVQQFWMKEK
                     FIKKYSINNIIVSRPEIKLSDKSQLTDDDSQFKNNPSELTIFYPAVPRVFKNYELIIS
                     AARKLKEQSNIKFLLTISGTENAYAKYIISLAEGLDNVHFLGYLDKEKIDHCYNISDI
                     VCFPSRLETWGLPLSEAKERGKWVLASDFPFTRETLGSYEKKAFFDSNNDDMLVKLII
                     DFKKGNLKKDISDANFIYRNENVLVGFDELVNFITEEH"
     CDS             12016..12810
                     /note="O016_12"
                     /codon_start=1
                     /transl_table=11
                     /product="putative glycosyltransferase"
                     /protein_id="BAQ00657.1"
                     /translation="MVYIIIVSHGHEDYIKKLLENLNADDEHYKIIVRDNKDSLLLKQ
                     ICQHYAGLDYISGGVYGFGHNNNIAVAYVKEKYRPADDDYILFLNPDIIMKHDDLLTY
                     IKYVESKRYAFSTLCLFRDEAKSLHDYSVRKFPVLSDFIVSFMLGINKTKIPKESIYS
                     DTVVDWCAGSFMLVRFSDFVRVNGFDQGYFMYCEDIDLCLRLSLAGVRLHYVPAFHAI
                     HYAHHDNRSFFSKAFRWHLKSTFRYLARKRILSNRNFDRISSVFHP"
     gene            12938..14344
                     /gene="gnd"
     CDS             12938..14344
                     /gene="gnd"
                     /note="O016_13"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="BAQ00658.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRIDKEGVFHTEWLD"
     gene            14593..15759
                     /gene="ugd"
     CDS             14593..15759
                     /gene="ugd"
                     /note="O016_14"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="BAQ00659.1"
                     /translation="MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISP
                     IVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIATPTDYDPKTNYFNTSSVESVIK
                     DVVEINPYAVMVIKSTVPVGFTAAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
                     GERSERAERFAALLQEGAIKQNIPMLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ESLGLNSRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAI
                     VDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELKDVADKVYTRDLFGSD"
     gene            15869..16885
                     /gene="wzz"
     CDS             15869..16885
                     /gene="wzz"
                     /note="O016_15"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen chain length determinant protein"
                     /protein_id="BAQ00660.1"
                     /translation="MRTWKFPSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKM
                     TIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVIYGQAAPKVSD
                     LQETLIGRFSSAFSALAETLDNQEEREKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKL
                     AQYIQQVDDKVNQELEKDLKDDIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQY
                     ANQAQVTKPQIQQTGEDITQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLD
                     IESLKVDDLDIHAYRYVMKPMLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRN
                     YNAK"
     gene            complement(16981..17592)
                     /gene="hisI"
     CDS             complement(16981..17592)
                     /gene="hisI"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /protein_id="BAQ00661.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TLESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQGLDLTTVIENLRKRHQ"
