<pre>LOCUS       DQ000315               10484 bp    DNA     linear   BCT 29-JUN-2007
DEFINITION  Escherichia coli O106 O antigen gene cluster, complete sequence.
ACCESSION   DQ000315
VERSION     DQ000315.1
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10484)
  AUTHORS   Wang,W., Perepelov,A.V., Feng,L., Shevelev,S.D., Wang,Q.,
            Senchenkova,S.N., Han,W., Li,Y., Shashkov,A.S., Knirel,Y.A.,
            Reeves,P.R. and Wang,L.
  TITLE     A group of Escherichia coli and Salmonella enterica O antigens
            sharing a common backbone structure
  JOURNAL   Microbiology (Reading, Engl.) 153 (PT 7), 2159-2167 (2007)
   PUBMED   17600060
REFERENCE   2  (bases 1 to 10484)
  AUTHORS   Feng,L., Perepelov,A.V., Wang,W., Shevelev,S.D., Wang,Q.,
            Senchenkova,S.N., Li,Y., Shashkov,A.S., Knirel,Y.A., Reeves,P.R.
            and Wang,L.
  TITLE     Structure Characterization of Escherichia coli O73 O Antigen and
            Identification of O Antigen Gene Clusters of Several E. coli
            Strains Which Share the Common O antigen Backbone with Different O
            Antigen Modification Factors
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 10484)
  AUTHORS   Feng,L., Perepelov,A.V., Wang,W., Shevelev,S.D., Wang,Q.,
            Senchenkova,S.N., Li,Y., Shashkov,A.S., Knirel,Y.A., Reeves,P.R.
            and Wang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-APR-2005) TEDA School of Biological Sciences and
            Biotechnology, Nankai University, 23# HongDa Street, Tianjin
            300457, P.R. China
FEATURES             Location/Qualifiers
     source          1..10484
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:562"
                     /note="serogroup: O106"
     misc_feature    1..10484
                     /note="O antigen gene cluster"
     gene            1158..2162
                     /gene="wbaC"
     CDS             1158..2162
                     /gene="wbaC"
                     /note="mannosyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="WbaC"
                     /protein_id="AAY23741.1"
                     /translation="MKVIVNNFFDGILKRGIPIYTSELVQKLRDNNVQVIYVACPKAF
                     HKLPSWFLNVLFIIVEQLLIPIMGIFYRTKYNIYPYNSSSIIDLLLGKAIVIIHDFIS
                     LKKNKRNLAAIYVKVCIYFSSFLAKKVIFISQSTQRVSKRISLFKCIESILLPNPFFS
                     FEKIANVTEIKDLGYLLLVSGLGDNKDLGTALDYYFSIPREERIPLKILGCGNGISKV
                     NDLIDGRDTDKEIEIIGFVSLEEVVKLYCNSKIVWAHSLAEGYGRTLAEAKLTCKNVI
                     CTRISAFREQMDSNIFFYTYYSEYYEVYSYLVDNSPSVERKALHEHILFENELRKIYE
                     "
     gene            2155..3357
                     /gene="wbaD"
     CDS             2155..3357
                     /gene="wbaD"
                     /note="mannosyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="WbaD"
                     /protein_id="AAY23742.1"
                     /translation="MSNIDINKKQILVLTPRFPFPVIGGDRLRIYKICKELSKHYDLT