ORIGIN      
        1 tacgccatct tacgccaggg atttcataac cagattatcg gtgccaacat caccaattgt
       61 aagttcagcg acttacaagg cgacgccatt gaatggaacg tggcaattaa cgaccgtgat
      121 attttgatat ctgaccatgt catcgagcgc atcaactgta ccaacggcaa aatcaactgg
      181 ggcatcggca taggccttgc gggaagcact tatgataaca actacccgga agaccaggca
      241 gtgaaaaact ttgtcgtggc gaatatcacg ggatcggatt gtcggcagtt gatacatgtt
      301 gaaaatggta aacattttgt tattcgtaat atcaaagccc gcaatatcac gccggatttc
      361 agtaagaaag cgggcattga taacgcgaca gtcgctattt acggttgtga caatttcgtg
      421 attgataata ttgaaatgat taatagcgcc gggatgttaa tcggctatgg ggtaattaaa
      481 ggcaaatatc tctcgatacc gcaaaatttc cgggtgaatg atattcaact ggataatact
      541 catcttgctt ataaattgcg cggcattcaa atctccgccg ggaatgctgt ttcctttgtg
      601 gcgctaacta acattgagat gaagcgtgcg tcgctggagt tacacaacaa accgcaacat
      661 ttttttatgc gaaatatcaa tgtgatgcag gaatcctcag ttggacccgc attgagcatg
      721 aactttgaca tgcgcaaaga cgttcgtggt gtttttatgg cgaaaaaaga aacactgctg
      781 tctcttgcaa atgttcatgc ggtgaatgaa aaaggacaaa gctccgtcga tatcgacagg
      841 attaatcacc atattgttaa tgtggagaag attaacttta gattgccgga actgagggag
      901 tagatttgcg accattcctg gaaaaatgga gtcatactta ggaacaatgc tactgcaatc
      961 cacaacgaag cggcgtaaca tcacaagtaa ttcagtaatc aattcagggt aattgatgct
     1021 ggcgaaaaaa atcgaacaag ctataattca gcaaccattt tacaggtgga tgaaataatg
     1081 acgaatttaa aagcagttat tcctgtagcg ggtctcggga tgcatatgtt gcctgccact
     1141 aaggcgatac ccaaagagat gctaccaatc gtcgacaagc caatgattca gtacattgtt
     1201 gacgagattg tggctgcagg gatcaaagaa atcctcctgg taactcacgc gtccaagaac
     1261 gcggtcgaaa accacttcga cacctcttat gagttagaat cactccttga gcaacgcgtg
     1321 aagcgtcaac tgctggcgga agtacagtcc atctgtccgc cgggcgtgac cattatgaac
     1381 gtgcgtcagg gcgaaccttt aggtttaggc cactccattt tgtgtgcgcg acctgccatt
     1441 ggtgacaacc catttgtcgt ggtactgcca gacgttgtga tcgacgatgc cagcgccgac
     1501 ccgctacgtt acaaccttgc tgccatgatt gcacgtttca acgaaacggg ccgcagccag
     1561 gtgctggcaa aacgtatgcc gggtgacctc tctgaatact ccgtcatcca gactaaagag
     1621 ccgctggacc gtgagggtaa agtcagccgc attgttgaat ttatcgaaaa accggatcag
     1681 ccgcagacgc tggactcaga catcatggcc gtaggtcgct atgtgctttc tgccgatatt
     1741 tggccggaac tggaacgtac tcagcctggt gcatggggac gtattcagtt gactgatgct
     1801 attgccgagc tggcgaaaaa acaatccgtt gatgcaatgc tgatgaccgg cgacagttac
     1861 gactgcggca aaaaaatggg ctatatgcag gcgtttgtga agtatggcct acgcaacctg
     1921 aaagaagggg cgaagttccg taaaggtatt gagaagctgt taagcgaata atgaaaatct
     1981 gaccggatgt aacggttgat aagaaaatta taacggcagt gaaaattcgc agcaagagta
     2041 atttgttgcg aatcttcctg ccgttgtttt atataaacca tcagaataac aacgagttag
     2101 cagtagggtt ttattcaaag ttttccagga ttttccttgt ttccagagcg gattggtaag
     2161 acaattagcg tttgaatttt tcgggtttag cgcgagtggg taacgctcgt cacatcatag
     2221 gcatgcatgc agtgctctgg tagctgtaaa gccaggggcg gtagcgtgca ttaatacctc
     2281 tattaatcaa actgagagcc gcttatttca cagcatgctc tgaagtaata tggaataaat
     2341 taagtgaaaa tacttgttac tggtggcgca ggatttattg gttcagctgt agttcgtcac
     2401 attataaata atacgcagga tagtgttgtt aatgttgata aattaacgta cgccggaaac
     2461 cgggaatcac ttgctgatgt ttctgattct gaacgctatg tttttgaaca tgcggatatt
     2521 tgcgatgcac ctgcaatggc acggattttt gctcagcatc agccggatgc agtgatgcac
     2581 ctggctgctg aaagccatgt tgaccgttca attacaggcc ctgcggcatt tattgaaacc
     2641 aatattgttg gtacttatgt ccttttggaa gccgctcgca attactggtc tgctcttgat
     2701 agcgacaaga aaaatagctt ccgttttcat catatttcta ctgacgaagt ctatggtgat
     2761 ttgcctcatc cagatgaagt aaataataca gaagaattac ccttatttac tgagacgaca
     2821 gcttacgcgc caagcagccc ttattccgca tccaaagcat ccagcgatca tttagtccgc
     2881 gcgtggaaac gtacatatgg tttaccgaca attgtgacta attgctcgaa caactatggt
     2941 ccttatcatt tcccggaaaa gcttattcca ctggttattc ttaatgcact ggaaggtaag
     3001 gcattaccta tttatggcaa aggagatcag atccgcgact ggttgtatgt tgaagatcat
     3061 gcgcgtgcgt tatataccgt cgtaaccgaa ggtaaagcgg gtgaaactta taacattggt
     3121 gggcacaacg aaaagaaaaa catcgatgta gtgctcacta tttgtgattt gctggatgag
     3181 attgtaccga aagagaaatc ttatcgtgag caaatcactt atgttgctga tcgtccggga
     3241 cacgatcgcc gctatgctat tgatgctgag aagattggtc gcgcattggg atggaaacca
     3301 caggaaacgt ttgagagcgg gattcgtaaa acggtggaat ggtacctgtc caatacaaaa
     3361 tgggttgata atgtgaaaag tggtgcctat caatcgtgga ttgaacagaa ctatgagggc
     3421 cgccagtaat gaatatcctc ctttttggca aaacagggca ggtaggttgg gaactacagc
     3481 gtgctctggc acctttgggt aatttgattg cttttgatgt tcactctact gattattgcg
     3541 gtgattttag taatcctgaa ggtgtagctg aaaccgtaag aagcattcgg ccggatatta
     3601 ttgtcaatgc agccgctcac accgcagtag acaaagcaga atcagaaccg gagtttgcac
     3661 aattaattaa cgcaacaagt gtcgaagcga ttgcgaaagc agcaaatgaa gttggagcct
     3721 gggttatcca ttactcgact gattacgtct tccctggaaa tggcgatatg ccatggctgg
     3781 agacggatgc aaccgcacca ctaaatgttt acggtgaaac caagttagcc ggagaaaaag
     3841 cgttacagga atattgcgcg aagcatctta ttttccggac cagctgggtc tatgcaggaa
     3901 aaggaaataa cttcgccaaa acgatgttac gtctggcaaa agagcgtgaa gaattagcgg
     3961 ttattaacga tcagtttggt gcgccaacag gtgctgaact gctggctgat tgtacagcac
     4021 atgccattcg tgtcgcactg aataaaccgg atgtcgcagg cttgtaccat ttggtagcca
     4081 gtggtaccac aacctggtac gattatgctg cgctggtttt tgaagaggcg cgcaaagcag
     4141 gcattcccct tgcactcaac aagctcaacg cagtaccaac aacagcctat cctacaccag
     4201 ctcgtcgtcc acataactct cgccttaata cagaaaaatt tcagcagaac tttgcgcttg
     4261 tcttgcctga ctggcaggtt ggcgtgaaac gaatgctcaa tgaattattt acgactacag
     4321 caatttaata gtttttgcat cttgttcgtg atggtggagc aagatgaatt aaaaggaatg
     4381 atgaaatgaa aatgcgtaaa ggtattattt tagcgggtgg ttctggtaca cgtctttatc
     4441 ctgtgactat ggctgtcagt aaacagctat tacctattta tgataaaccg atgatctatt
     4501 acccgctctc tacactgatg ttggcgggta ttcgcgatat tttgattatc agtacacctc
     4561 aggatactcc tcgttttcaa caattgctgg gtgacggtag ccagtggggc ctgaatcttc
     4621 agtacaaagt gcaacctagc ccagatggcc tcgcgcaggc atttatcatc ggtgaagagt
     4681 ttattggtgg tgatgattgt gctttggttc ttggtgataa tatcttttac ggtcacgatc
     4741 tgccgaagct aatggaggcc gctgttaaca aagaaagtgg tgcaacggta tttgcctatc
     4801 acgttaatga tccagaacgc tatggtgtcg ttgagtttga taaaaacggt acggcaatca
     4861 gtctggaaga aaaaccgtta gaaccaaaga gtaattacgc cgttacaggt ctgtacttct
     4921 atgataacga cgtggttcag atggcgaaaa acttgaagcc gtctgcacgt ggtgagttag
     4981 aaattacaga tattaaccgt atttatcttg agcagggacg tctgtctgtc gcgatgatgg