                     LLSLCDKREELNYEYDREVFSSVHRVYLSKKKSILNVIFSLFSNTPLQIGYYKSKEFE
                     DKLKQLLPEHSATLSHLIRVGDYVKENKDINFLEMTDAISLNYKRVKEKASLLSLKTF
                     VYSFEQKRLERYERTINNKFSLTTLVSQVDSDYLYPDRPNNVLVCGNGVDAVSLPFSE
                     RKIAKDKKITLVFIGNLYSLQNMDGVRWFTKEVLPFLNKHGNFEFKVIGRITDKDKSW
                     LESQPGVVVTGEVDSITYAAADGHIGVCPIRLGAGIQNKVLEYMALGLPCISSTVGFE
                     GLGAEEGKEIYVANTKEEYLRVLNYFITNLDKYTETALVAKKFIGENFSWEAKLSPYI
                     QKIKESVK"
     gene            3359..4774
                     /gene="manC"
     CDS             3359..4774
                     /gene="manC"
                     /note="mannose-1-phosphate guanylytransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="ManC"
                     /protein_id="AAY23743.1"
                     /translation="MIIPIIMAGGSGTRLWPLSRSLYPKQFLSLINENSLLQETLKRL
                     DGLNCLPPVIVSNNEHRFIVAEQLRQSGVDDFQIILEPVGRNTAPAVALAALKSLELH
                     GDHHMLVLAADHAIQDIEAFHAAVLAAEQESVDNKLVTFGIVPTKPETGYGYIKKGEQ
                     VKNSVFKVNSFVEKPDLETAKNYLEQKCYLWNSGMFMFKASVYLDELKKFRPDILAAC
                     KESLSSASTDLDFIRLNSDVFAECPDESIDYAVMEKTQDCVVIPLDADWSDIGSWTSL
                     WEISEKDEHENVSHGDVINYNSRNNYIYSEGSLISTVGVNNLIIVQTKDALLVAQQDN
                     VQDIKKIVEILKKQKRSEHISHREVYRPWGRYDSVERGDRYQVKRITVKPGECLSTQM
                     HHHRAEHWVVVAGTAKVTCGERTFFVTENESTFIPIGTVHTLENPGKIPLEVIEIQSG
                     VYLGDDDIVRLSDKYGRVEDK"
     gene            4779..6200
                     /gene="manB"
     CDS             4779..6200
                     /gene="manB"
                     /note="phosphomannomutase"
                     /codon_start=1
                     /transl_table=11
                     /product="ManB"
                     /protein_id="AAY23744.1"
                     /translation="MNITNDVIKNSGIAFGTSGARGLVKDFTPNVCAAFTYAFIDVMM
                     KDFSFKEVALAIDNRPSSYAMAQACAAALLECSIKPIYYGVIPTPALANQAIADGIPA
                     IMVTGSHIPFDRNGLKFYRPDGEISKENENSIIHAEKEYPDVTVLPELQCSKRAADTY
                     IERNTSIFSNIFKGKRIGIYEHSSAGRDLYSEIFSKLGAEVVSIGRSDEFVPIDTEAV
                     SKEDEEKALHWSSEYDLDMIFSTDGDGDRPLVADENGVWLRGDILGLFCSKAMNIEAV
                     AVPVSCNTVIQTCGWFNHVTLTKIGSPYVISAFDSLNNSFDRVAGFEANGGYLLGSDV
                     NYNSGMIKALPTRDAVLPALMVLALAIKNNVTISKLLAELPPRFTYSNRVQNFATSKS
                     KSIIASAQENPQEFIERIGFVDLHVQSVDTIDGLRLTLSDGSIIHLRPSGNAPELRCY
                     AEADNIIKAEKLVLEVLHKVTLL"
     gene            6384..7715
                     /gene="wzy"
     CDS             6384..7715
                     /gene="wzy"
                     /note="O antigen polymerase"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzy"
                     /protein_id="AAY23745.1"
                     /translation="MHKQYYSLLCNKIQFKHLAIYFSVFLSLSSCFLWGGADTFVSQV
                     YIDILATISTALLVVLMFYYYINRVRYLSLTLLFAFVFSLIIGLPSIYLYYFKNANHG