     5041 ggcgtggcta cgcgtggctg gacacgggga ctcatcagag tctgatagaa gcaagtaatt
     5101 ttattgcgac aattgaagag cgccagggat tgaaggtttc ctgtcctgaa gagattgcat
     5161 ttcgtaaagg ttttattgat gttgagcaag taagaaaatt agctgtacca ctaataaaga
     5221 ataattatgg gcagtatctt tataaaatga cgaaggattc aaattaatga atgtgattag
     5281 aactgaaatt gaagatgtgc taattctgga gccaagagta tttggtgatg atagaggttt
     5341 cttttatgag agctttaatc aatcagcatt tgaacatatt ctaggctatc cggtcagctt
     5401 tgttcaagac aatcactcac gttcatcaaa aaatgtactc agaggccttc actttcaacg
     5461 cggcgagtac gcacaagata aacttgtacg ctgcactcat ggagcagttt ttgatgttgc
     5521 tgttgatatt cgacccaatt cggtatcctt tggtaaatgg gttggtgttc tgctttcagc
     5581 tgataataag cagcagttgt ggataccaaa agggtttgct catggctttt tggttctgtc
     5641 tgatatcgct gaatttcaat ataaaactac aaactattat catcctgaaa gcgattgtgg
     5701 aatatgttgg aatgatgaac gcattgcaat tgattggccc caaacatcag ggttaatcct
     5761 ttcgccaaaa gatgaaaggc tctttacgtt agatgagctt atcagattaa aattaattgc
     5821 atgaatacga ataaattatc tttaagaaga aacgttatat atctggctgt cgttcaaggt
     5881 agcaattatc ttttaccatt gcttacattt ccatatcttg taagaacact tggtcctgaa
     5941 aatttcggta tattcggttt ttgccaagcg actatgctat atatgataat gtttgttgaa
     6001 tatggtttca atctcacagc aactcagagt attgccaaag cagcagatag taaagataaa
     6061 gtaacgtcta ttttttgggc ggtgatattt tcaaaaatag ttcttatcgt cattacattg
     6121 attttcttaa cgtcgatgac cttgcttgtt cctgaatata acaagcatgc cgtaattata
     6181 tggtcgtttg ttcctgcatt agtcgggaat ttaatctacc ctatctggct gtttcaggga
     6241 aaagaaaaaa tgaaatggct gactttaagt agtattttat cccgcttggc tattatccct
     6301 ctaacattta tttttgtgaa cacaaagtca gatatagcaa ttgccggttt tattcagtca
     6361 agtgcaaatc tggttgctgg aattattgca ctagctatcg ttgttcatga aggttggatt
     6421 ggtaaagtta cgctatcatt acataatgtg cgtcgatctt tagcagacgg ttttcatgtt
     6481 tttatttcca catctgctat tagtttatat tctacgggaa tagttattat cctgggattt
     6541 atatctggac caacgtccgt agggaatttt aatgcggcca atactataag aaacgcgctt
     6601 caagggctat taaatcctat cacccaagca atatacccaa gaatatcaag tacgcttgtt
     6661 cttaatcgtg tgaagggtgt gattttaatt aaaaaatcat tgacctgctt gagtttgatt
     6721 ggtggtgctt tttcattaat tctgctcttg ggtgcatcta tactagtaaa aataagtata
     6781 gggccgggat atgataatgc agtgattgtg ctaatgatta tatcgcctct gccttttctt
     6841 atttcattaa gtaatgtcta tggcattcaa gttatgctga cccataatta taagaaagaa
     6901 ttcagtaaga ttttaatcgc tgcgggtttg ttgagtttgt tgttgatttt tccgctaaca
     6961 actcttttta aagagattgg tgcagcaata acattgcttg caacagagtg cttagttacg
     7021 tcactcatgc tgatgttcgt aagaaataat aaattactgg tttgctgagg attttatgta
     7081 cgattatatc attgttggtt ctggtttgtt tggtgccgtt tgtgcgaatg agttaaaaaa
     7141 gctaaacaaa aaagttttag tgattgagaa aagaaatcat atcggtggaa atgcgtacac
     7201 agaggactgt gagggtatcc agattcataa atatggtgca catatttttc ataccaatga
     7261 taaatatata tgggattacg ttaatgattt agtagaattt aatcgtttta ctaattctcc
     7321 actggcgatt tataaagaca aattattcaa ccttcctttt aatatgaata ctttccacca
     7381 aatgtgggga gttaaagatc ctcaagaagc tcaaaatatc attaatgctc agaaaaaaaa
     7441 gtatggtgac aaggtacctg aaaatttgga ggagcaggcg atttcattag ttggggagga
     7501 cttataccaa gcattgataa agggttatac ggagaagcag tggggaagaa gtgcaaaaga
     7561 attgcctgca tttattatta agcgaatccc agtgagattt acgtttgata acaattattt
     7621 ttccgatcgc tatcaaggta ttccggtggg aggctacact aagcttattg aaaaaatgct
     7681 tgaaggtgtg gacgtaaaat taggcattga ttttttgaaa gacaaagatt ctctagcgag
     7741 taaagcccat agaatcatct acactggacc cattgatcag tacttcgact ataggtttgg
     7801 agcgttagaa tatcgctctt taaaatttga gacggaacgc catgaatttc caaacttcca
     7861 agggaatgca gtaataaatt tcactgatgc taatgtacca tataccagaa taattgagca
     7921 taaacatttt gactatgttg agacaaagca tacggttgtt acaaaagaat atccattaga
     7981 gtggaaagtt ggcgacgaac cctactatcc agttaatgat aataaaaaca tggagctttt
     8041 taagaaatat agagagttag ctagcagaga agacaaggtt atatttggcg ggcgtttggc
     8101 cgagtataaa tattatgata tgcatcaagt gatatctgcc gctctttatc aagtgaaaaa
     8161 tataatgagt acggattaat gatctatctt gtaattagtg tctttctcat tacagcattt
     8221 atctgtttat atcttaagaa ggatatattt tatccagccg tatgcgttaa tatcatcttc
     8281 gcactggtct tattgggata tgaaataacg tcagatatat atgcttttca gttaaatgac
     8341 gctacgttga tttttctact ttgcaatgtt ttgacattta ccctgtcatg tttattgacg
     8401 gaaagtgtat tagatctaaa tatcagaaaa gtcaataatg ctatttatag cataccatcg
     8461 aagaaagtgc ataatgtagg cttgttagtt atttcttttt cgatgatata tatatgcatg
     8521 aggttaagta actaccagtt cgggactagc ttacttagct atatgaattt gataagagat
     8581 gctgatgttg aagacacatc aagaaatttc tcagcataca tgcagccaat cattctaact
     8641 acttttgctt tatttatttg gtctaaaaaa tttactaata caaaggtaag taaaacattt
     8701 actttacttg tttttattgt attcatcttt gcaattatac tgaatactgg taagcaaatt
     8761 gtctttatgg ttatcatctc ttatgcattc atcgtaggtg ttaatagagt aaaacattat
     8821 gtttatctta ttacagctgt aggtgttcta ttctccttgt atatgctctt tttacgtgga
     8881 ctgcctgggg ggatggcata ttatctatcc atgtatttgg tcagccctat aatcgcgttt
     8941 caggagtttt attttcagca agtatctaac tctgccagtt ctcatgtctt ttggtttttt
     9001 gaaaggctga tggggctatt aacaggtgga gtctctatgt cgttgcataa agaatttgtg
     9061 tgggtgggtt tgccaacaaa tgtttatact gctttttcgg attatgttta tatttccgcg
     9121 gagctaagct atttgatgat ggttattcat ggctgtattt caggtgtttt atggagattg
     9181 tctcgaaatt acatatctgt gaaaatattt tattcatatt ttatttatac cttttctttc
     9241 attttttatc atgaaagctt catgactaat attagcagtt ggatacaaat aactctttgt
     9301 atcatagtat tctctcaatt tcttaaggcc cagaaaataa agtgaaaatg tattttttga
     9361 atgatttaaa tttctctaga cgcgatgctg gatttaaagc aagaaaagat gcactggaca
     9421 ttgcttcaga ttatgaaaac atttctgttg ttaacattcc tctatggggt ggagtagtcc
     9481 agagaattat tagttctgtt aagcttagta catttctctg cggtcttgaa aataaagatg
     9541 ttttaatttt caatttcccg atggccaaac cattttggca tatattgtca ttctttcacc
     9601 gccttctaaa atttagaata gtacctctga ttcatgatat tgatgaatta agaggaggag
     9661 ggggtagtga ttctgtgcgg cttgctacct gtgatatggt cataagtcac aatccacaaa
     9721 tgacaaagta ccttagtaaa tatatgtctc aggataaaat caaagacata aaaatatttg
     9781 attacctcgt ctcatctgat gtggagcatc gagatgttac ggataagcaa cgaggggtca
     9841 tatatgctgg caacctttct aggcataaat gttctttcat atatactgaa ggatgcgatt
     9901 ttactctctt tggtgtcaac tatgaaaata aagataatcc taaatatctt ggaagttttg
     9961 atgctcaatc tccggaaaag attaacctcc caggcatgca atttggactc atttgggatg
    10021 gagattctgt cgaaacctgt agtggtgcct ttggcgacta tttaaagttt aataaccctc
    10081 ataagacatc tctttatctt tcaatggaac ttccagtatt tatatgggat aaagccgccc
    10141 ttgcggattt cattgtagat aatagaatag gatatgcagt gggatcaatc aaagaaatgc