                     FEIICIWGMLINSILYLQTTETVIKEEKRYLTSLFYILFSIVALCQLYKILIYLMFIL
                     NSGEGHLAIYTESEELLSQVPFFIRAISGFAVVMSLSTFYFKTPTYIKVIAFVLLASD
                     LAIGIRNKFFFSVICIFILYMYSNEYRVRNLFKQLSKPIFLIAGFLCFSMVSYFREGY
                     QIDFMIYIGIVLDSLSSTLGGMQNLFDMQSSGWDQLHPAVVFTQVLPLSGLGFLDDQQ
                     IAKDFSIIVLGDVSSGIALSSSGLLESSLLSLNLGVIIYLLYLSGVMLFIKWGLNNQR
                     IIINFVAISMISGFFYAVRGELILPLAFLLKSLPIVLISPLLVKNKIYHGQ"
     gene            7757..8992
                     /gene="wzx"
     CDS             7757..8992
                     /gene="wzx"
                     /note="O antigen transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzx"
                     /protein_id="AAY23746.1"
                     /translation="MIKEIFSDGIFSLFNKICYFGFKTLAIILITRSLGEDVGGEFIF
                     LVGFLEVLRVVTDFGVDLFVIKKYNDSTDKIKLLNVTFAQKILSGVIVLLLFCLYSFV
                     QGYQYNVYIPIVLALPVALFFNFSNSYFQSLNSNKSLTFPIAIASIATCTIFAIQYFL
                     NVKFNAWDYLCVELLFVSLVTLKLFVSVKFRFIRTSAFDVLMSILSLYKYTLSIGLTA
                     VVVIIYSRIDNFYLKTFAPGDLAAYGQIFRMVDPLVMVSSVFSTVAYARFCRINLQEK
                     NAFTKVFQFLLCIVAYGVLSSLVYFFIIKYLGHFVLISNVNNDFLIMMFLIVACVKCI
                     NGGTTAIIQSQGFYKVGLYVSYVCILTSIPTMYFLIMKYGVKGAAMTILLVECISFLL
                     LLCSFFMIKKMRPKKTFEM"
ORIGIN      
        1 attgtggctg cagggatcaa agaaatcctc ctggtaactc acgcgtccaa gaacgcggtc
       61 gaaaaccact tcgacacctc ttatgaatta gaatctctcc ttgaacagcg cgtgaagcgt
      121 caactactgg cggaagtgca gtccatctgt ccgccgggcg tgaccattat gaacgtgcgt
      181 cagggcgaac ctttaggttt gggccactcc attttatgtg cacgacctgc cattggtgac
      241 aacccatttg tcgtggtact gccagacgtt gttatcgacg acgccagtgc cgacccgcta
      301 cgctataacc ttgctgccat gattgcgcgc ttcaatgaaa cgggccgtag ccaggtgctg
      361 gcaaaacgta tgccgggcga tctctctgaa tactccgtca tccagactaa agagccgctg
      421 gaccgtgagg gtaaagtcag ccgcattgtt gaatttatcg aaaaaccgga tcagccgcag
      481 acgctggact cagacatcat ggccgtgggc cgttatgtgc tttctgccga tatttggccg
      541 gaacttgaac gcacgcagcc tggtgcatgg ggacgtattc agctgactga tgccattgct
      601 gaactggcga aaaaacagtc cgttgatgcc atgctgatga ccggcgacag ctacgactgc
      661 ggtaaaaaaa tgggctatat gcaggcgttt gtgaagtatg gactgcgcaa cctgaaggaa
      721 gggccaaagt tccgtaagag cattgagaag ttgctcgggg aatagatcca agccaatgta
      781 acaataattt agataaatag cggcagctaa catcccggcg tctatgcttt aaacaaagga
      841 atgttactgt cgtttttctt tttaaaacaa agaataacaa cgagttaacc tactaagttt
      901 aatctatttt ttgttggatt tatccttgtt tctgacagca tttggtaaga caattggcgt
      961 ttgaatttaa ggtagctttg cgatagctag cggggcgggg tacatctttg gcattttgct
     1021 agtgcactgg tagctgttaa gccaggggcg gtagcgtggt aagattgtgt ttatatgatg
     1081 cgttctcaaa ataagaaata ataatcctga ctatttttat actattgata atatctgaaa
     1141 taaacttaag agcaaacatg aaagtaattg taaataattt ttttgatggt attttgaaaa