    10201 aagagattgt tgactccatg acaatagaaa cttataagca aattagtgag aatacaaaaa
    10261 ttatttctca gaaaattcga acaggaagtt acttcaggga tgttcttgaa gaggtgatcg
    10321 atgatcttaa aactcgctaa acgatatggt ctctgtggtt ttattcggct tgttagagat
    10381 gtcttattga ctcgtgtatt ttaccggaac tgtagaatta ttcgatttcc ctgctatatt
    10441 cgcaatgatg gtagcattaa ttttggtgaa aatttcacaa gtggagtcgg tctcaggctg
    10501 gatgcatttg gacgtggcgt gatttttttt tccgataatg tgcaagttaa cgactatgtt
    10561 catatcgcct caattgagag cgttacgata ggtcgggata cgcttattgc aagtaaagta
    10621 tttattaccg atcataatca cggttccttt aagcactctg atccaatgag ttcgccaaat
    10681 atacctccag acatgcgcac gttggaatct tcagctgttg taattggcca gagggtttgg
    10741 ttgggtgaga atgtgacggt tttgcctgga acaattattg gtaatggagt cgtagtcggc
    10801 gccaattctg ttgttagagg ttctattccc gaaaatactg tcattgcggg agtaccagca
    10861 aaaatcataa agaaatacaa tcatgagacc aaattatggg aaaaagcata gtcgttgttt
    10921 ctgcggtcaa ttttaccact ggcggtccat ttaccatttt gaaaaaattt ttggcagcaa
    10981 ctaataataa agaaaatgtc agttttatcg cattagtcca ttctgctaaa gagttaaaag
    11041 aaagttatcc atgggttaaa ttcattgagt ttcctgaggt taaagggtcg tggctaaaac
    11101 gtttgcactt tgaatatgta gtttgtaaaa aactttcaaa agagctgaat gctacgcatt
    11161 ggatttgtct gcatgatatt acggccaatg tcgtcactaa aaaaagatat gtgtattgtc
    11221 ataaccctgc acctttttat aaaggaattt tattccgtga aattcttatg gagcctagct
    11281 ttttcttatt taaaatgcta tacgggctga tatataaaat aaacattaaa aaaaatactg
    11341 cagtgtttgt tcaacaattc tggatgaaag aaaaatttat caagaaatat tctataaata
    11401 acatcattgt cagtcggcca gaaattaaat tatctgataa aagccaactt actgatgatg
    11461 attctcaatt taagaataac ccttctgagt tgacaatatt ttaccctgct gttccacgag
    11521 tatttaaaaa ttacgagctt attattagtg cagcaaggaa attgaaagaa caatccaata
    11581 ttaaatttct gcttactatc agtggtacag aaaatgcgta tgcaaaatat attatcagtc
    11641 ttgcagaagg actggataat gttcatttcc tcgggtactt ggataaagaa aaaatcgatc
    11701 attgttataa tatttcagat atagtttgtt ttccctctag gttagaaaca tggggattgc
    11761 cgttgtctga agctaaagag cgaggtaagt gggtattagc atcagatttc ccatttacta
    11821 gagaaactct tggtagttat gaaaagaaag ctttttttga ttctaataac gatgacatgt
    11881 tagttaaact tattattgac ttcaaaaaag gtaacctcaa aaaagatatc tctgatgcaa
    11941 atttcattta tcgtaatgaa aatgtattag ttgggtttga tgaactagtt aattttatta
    12001 ctgaagaaca ttgaaatggt atatataata atcgtttccc acggacatga agactacatc
    12061 aaaaaattac tcgaaaatct taatgctgac gatgagcact acaagattat cgtacgcgac
    12121 aacaaagact ctctattatt gaaacaaata tgccagcatt atgcaggcct ggactatatt
    12181 agtggaggtg tatacggctt tggtcataat aataatattg cggtggcgta tgtaaaggaa
    12241 aaatatagac ccgcagatga tgattacatt ttgtttttga atcccgatat catcatgaag
    12301 catgatgatt tgctgacata tattaaatat gtcgaaagta agcgttatgc ttttagtaca
    12361 ttatgcctgt tccgagatga agcgaaatct ttacatgatt attccgtaag aaaatttcct
    12421 gtgctttctg attttattgt gtcatttatg ttagggatta ataaaacaaa aattcctaaa
    12481 gaaagtatct attctgatac ggttgttgat tggtgcgcag gatcatttat gctggtacgt
    12541 ttttcagatt ttgtgcgtgt aaatggcttc gatcaaggtt actttatgta ctgtgaagat
    12601 attgacctgt gcttgaggct tagcctggct ggtgtcagac ttcattatgt tcccgctttt
    12661 catgcgatac attatgctca tcatgacaat cgaagttttt tttcaaaagc cttcagatgg
    12721 cacttaaaaa gtacttttag atatttagcc agaaaacgta ttttatcaaa tcgcaacttt