     1201 gaggaatacc gatctatact tctgaacttg tgcaaaagtt aagagacaat aatgttcagg
     1261 ttatttatgt tgcatgtcca aaagcattcc ataagctgcc ttcatggttt ctgaatgttc
     1321 tttttataat agtagagcag cttttaatac caattatggg tatattttat agaactaagt
     1381 ataatatata tccctataat agtagttcca tcattgactt gttattaggt aaggcaattg
     1441 ttataattca tgacttcatt agtcttaaga aaaataaacg aaatcttgct gccatttatg
     1501 tgaaagtctg tatttatttt tcatcttttt tagcaaagaa agtaatattt atttctcaaa
     1561 gcactcagcg agtatctaag agaatatcgc tatttaagtg tatagaatct atcctgctcc
     1621 caaatccatt tttctcattt gagaaaattg ctaatgttac cgaaataaaa gatcttggat
     1681 atttacttct agtttcaggt ttaggggata ataaggatct aggcacagct ctggactatt
     1741 atttttcaat cccaagggaa gaaagaatac cattaaaaat attaggttgt gggaatggta
     1801 ttagcaaggt taacgactta attgatgggc gggatacaga taaagaaatt gaaattattg
     1861 gttttgtttc tttagaggaa gtcgtcaaac tatattgtaa ttctaaaatt gtttgggctc
     1921 attcgcttgc cgaggggtat ggaaggactt tagctgaagc aaaactcaca tgcaaaaatg
     1981 ttatatgcac acggatctct gctttccgcg aacaaatgga ttcgaatatt ttcttttata
     2041 cttactattc tgagtattat gaagtctatt catacttggt agataattca cccagtgtcg
     2101 aaaggaaagc tctgcatgaa catattttat ttgaaaatga attgagaaag atttatgagt
     2161 aatattgata taaataagaa acagatatta gttttgactc cacggttccc gtttcctgtc
     2221 attggtgggg atcgattacg tatctataag atctgtaaag aactgtctaa gcattatgat
     2281 cttacgttgc tgagtctgtg tgataaacgc gaagagctca actatgaata tgatcgtgaa
     2341 gtttttagta gtgttcacag agtatatctt tcaaagaaaa aatctatttt aaatgtcata
     2401 ttctctttgt tttcaaatac tcccctacag attgggtatt ataaatctaa agaatttgaa
     2461 gataaactta agcagttatt acctgaacat tctgcaactc tttcacattt gataagggtt
     2521 ggtgattatg tgaaagagaa taaagatata aattttttag agatgaccga tgccatttca
     2581 cttaattata aacgagtaaa ggaaaaagca tctttattga gtttaaaaac atttgtatat
     2641 tcttttgaac aaaaaagact cgaacgatat gagcgaacta taaataacaa gttcagcttg
     2701 actactttgg tatcacaggt tgactccgat tatttatatc cagaccgtcc gaataatgta
     2761 ttagtctgtg gaaatggtgt tgatgccgtt agcttacctt tttcagaacg aaaaatagct
     2821 aaagataaaa agataaccct tgtatttata ggtaatttat attctttgca aaatatggat
     2881 ggtgtgagat ggttcaccaa ggaagtttta ccatttctta acaagcatgg taattttgaa
     2941 tttaaggtca tcggacgtat tacagataaa gataagagtt ggttagaaag ccagcctggc
     3001 gttgttgtca caggtgaagt tgatagcata acttatgcag cagctgatgg gcatattggt
     3061 gtatgtccta ttagattagg ggcaggtatc caaaataagg tacttgaata tatggcgttg
     3121 ggattacctt gtatctcttc tactgtaggc tttgaaggct tgggagcaga ggagggtaag
     3181 gagatttatg ttgccaatac aaaagaagaa tatttacgtg tattaaatta ttttataaca
     3241 aatctggata aatataccga aacagcatta gttgcgaaaa agtttatcgg tgagaatttt
     3301 tcatgggaag ctaaattgag cccatatatc cagaaaatta aggagtctgt taaataaaat
     3361 gattatccca attattatgg ccggtggttc tggtactcgc ttatggcctc tttcgcgttc
     3421 gttatacccg aaacaatttt tatcattgat taatgaaaat agtttgctcc aggaaacgtt
     3481 gaagagactt gatggattaa attgtttgcc tcctgtcatt gttagcaata atgagcatag
     3541 atttattgtt gctgaacaat tgcgacagtc cggtgtggat gacttccaga ttattctaga
     3601 acctgtaggt agaaatactg cgcccgccgt tgcgctggct gctctaaagt ctctagaact
     3661 ccatggcgat catcatatgc tggttcttgc tgctgaccat gctattcagg atattgaagc
     3721 cttccatgca gctgttttag ctgcagaaca agagtccgtt gacaataagt tagtgacttt
     3781 tggcatcgtc ccgaccaaac ctgaaactgg gtatggctat attaaaaagg gcgaacaagt
     3841 taaaaactct gtatttaaag taaattcttt cgtcgaaaaa cctgatttag aaacggctaa
     3901 aaattatctc gaacaaaaat gctatttgtg gaatagtggt atgttcatgt tcaaggcgag
     3961 cgtatattta gatgaattga aaaaatttcg ccctgatatt ttagcagcgt gtaaagagtc
     4021 gctttccagt gctagtactg atctagattt tatcagatta aattctgatg tctttgcaga
     4081 atgtcccgat gagtcaattg attatgcggt aatggaaaaa actcaggatt gtgtagttat
     4141 tccacttgat gctgactgga gtgacatcgg ttcatggaca tcactttggg aaatatcaga
     4201 gaaagatgaa catgaaaacg tatcgcatgg cgatgtaatt aactataaca gcaggaacaa
     4261 ctacatttac tctgaaggtt cactgatcag cactgtagga gttaataacc ttattatagt
     4321 tcaaactaaa gatgcgctcc tggtagcaca gcaagacaac gtacaagaca taaagaagat
     4381 tgtcgaaatt cttaaaaagc aaaaacgtag cgaacatata tcccatcgcg aagtctatcg
     4441 tccttgggga cgttatgatt ctgtagaacg tggcgaccgt tatcaggtaa aacgtattac
     4501 cgttaagcct ggtgaatgtc tctcaacaca aatgcatcat catcgagctg agcattgggt
     4561 ggttgtcgct ggtactgcaa aggtgacttg cggcgaacgc acttttttcg tcactgaaaa
     4621 tgagtcaact ttcataccaa ttggcacagt tcataccttg gaaaatccag gaaagatacc
     4681 attagaagta attgagattc agtcgggtgt atatctaggt gatgatgata ttgtgcgcct
     4741 aagtgataaa tatggtcgtg ttgaggataa ataattatat gaatattacc aatgatgtaa
     4801 ttaaaaatag cggaattgca tttggtacaa gtggtgctcg tggattagtg aaagatttta
     4861 cacccaacgt gtgtgctgca ttcacttatg cttttatcga tgtaatgatg aaggattttt
     4921 cttttaaaga ggttgcgctc gcaatagata atcgcccaag cagctatgct atggcacaag
     4981 cttgcgcagc agcattgttg gaatgtagta ttaaacctat ttactacggt gtaattccaa
     5041 ctccagcttt ggcaaatcaa gcgattgccg atgggattcc tgcaataatg gttactggaa
     5101 gtcatattcc atttgataga aatggtttga aattctatcg tccagacggg gaaatttcaa
     5161 aagaaaatga gaacagcatt atacatgctg aaaaagagta tcctgatgta actgtattgc
     5221 cagaattaca atgttcaaag cgtgccgctg atacttatat cgagagaaac acttcaattt
     5281 tttcaaatat atttaaaggt aaacgtatcg ggatttatga acattcaagt gcgggacggg
     5341 atctttattc agaaatattc agtaagcttg gtgctgaagt tgtaagtatt ggtagaagtg
     5401 atgagtttgt gcctattgat actgaagcag tatcaaaaga agatgaagaa aaagctttac
     5461 actggtcatc tgagtatgac ctcgatatga ttttttctac cgatggtgat ggcgatcgtc
     5521 ctttggttgc tgacgaaaat ggcgtttggt tacggggtga tatattagga ctattttgct
     5581 caaaggcaat gaatattgaa gcggtagctg tacctgtaag ttgtaatacg gttattcaga
     5641 cttgcgggtg gtttaatcat gtaacgctga ctaaaattgg ttcaccatac gtcatttcag
     5701 cgtttgattc tctgaataat agttttgata gggttgcagg gtttgaggct aacggtgggt
     5761 atcttttagg tagcgatgta aattataaca gcggtatgat taaagcgctt ccaacaagag
     5821 atgctgtttt gcctgcttta atggtactgg cactggctat aaaaaataat gtgactattt