    12781 gatcgaattt catcagtttt tcacccgtaa tataaagccg taagcatata agcatggata
    12841 agctatttat actttaataa gtactttgta tacttatttg cgaacattcc aggccgcgag
    12901 cattcagcgc ggtgatcaca cctgacagga gtatgtaatg tccaagcaac agatcggcgt
    12961 agtcggtatg gcagtgatgg gacgcaacct tgcgctcaac atcgaaagcc gtggttatac
    13021 cgtctctatt ttcaaccgtt cccgtgagaa gacggaagaa gtgattgccg aaaatccagg
    13081 caagaaactg gttccttact atacggtgaa agagtttgtc gaatctctgg aaacgcctcg
    13141 tcgcatcctg ttaatggtga aagcaggtgc aggcacggat gctgctattg attccctcaa
    13201 accatatctc gataaaggag acatcatcat tgatggtggt aacaccttct tccaggacac
    13261 tattcgtcgt aatcgtgagc tttcagcaga gggctttaac ttcatcggta ccggtgtttc
    13321 tggcggtgaa gagggggcgc tgaaaggtcc ttctattatg cctggtggcc agaaagaagc
    13381 ctatgaattg gtagcaccga tcctgaccaa aatcgccgcc gtagctgaag acggtgaacc
    13441 atgcgttacc tatattggtg ccgatggcgc aggtcactat gtgaagatgg ttcacaacgg
    13501 tattgaatac ggcgatatgc agctgattgc tgaagcctat tctctgctta aaggtggcct
    13561 gaacctcacc aacgaagaac tggcgcagac ctttaccgag tggaataacg gtgaactgag
    13621 cagttacctg atcgacatca ccaaagatat cttcaccaaa aaagatgaag acggtaacta
    13681 cctggttgat gtgatcctgg atgaagcggc taacaaaggt accggtaaat ggaccagcca
    13741 gagcgcgctg gatctcggcg aaccgctgtc gctgattacc gagtctgtgt ttgcacgtta
    13801 tatctcttct ctgaaagatc agcgtgttgc cgcatctaaa gttctctctg gtccgcaagc
    13861 acagccagca ggcgacaagg ctgagttcat cgaaaaagtt cgtcgtgcgc tgtatctggg
    13921 caaaatcgtt tcttacgccc agggcttctc tcagctgcgt gctgcgtctg aagagtacaa
    13981 ctgggatctg aactacggcg aaatcgcgaa gattttccgt gctggctgca tcatccgtgc
    14041 gcagttcctg cagaaaatca ccgatgctta tgccgaaaat ccacagatcg ctaacctgtt
    14101 gctggctccg tacttcaagc aaattgccga tgactaccag caggcgctgc gtgatgtcgt
    14161 tgcttatgca gtacagaacg gtattccggt tccgaccttc tccgcagcgg ttgcctatta
    14221 cgacagctac cgtgctgctg ttctgcctgc gaacctgatc caggcacagc gtgactattt
    14281 tggtgcgcat acttataagc gtattgataa agaaggtgtg ttccataccg aatggctgga
    14341 ttaatctgat ttaaccaaca ataaaattga ggcccggcgt atattgcacc gggctttttt
    14401 ttgccaaata tcttatagac taaatttcac tgcttaatat taacttaata aatatcagct
    14461 attcttataa agaaaatctg aattgttttt cgttgcgttg accatcgaac aacgtagcgt
    14521 taaaactttt agctcttatc aggatgctaa aaacatcatg attcacagtt aagttaattc
    14581 tgagagcatg aaatgaaaat caccatttcc ggtactggct atgtaggctt gtcaaacggg
    14641 cttctaatcg cacaaaatca tgaggttgtg gcattagata ttttaccgtc acgcgttgct
    14701 atgctgaatg atcggatatc tcctattgtt gataaggaaa ttcagcagtt tttgcaatca
    14761 gataaaatac actttaatgc cacattagat aaaaatgaag cctaccggga tgctgattat
    14821 gtcatcatcg ccactccaac cgactatgat cctaaaacta attatttcaa tacatccagt
    14881 gtagaatcag taattaaaga cgtagttgag ataaatcctt atgcggttat ggtcatcaaa
    14941 tcaacggttc ccgttggttt taccgcagcg atgcataaga aatatcgcac tgaaaatatt
    15001 atattctccc cggaatttct ccgtgagggt aaagcccttt acgataatct ccatccttca
    15061 cgtattgtca tcggtgagcg ttcagaacgc gcagaacgtt tcgctgctct gttacaggaa
    15121 ggcgcgatta agcaaaatat cccgatgctg tttaccgact ccactgaagc agaagcgatt
    15181 aaactttttg caaacaccta cctggcgatg cgcgtggcgt actttaacga actggatagc
    15241 tatgcagaaa gtttaggtct gaattcccgt caaataatcg aaggcgtttg tctcgaccca
    15301 cgtattggca accattacaa caatccgtcg tttggttatg gtggttattg tctgccgaaa
    15361 gataccaagc agttactggc gaactaccag tctgtgccga ataacctgat ctcggcaatt
    15421 gtcgatgcta accgcacgcg taaagatttt attgccgatg ccattttgtc acgcaagccg
    15481 caagtggtgg gtatttatcg tctgattatg aagagcggtt cagataactt ccgtgcgtct
    15541 tctattcagg ggattatgaa acgtatcaag gcgaaaggtg ttgaagtgat catctacgag
    15601 ccagtgatga aagaagactc attcttcaac tctcgcctgg aacgtgatct cgccaccttc
    15661 aaacaacaag ccgacgtcat tatctctaac cgaatggcag aagagcttaa ggatgtggca
    15721 gataaggtat acacccgcga tctctttggc agcgactaac atcttgttat cagggctatt
    15781 tacgccctga ttgtcttttg ttacttacac aacaattcat tatttttatc acttatccta
    15841 tagcattcac gaggattatc gctaaactat gcggacttgg aaatttccgt cagttagggt
    15901 aatgatgaga gtagaaaata ataatgtttc tgggcaaaac catgacccgg aacagattga
    15961 tttgattgat ttactagtgc agttgtggcg tggcaagatg acaatcatca tttccgtcat
    16021 tgtggctatt gccctggcta ttggatattt ggcagtagcg aaggagaaat ggacgtcaac
    16081 agcaattatc actcagcccg acgtggggca aattgctggc tataacaatg ccatgaatgt
    16141 tatctatggt caggctgcac cgaaagtatc ggatttgcag gagacgttaa ttggtcgctt
    16201 cagttctgcc ttctctgcat tagcagaaac gctggataat caggaagaac gagaaaaact
    16261 taccatcgaa ccttctgtta agaaccagca attaccattg actgtttctt atgttgggca
    16321 aactgcagag ggcgcacaaa tgaagttggc ccaatacatt cagcaagttg acgataaagt
    16381 gaatcaagag ctagaaaagg atctcaaaga cgacattgct ctgggacgga aaaacttgca
    16441 ggactcttta agaacgcagg aagtagtcgc gcaggagcag aaagatctgc gtatccgtca
    16501 gattcaggaa gcgttgcagt atgcgaatca ggcgcaggtg acaaaaccgc agattcaaca
    16561 gactggcgaa gatatcacac aagatacgtt gttccttttg gggagcgaag cgctggagtc
    16621 gatgattaag catgaggcga cccgtccgtt ggtgttctcg ccaaactact atcagactcg
    16681 tcaaaacctg ctggatatcg aaagcttaaa agttgatgat cttgatattc atgcttaccg
    16741 ttatgtgatg aaaccgatgt tacctattcg tcgtgatagc ccgaaaaagg caattacctt
    16801 gattctggcg gtgctgctgg gtggcatggt tggcgcgggg attgtgctgg ggcgtaatgc
    16861 tctacgcaat tacaacgcga agtaatcttt tcggttttaa agaaaaaggg cagggtggtg
    16921 acaccttgcc cgtttttttg ccggatgcgg caacaatatc gcatccgctt accccgcaac
    16981 tcactgatgc cgtttacgca ggttctcaat taccgtcgtt aaatccagcc cctgatcctg
    17041 caacaacacc agcaggtgat acatcaaatc agacgcctcg ttggtcagct caaagcggtc
    17101 atgtaccgtt gctgccagcg cggtttccac gccttcttca cccactttct gcgcaatgcg
    17161 tttggtgccg ctggcataca gtttggcggt gtaggaggtt tccggatcgg cagatttgcg
    17221 ctcggcgagc agttgttcca gttgatacag gaacagccac tggtgagcgg tgtcgccgaa
    17281 gcaactgctg gtgcctttgt ggcaggtcgg gccgatggga ttcgccagca ccagtaacgt
    17341 gtcgttgtcg cagtccgggg caatactcac tacgttgagg aaattgcccg acgtttcgcc
    17401 tttggtccac agtcgctgtt tagtgcgcga gaagaaggtg actttgccgc tttcgagggt
    17461 tttgtctaag gcttccgggt tcatatagcc cagcattagc acttcgccgg ataccgcgtg
    17521 ttgcacaatc accggcataa gtccgtcggt tttttcccag tccagttcgc gacgttgttg
    17581 ttctgttaac atatcctgat ctccacgccc tgtgttgcca ggtacgcttt taattcacca
    17641 atattgatta tttgtttgtg gaatacggaa gctgccagcg cgccgtcaac gtcggcatcg
    17701 cggaaggctt cgaggaagtg ttccatggtg cccgcgccac cggaggcaat cagcgggacg
    17761 tggcaaactt cacgcacttt tttcagttgt tcgaggtcgt aaccgttacg cacgccgtcc
    17821 tgattcatca tattgaggac gatttctccg gcaccgcgtt tttgcacttc ctgtacccag
    17881 tcgagcgttt cccattgagt gac
//