     5881 caaaactctt ggcggagttg ccaccacgat ttacctactc aaatagagtt caaaattttg
     5941 caacaagcaa aagcaaaagc attatcgcgt cagctcaaga aaatcctcaa gaatttatcg
     6001 aaagaatagg ctttgtcgat cttcatgtac aatcggtgga tacaattgac gggttaagat
     6061 tgacactaag tgatggttca ataatccatt tgcgaccgtc aggcaacgca cctgaattgc
     6121 gatgctatgc agaagcagat aacataataa aagctgaaaa attagtgtta gaagttttgc
     6181 ataaagttac tcttttgtaa aaaaatataa acttttttct actcttgagc ggtttgtcat
     6241 ttaaccgctc agtaatagat tgtttataaa ttgtttatat ttagcattgg tatttttatt
     6301 tgcgttcatc ccgaataaga gattgtaaaa ttaactgttt cttatttttc aaatgagtta
     6361 cttcactagt aaagctaatt actatgcata agcaatatta ttcattattg tgcaataaaa
     6421 tacagtttaa acatctggct atatattttt ctgtatttct ttcactatcc tcatgtttct
     6481 tgtggggagg ggcggataca tttgtatcgc aagtgtatat tgatatttta gccactatat
     6541 ctacagcgct attagttgtt ttgatgttct attattatat taatagagtt cgctatttat
     6601 cactaacctt actttttgca ttcgtttttt ctttgattat tggtttgcca tcgatttatc
     6661 tttactattt taaaaacgca aatcatgggt ttgaaataat ttgtatctgg gggatgttga
     6721 tcaattccat cctttacttg caaacaacag agactgtcat aaaagaagaa aaaagatatt
     6781 taactagttt attttatatt ttgttttcta ttgttgcact gtgtcaatta tacaaaatat
     6841 taatttatct tatgtttata ttgaattcag gagaagggca tttagcaatt tatactgaaa
     6901 gcgaagaatt gctatcccaa gttccatttt ttattcgtgc tattagtggt tttgcagttg
     6961 taatgtcatt gtccactttt tattttaaaa caccgaccta cattaaagtt attgcatttg
     7021 ttttacttgc atctgattta gctattggaa tacgtaataa gtttttcttt tcagtgattt
     7081 gtatttttat actatatatg tactctaatg agtatagagt aagaaattta tttaagcagc
     7141 tctcaaaacc aatatttctc atcgccggtt ttttatgctt ctcgatggta tcgtatttcc
     7201 gtgaagggta ccaaatcgat tttatgattt atattggcat tgttttagat tcgctatcct
     7261 ctactcttgg ggggatgcag aatttgtttg atatgcaatc atcaggatgg gatcaacttc
     7321 atcccgctgt ggtattcaca caagtattac cgctaagcgg tcttggtttt cttgatgatc
     7381 aacaaatcgc aaaagatttt tcaataattg ttttaggtga tgtatcctct ggtattgcgt
     7441 tgtcatcttc aggattgtta gagtcatcgt tgctgagtct aaacttggga gtgattattt
     7501 atttactgta tttatcaggg gtgatgctat ttattaaatg gggactaaat aatcaacgga
     7561 taataataaa ctttgttgcc atctccatga tatctggatt tttttatgct gttcgtggtg
     7621 aactgatttt gccattggct tttcttctaa aatcattgcc gattgttctt atatctccat
     7681 tacttgttaa aaataaaatt tatcatggtc agtaagtggt ttatttttcg accaggatct
     7741 caccagtagg catgacatga tcaaagaaat tttctccgat ggcatttttt cgctatttaa
     7801 taaaatatgt tacttcggtt ttaaaacact tgcaataatt ctgattactc gttccttagg
     7861 agaagatgta ggcggagagt tcattttttt agttggtttt ctcgaagtcc ttcgggtggt
     7921 tactgatttt ggtgtggatc tgtttgttat aaaaaaatat aatgattcta cagataaaat
     7981 aaaactatta aatgtaacgt ttgcacaaaa aattctttct ggagtaattg ttttactact
     8041 gttttgtttg tattcttttg ttcagggtta tcaatataat gtctatattc ctattgtgtt
     8101 agccttacct gttgctttat tttttaattt ctcaaatagc tattttcaat ctctcaattc
     8161 caataaatct ctcacgtttc cgatcgcaat tgcatctatt gcaacgtgta cgatcttcgc
     8221 tattcagtat tttttaaacg ttaaatttaa cgcatgggat tacctgtgtg ttgaactatt
     8281 attcgtatcg ctggttacac taaaactatt cgttagtgtc aagtttaggt ttattagaac
     8341 gtcagctttt gatgtgctaa tgtcaattct ttctttatat aaatatacat taagtatagg
     8401 tcttacagct gttgttgtaa ttatttatag ccgtatagat aatttttatc tcaagacatt
     8461 tgccccaggg gatcttgcag catatggcca gatatttagg atggttgatc cactggttat
     8521 ggtttcttct gtattttcta cagttgccta tgcaagattt tgccgaatta acttacaaga
     8581 aaaaaatgct tttactaagg tgtttcagtt cctgttatgt attgtggcat atggcgtgct
     8641 gagttcatta gtttatttct ttataataaa atacttgggt cattttgtat tgatttctaa
     8701 tgttaataat gatttcttga taatgatgtt cttgattgtt gcatgtgtga aatgtatcaa
     8761 tggtggtaca actgcaataa ttcagtcaca ggggttttat aaagtgggtt tgtatgtttc
     8821 gtatgtttgc attttgacat cgataccaac tatgtatttc ttaataatga agtacggtgt
     8881 taaaggtgct gctatgacga ttctacttgt agagtgtatt agtttcttat tacttctctg
     8941 cagctttttt atgataaaaa agatgcgtcc taaaaaaaca ttcgaaatgt aatcaatgag
     9001 tcctctttga atagaattag tttgttctat ttatgaacac ttagcttgag taagttctaa
     9061 catagattac taattgtttg atactatctg ctttacaagc ataaccgcgt atgtcgcggt
     9121 gaccacacct gacaggagta tgtaatgtcc aagcaacaga tcggcgtcgt cggtatggca
     9181 gtgatggggc gcaacctggc gctcaacatc gaaagccgtg gttataccgt ctccgtcttc
     9241 aaccgctccc gcgaaaaaac tgaagaagtt gttgccgaga acccgggtaa gaaactggtt
     9301 ccttattaca cggtgaaaga gtttgtcgag tctcttgaaa cccctcgtcg catcctgtta
     9361 atggtgaaag caggtgcagg cacggatgct gctattgatt ccctcaaacc atatctcgat
     9421 aaaggtgaca tcatcattga tggtggtaac accttcttcc aggacactat tcgtcgtaat
     9481 cgtgagcttt cagcagaggg ctttaacttc atcggtaccg gtgtttccgg cggtgaagag
     9541 ggggcgttga aagggccttc catcatgcct ggtgggcaga aagaagccta tgaactggtt
     9601 gcaccaattc tgaccaaaat cgccgcagta gctgaagacg gtgagccatg cgttacctat
     9661 attggtgccg atggcgcagg tcactatgtg aagatggttc acaacggtat tgagtacggc
     9721 gatatgcaac tgattgctga agcctattct ctgcttaaag gtggcctgaa cctcaccaac
     9781 gaagaactgg cgcagacctt taccgagtgg aataacggtg aactgagcag ctacctgatc
     9841 gacatcacta aagacatctt cactaaaaaa gatgaagacg gtaactacct ggttgatgtg
     9901 attctggatg aagcagcaaa caaaggtacc ggtaaatgga ctagccagag cgcgctggat
     9961 ctcggcgaac cgctgtcgct gattaccgag tctgtgtttg cacgttatat ctcttctctg
    10021 aaagatcagc gcgttgccgc gtctaaagtt ctcactggcc cgaaagcaca gccagcaggc
    10081 gataaggctg agtttatcga gaaagttcgc cgtgcgctgt atctgggtaa aatcgtttct
    10141 tacgctcagg gcttctctca gctgcgtgcg gcgtctgaag agtacaactg ggatctgaat
    10201 tacggcgaaa tcgcgaagat tttccgtgct ggctgcatca tccgtgcaca gttcctgcag
    10261 aaaatcaccg atgcttatgc cgaaaatccg cagatcgcta acctgctgct ggctccgtac
    10321 ttcaagcaaa ttgccgatga ctaccagcag gcgctgcgtg atgtcgttgc ttatgcagta
    10381 cagaacggta tcccggttcc gaccttcgcg gctgcggttg cctattatga cagctaccgc
    10441 gccgcagttc tgcctgcgaa cttaattcag gcccagcgcg acta
//

</pre>